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PCSK7 (NM_004716) Human Untagged Clone

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SKU
SC323814
PCSK7 (untagged)-Human proprotein convertase subtilisin/kexin type 7 (PCSK7)
  $720.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol PCSK7
Synonyms LPC; PC7; PC8; SPC7
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_004716.2 CACTGCTCCTCCGGCTCCCGGGAAGCCGCGAGTTTCCGCAGGGAGGCGGCGGCAGCTGCG
GCGGGGCCGGTCTGTAGCCTTTGCTGAGTCAACACTACTCACAGTGAAAGTGATGCCTTT
TCTCCATTTGCACAACATGAGTGTGACGTGGTTAGCCAGACCAGGAGCTCAACCTCATGT
AGAATCCAGTCCACTGCTCTGATGCCGAAGGGGAGGCAGAAAGTGCCACACTTGGATGCC
CCCCTGGGCCTGCCCACCTGCCTCTGGCTGGAATTAGCCGGGCTCTTCTTACTGGTTCCC
TGGGTCATGGGCCTGGCAGGGACAGGTGGGCCTGATGGCCAGGGCACAGGGGGGCCGAGC
TGGGCTGTGCACCTGGAAAGCCTGGAAGGTGACGGGGAGGAAGAGACTCTGGAGCAGCAG
GCGGATGCCTTGGCCCAGGCAGCAGGGCTGGTGAATGCTGGACGCATCGGAGAGCTTCAG
GGGCACTACCTCTTTGTCCAGCCTGCTGGGCACAGGCCGGCCCTGGAGGTGGAGGCCATC
CGGCAGCAGGTGGAGGCTGTGTTGGCTGGGCATGAAGCTGTGCGCTGGCACTCAGAGCAG
AGGCTGCTAAGGCGGGCCAAGCGCAGCGTCCACTTCAACGACCCCAAGTACCCGCAGCAA
TGGCACCTGAATAACCGACGGAGCCCGGGCAGGGACATCAACGTGACGGGTGTGTGGGAA
CGCAATGTGACTGGGCGAGGGGTGACGGTGGTGGTAGTGGATGACGGAGTGGAACACACC
ATCCAGGACATTGCACCCAACTATAGCCCTGAGGGTAGCTATGACCTCAACTCTAATGAC
CCTGACCCCATGCCCCACCCGGATGTGGAGAATGGCAACCACCATGGCACGCGATGTGCA
GGAGAGATCGCGGCTGTGCCCAACAACAGCTTCTGTGCCGTGGGCGTGGCCTACGGGAGC
CGCATCGCAGGTATCCGGGTACTGGATGGACCTCTCACAGACAGCATGGAGGCAGTGGCG
TTCAACAAGCACTATCAGATCAATGACATCTACAGCTGCAGCTGGGGACCAGATGACGAT
GGGAAGACAGTGGATGGCCCCCATCAGCTTGGAAAGGCTGCCTTACAACATGGGGTGATT
GCTGGTCGCCAGGGCTTTGGGAGCATCTTTGTGGTAGCCAGTGGCAACGGAGGCCAACAC
AACGACAACTGCAACTACGATGGCTACGCCAACTCCATCTACACCGTCACCATAGGAGCT
GTGGATGAGGAGGGACGCATGCCTTTCTATGCAGAAGAATGTGCCTCCATGCTGGCAGTC
ACCTTCAGTGGTGGGGACAAGATGCTTCGGAGCATTGTGACCACTGACTGGGACCTTCAG
AAGGGCACTGGCTGCACTGAGGGCCACACAGGGACCTCAGCTGCAGCGCCTCTGGCAGCT
GGCATGATAGCCTTAATGCTGCAGGTGCGGCCCTGCCTCACGTGGCGTGACGTCCAGCAC
ATCATTGTCTTCACAGCCACCCGGTATGAGGATCGCCGTGCAGAGTGGGTCACCAACGAG
GCAGGCTTCAGCCATAGCCACCAGCACGGTTTCGGCCTCCTCAACGCCTGGAGGCTCGTG
AATGCAGCCAAGATCTGGACATCTGTCCCTTACTTAGCATCCTACGTCAGTCCCGTGTTA
AAAGAAAACAAGGCGATTCCGCAGTCCCCCCGTTCCCTGGAGGTCCTGTGGAATGTCAGC
AGGATGGACCTGGAGATGTCAGGGCTGAAGACCCTGGAGCATGTGGCAGTGACAGTCTCC
ATCACTCACCCACGGCGCGGCAGCTTGGAGCTGAAGCTGTTCTGCCCCAGTGGCATGATG
TCCCTCATCGGCGCCCCCCGCAGCATGGACTCGGATCCCAACGGCTTCAATGACTGGACC
TTCTCCACTGTGCGATGCTGGGGGGAGAGAGCCCGAGGGACCTACAGGCTTGTCATCAGG
GATGTCGGGGATGAGTCATTCCAGGTCGGCATCCTCCGGCAATGGCAGCTGACCCTATAT
GGCTCTGTGTGGAGTGCAGTAGACATCAGGGACAGACAAAGGCTGTTAGAGAGTGCCATG
AGTGGAAAATACCTGCACGATGACTTCGCCCTGCCCTGCCCACCGGGGCTGAAAATTCCT
GAGGAAGATGGTTACACCATCACCCCCAACACCCTCAAGACCCTGGTGCTGGTAGGCTGT
TTCACCGTCTTCTGGACTGTTTACTACATGCTGGAAGTATATTTGAGCCAGAGGAATGTG
GCTTCCAATCAAGTTTGTAGGAGTGGACCCTGCCACTGGCCCCATCGGAGCCGGAAAGCC
AAGGAGGAAGGGACAGAGCTAGAATCAGTGCCACTTTGCAGCAGCAAGGATCCAGACGAA
GTGGAAACAGAGAGCAGGGGCCCTCCCACCACCTCTGACCTCCTTGCCCCAGACCTGCTG
GAGCAAGGGGACTGGAGCCTGTCCCAGAACAAGAGCGCCCTGGACTGCCCTCATCAGCAC
CTAGACGTACCGCACGGGAAGGAGGAGCAGATCTGCTGACCTCAGGGCCTGACAGTGTGG
GACAGGCTCTTCTTTCCCAAAATTAGGGAGCTCTTGACAGAAAGCAGTTCTGATGCTTAC
ATCTGGAATCTGAGGCATCCTCTGACTCCACTCAAAGAGGGTGAGGGCCTTCTTAAGATA
CAAATGGTGGAGGATTGCTGCCAGAGAAGTCTGGTCAGAGCCACAGGGTCTGCCTCCAGC
CAAACGGGAGCTTTTGGTGAGAAGGTGTTGGACAGGGGATTGGCGCCCCCCTTTGGTTTG
GCCTCCATCCTCATCTCTCTTGGGCCAAGCCAGCTGCCTAGGTCCCCCAAGCATGGGGGA
CCCCTTCCCACATATAAGTTGAGAAGGTGCCTGCCATAGCCAGGAGCGCATCTCAATGGA
AACATCACTGGGGTCACTTGGGAAGAGGACTTCGGGGTAGAGGCTGGGAGGAGCCCCTGG
ACATGCCTGTCCTGAAAGCGGCTGCCTCCATTATCCATTCCCAAGATGCCTGATCAGAAA
CCAACCATGAATGAACCCCTGGCTCCTTCACCACCCCCACGATTGGTATGATGCTGCCGG
CACAGCTGGGATACACACGGCTCCCCCAGGCCTGAGCTGCTTCACTAGGGAATCCTGCGG
CAGGACTGCAGAGCAGATGGCAGATGCACATGTTGGAGGAGAGAGCCTTGGGAGCCACTG
CCACTCCAGTCCTGCCACCACCCTGTCTTCCTCTGCAAGTGCTCAGGGAAATGGCCTTCC
CGCCGGAGGCCAGCTATCTGCCTGACAGGCTGTGACTCTTCTCTCAACCTTGGCCTTCTC
CCCTCTTCTGAGCTAGTTGGTTGAATTTTTTTTAATGCTTAAGATTTGTTTTTCTCTTTT
CACAGCAACATTTTCTTGAATTTTTTTCTGCACAGCTTTTCCAAAATAAAAACCTTCCAA
ACAAAAAAAAAAAAAAA
Restriction Sites ECoRI-NOT |
ACCN NM_004716
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_004716.2, NP_004707.2
RefSeq Size 3497 bp
RefSeq ORF 2358 bp
Locus ID 9159
UniProt ID Q16549
Cytogenetics 11q23.3
Domains Peptidase_S8, P_proprotein
Protein Families Druggable Genome, Protease, Transmembrane
Summary This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes and plays a role in the regulation of iron metabolism. A t(11;14)(q23;q32) chromosome translocation associated with B-cell lymphoma occurs between this gene and its inverted counterpart. provided by RefSeq, Feb 2014
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"NM_004716" in other vectors (7)
SKU Description Size Price
RC203896 PCSK7 (Myc-DDK-tagged)-Human proprotein convertase subtilisin/kexin type 7 (PCSK7) 10 ug
$719.00
RC203896L1 Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 7 (PCSK7), Myc-DDK-tagged 10 ug
$1,019.00
RC203896L2 Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 7 (PCSK7), mGFP tagged 10 ug
$1,019.00
RC203896L3 Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 7 (PCSK7), Myc-DDK-tagged 10 ug
$1,019.00
RC203896L4 Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 7 (PCSK7), mGFP tagged 10 ug
$1,019.00
RG203896 PCSK7 (tGFP-tagged) - Human proprotein convertase subtilisin/kexin type 7 (PCSK7) 10 ug
$789.00 $919.00
SC117224 PCSK7 (untagged)-Human proprotein convertase subtilisin/kexin type 7 (PCSK7) 10 ug
$720.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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