Heme Oxygenase 1 (HMOX1) (NM_002133) Human Tagged ORF Clone Lentiviral Particle
- LentiORF®
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
|---|---|
| Tag | Myc-DDK |
| Target Symbol | Heme Oxygenase 1 |
| Synonyms | bK286B10; HMOX1D; HO-1; HSP32 |
| Vector | pLenti-C-Myc-DDK |
| Mammalian Cell Selection | None |
| Sequence Data | |
| ACCN | NM_002133 |
| ORF Size | 864 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NM_002133.1 |
| RefSeq Size | 1606 bp |
| RefSeq ORF | 867 bp |
| Locus ID | 3162 |
| UniProt ID | P09601 |
| Cytogenetics | 22q12.3 |
| Domains | Heme_oxygenase |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Porphyrin and chlorophyll metabolism |
| MW | 32.8 kDa |
| Summary | Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. provided by RefSeq, Jul 2008 |
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