Ptgs2 (NM_011198) Mouse Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
MR227684L3V
Lenti ORF particles, Ptgs2 (Myc-DDK-tagged) - Mouse prostaglandin-endoperoxide synthase 2 (Ptgs2), 200ul, >10^7 TU/mL
  $1,393.00
5 Weeks*
Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol Ptgs2
Synonyms COX; Cox-; Cox-2; COX2; gripghs; PES-2; Pgh; PGHS; PGHS-2; Pghs2; PHS; PHS-2; PHS II; Tis; TIS10
Vector pLenti-C-Myc-DDK-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR227684).
ACCN NM_011198
ORF Size 1812 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_011198.3
RefSeq Size 4150 bp
RefSeq ORF 1815 bp
Locus ID 19225
UniProt ID Q05769
Cytogenetics 1 63.84 cM
Summary This gene encodes an enzyme that is a member of the prostaglandin G/H synthase family. The encoded protein converts arachidonic acid to prostaglandin endoperoxide H2 which is a key enzymatic step in prostaglandin biosynthesis. This gene is the inducible prostaglandin G/H synthase family member that is upregulated during inflammation. Aberrant regulation of this gene is associated with cancer progression in several tissues and an increased risk of cardiovascular events. This gene is the target of many non-steroidal anti-inflammatory drugs. provided by RefSeq, Sep 2015
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Documents
Resources

file-alt Citations

IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs
Wang, Huang, Liu et al
Oncotarget (2016)
Cited by 37
AI Summary: OriGene products contributed to this study by providing shRNA vectors for RGS4 (TR30007) and PTGS2 (TG310074) mRNAs, which were used to manipulate gene expression in MDA231 breast cancer cells to investigate the role of IMP1 in tumor growth and metastasis.
Snippet: shRNA vectors for RGS4 and PTGS2 mRNAs were purchased from OriGene Technologies (TR30007 and TG310074). The vectors were used to infect MDA231 cells. MDA231 cells infected with the above vectors were seeded in a Cite SaveSaving
Showing 1-1 of 1 papers.
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