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ITIH1 (NM_001166434) Human Untagged Clone

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SKU
SC329124
ITIH1 (untagged)-Human inter-alpha (globulin) inhibitor H1 (ITIH1) transcript variant 2
  $776.00
3 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol ITIH1
Synonyms H1P; IATIH; IGHEP1; ITI-HC1; ITIH; SHAP
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>SC329124 representing NM_001166434.
Blue=Insert sequence Red=Cloning site Green=Tag(s)

GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
ATGGAGCAATTCACCATCCACCTCACCGTCAATCCCCAGAGCAAGGTCACGTTTCAGCTGACTTATGAG
GAAGTGCTGAAGAGAAACCATATGCAGTATGAAATTGTCATCAAAGTCAAGCCCAAGCAGCTGGTGCAT
CATTTTGAGATTGATGTGGACATCTTCGAGCCCCAGGGGATCAGCAAGCTGGATGCCCAGGCCTCTTTC
CTGCCGAAGGAACTGGCAGCCCAAACTATCAAGAAGTCCTTCTCAGGAAAAAAGGGTCATGTGCTGTTC
CGTCCCACCGTGAGCCAGCAGCAGTCCTGCCCCACATGCTCTACATCCTTACTGAACGGGCACTTCAAG
GTGACCTACGATGTCAGTCGAGACAAGATCTGCGACCTCCTGGTGGCCAATAACCACTTTGCCCACTTC
TTTGCCCCCCAAAACCTGACAAACATGAACAAGAACGTGGTTTTTGTGATTGACATCAGTGGCTCCATG
AGAGGCCAGAAAGTGAAGCAGACCAAGGAGGCACTCCTTAAAATTCTGGGGGACATGCAGCCAGGGGAC
TACTTTGACCTGGTTCTTTTTGGGACTCGAGTACAATCGTGGAAGGGCTCGCTGGTGCAAGCATCTGAG
GCCAACCTACAAGCAGCTCAAGACTTTGTGCGGGGCTTTTCCCTGGATGAGGCCACAAACCTGAATGGA
GGTTTGCTCCGGGGAATTGAGATCTTGAACCAAGTTCAGGAAAGCCTCCCAGAACTCAGCAACCATGCC
TCAATACTCATCATGTTGACAGATGGCGATCCCACAGAGGGGGTGACGGACCGTTCCCAAATCCTCAAG
AACGTCCGCAACGCCATCCGGGGCAGGTTCCCGCTCTACAACCTGGGTTTCGGCCACAATGTGGACTTT
AACTTTCTGGAGGTCATGTCCATGGAGAACAACGGACGGGCCCAGAGAATCTACGAGGACCATGATGCC
ACCCAGCAGCTGCAGGGTTTCTACAGCCAGGTAGCCAAACCCCTGCTGGTGGATGTGGATTTGCAGTAC
CCCCAGGATGCTGTCTTGGCCCTGACCCAGAACCACCATAAACAGTACTACGAAGGCTCAGAGATTGTG
GTGGCCGGGCGCATTGCTGACAACAAACAGAGCAGCTTCAAGGCTGATGTGCAGGCCCATGGGGAGGGA
CAAGAATTCAGTATAACCTGCCTAGTGGATGAGGAGGAGATGAAGAAACTGCTCCGAGAGCGTGGCCAC
ATGCTGGAGAACCACGTCGAGCGCCTCTGGGCCTACCTCACCATCCAGGAGCTGCTGGCCAAGCGGATG
AAGGTGGACAGGGAGGAGAGGGCCAACCTGTCATCCCAGGCCCTGCAGATGTCGCTGGACTATGGGTTT
GTGACCCCACTGACCTCCATGAGCATCAGGGGCATGGCGGACCAGGACGGCCTGAAGCCCACCATCGAC
AAGCCCTCAGAGGATTCTCCGCCTTTGGAGATGCTGGGACCCAGAAGGACGTTCGTGCTGTCAGCCTTG
CAGCCTTCTCCTACTCATTCCAGCTCCAATACCCAGCGGCTGCCAGACCGAGTGACCGGCGTGGACACA
GACCCTCACTTCATCATCCACGTGCCCCAGAAAGAGGACACCCTGTGCTTCAACATCAATGAGGAGCCT
GGTGTTATCCTGAGCCTGGTACAGGACCCCAACACAGGCTTCTCAGTGAATGGACAGCTCATTGGCAAC
AAGGCCAGGAGCCCTGGGCAGCATGACGGCACGTACTTCGGGCGGCTGGGAATCGCAAACCCTGCCACG
GACTTTCAGTTGGAAGTGACTCCTCAGAACATTACGCTGAACCCCGGCTTTGGTGGGCCTGTGTTTTCC
TGGAGGGACCAAGCTGTGCTGCGGCAGGACGGGGTGGTGGTGACCATCAACAAGAAGAGGAACCTGGTG
GTGTCTGTGGACGACGGTGGCACCTTTGAGGTTGTTTTGCACCGAGTGTGGAAGGGGAGCTCGGTCCAC
CAGGACTTCCTGGGCTTCTATGTGCTGGACAGTCATCGGATGTCAGCCCGGACGCACGGGCTGCTGGGG
CAATTTTTCCACCCCATCGGTTTTGAAGTGTCTGACATCCACCCAGGCTCTGACCCCACAAAGCCAGAT
GCCACGATGGTGGTGAGGAACCGCCGGCTCACGGTCACCAGGGGTTTGCAAAAAGACTACAGCAAGGAC
CCGTGGCATGGGGCCGAGGTGTCCTGCTGGTTCATTCACAACAATGGGGCTGGACTCATCGATGGTGCC
TACACTGATTATATCGTCCCCGACATCTTCTGA
ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
Restriction Sites SgfI-MluI |
ACCN NM_001166434
Insert Size 2310 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001166434.2
RefSeq Size 2762 bp
RefSeq ORF 2310 bp
Locus ID 3697
UniProt ID P19827
Cytogenetics 3p21.1
Protein Families Transmembrane
MW 86.2 kDa
Summary This gene encodes a member of the inter-alpha-trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and fertilization, and has been implicated in multiple inflammatory diseases. This gene is present in a gene cluster on chromosome 3. provided by RefSeq, Nov 2015
Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter N-terminus and lacks a predicted signal peptide compared to isoform a.
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Documents
Resources
"NM_001166434" in other vectors (4)
SKU Description Size Price
RC230486 ITIH1 (Myc-DDK-tagged)-Human inter-alpha (globulin) inhibitor H1 (ITIH1), transcript variant 2 10 ug
$704.00
RC230486L3 Lenti-ORF clone of ITIH1 (Myc-DDK-tagged)-Human inter-alpha (globulin) inhibitor H1 (ITIH1), transcript variant 2 10 ug
$1,004.00
RC230486L4 Lenti-ORF clone of ITIH1 (mGFP-tagged)-Human inter-alpha (globulin) inhibitor H1 (ITIH1), transcript variant 2 10 ug
$1,004.00
RG230486 ITIH1 (tGFP-tagged) - Human inter-alpha (globulin) inhibitor H1 (ITIH1), transcript variant 2 10 ug
$904.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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