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MXI1 (NM_001008541) Human Untagged Clone

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SKU
SC323767
MXI1 (untagged)-Human MAX interactor 1 (MXI1), transcript variant 3
  $300.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol MXI1
Synonyms bHLHc11; MAD2; MXD2; MXI
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_001008541.1 CATCGCCCGAGGCGTCCGCCCTGCAAATCTGCCAGCCCCCGAGAGGGGTTTGGAACCTTA
GCACCCAAGTCTAAGTCAACTTCATAGTGTGAACATGGCTACGCCTCTTCATTCCCGTCC
ATGCCGAGCCCCCGACTGCAGCATTCAAAGCCCCCACGGAGGTTGAGCCGGGCACAGAAA
CACAGCAGCGGGAGCAGCAACACCAGCACTGCCAACAGACGAGCTCATCTGCGCCTTTGT
TTAGAACGCTTAAAAGTTCTGATTCCACTAGGACCAGACTGCACCCGGCACACAACACTT
GGTTTGCTCAACAAAGCCAAAGCACACATCAAGAAACTTGAAGAAGCTGAAAGAAAAAGC
CAGCACCAGCTCGAGAATTTGGAACGAGAACAGAGATTTTTAAAGTGGCGACTGGAACAG
CTGCAGGGTCCTCAGGAGATGGAACGAATACGAATGGACAGCATTGGATCAACTATTTCT
TCAGATCGTTCTGATTCAGAGCGAGAGGAGATTGAAGTGGATGTTGAAAGCACAGAGTTC
TCCCATGGAGAAGTGGACAATATAAGTACCACCAGCATCAGTGACATTGATGACCACAGC
AGCCTGCCGAGTATTGGGAGTGACGAGGGTTACTCCAGTGCCAGTGTCAAACTTTCATTC
ACTTCATAGAACCCAGCATGACATAACAGTGCAGGGCAAAATATTCACTGGGCCAATTCA
ATACAAACAATCTCTTAAATTGGGTTCATGATGCAGTCTCCTCTTTAAAACAAAACAAAA
CAAAACTATACTTGAACAAAAGGGTCAGAGGACCTGTATTTAAGCAAATACTTAGCAAAA
AGTGGGGCAGAGCCTCCCAAGGAGAACAAATATTCAGAATATTCATACTGGAAAAATCAC
AATTTTTAATGGCAGCAGAAAACTTGTGTGAAATTTTCTTGATTTGAGTTGATTGAGAAG
AGGACATTGGAGATGCCATCCTCTTTCTCTTTTCTAGTTTGCTCATACTACATTGAGTAG
ACACATTTAAGGATGGGGTTATGAACCCTTCCTGAGCTTTATGGTCCTAAAAGCAAAATA
AAAACTATTTGAATGAAAAGACAAGAAAATCAGGTATTAATCTTGGATAGCTAATAATGA
GCTATTAAAACTCAGCCTGGGACAGTTTATCATGAAGCCTGTGGATGATCAATCCTTTAT
TATTATTTTTTTTTTTTTGAAAAAAGCTCATTTCATGCTCTGCAAAAGGAGAGACTCCCA
TGAAGCCTTTTGAAAGGGATCATCATGCAGCTCAACTTTCTGTTGGATTCCATGCTAAGC
AAGCTAACCTTATCCTGCATTGTTAGCACTAGGCACCCAGCTGCCACCTCTCCATCCTGC
TGCCCTTAGGCCACATGGGAGCAGTCCATGCATGACAGCCTCTATCCTACAAGGCCTATG
AGTATGGATTGGGGGGGCCAAAAGGAAAAAGCTCCATGTGCCTCTTTGTCTGCGTGGGTC
AGAAGAGTTGTGCACGCAGATTAGCAGGCCAAGGTCTGAGCCACAGCAGCATTTTTATTT
CAGATTTTGATAACTGTTTATATGTGTTGAAAACCAAAATGACATCTTTTTAAAGCTTAT
CCATAAAAAAAAATAGATGTCTTTTATAGTGGAAAAACACATGGGGAAAAAAATCATCTA
TTTTGATGCAGCATTTGATAATGATAAAACACCTCACACCTCACTCTTTATAGTGCACAA
AATGAATGAGGTCTGGGCTAGGTAGAAAAAGGGTCAATGCTATTTTTTGTTTTTAGAATC
ATTACCTTTTACCAGCTTTTAACCATCTGATATCTATAGTAGACACACTATCATAGTTAA
CATAGTTAAGTTCAGCACTTGTCTCATTTTAATGTAAAGATTTGCTTCCATTTTCCTACA
GGCAGTCTCTCTCTTCCTCACAGTCCCACTGTGCAGGTGCTATTGTTACTCTTACGAATA
TTTTCAGTAATGTTATTTTCTTCTAAGTGAAATTTCTAGCCTGCACTTTGATGTCATGTG
TTCCCTTTGTCTTTCAAACTCCAAGGTTCCCCTGTGGCCCTCTCCCTTACCCTGGGAAGG
CCTCTTGGAGACCTTACCCCTGGCTGTTTGGACTTTGTATACTTTAAATAATTTAACTAC
CCTTAATTACTTAAAAAAAAAAAAAAA
Restriction Sites ECoRI-NOT |
ACCN NM_001008541
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001008541.1, NP_001008541.1
RefSeq Size 3047 bp
RefSeq ORF 549 bp
Locus ID 4601
UniProt ID P50539
Cytogenetics 10q25.2
Protein Families Druggable Genome, Transcription Factors
Summary Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. provided by RefSeq, Jul 2008
Transcript Variant: This variant (3), also referred to as WR, differs in the 5' UTR and lacks an alternate in-frame exon, compared to variant 1. The resulting protein (isoform c) is shorter, compared to isoform a. This variant is supported by mRNAs and ESTs but the existence of the protein product has not been verified experimentally.
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Documents
Resources
"NM_001008541" in other vectors (4)
SKU Description Size Price
RC202332 MXI1 (Myc-DDK-tagged)-Human MAX interactor 1 (MXI1), transcript variant 3 10 ug
$300.00
RC202332L3 Lenti ORF clone of Human MAX interactor 1 (MXI1), transcript variant 3, Myc-DDK-tagged 10 ug
$600.00
RC202332L4 Lenti ORF clone of Human MAX interactor 1 (MXI1), transcript variant 3, mGFP tagged 10 ug
$600.00
RG202332 MXI1 (tGFP-tagged) - Human MAX interactor 1 (MXI1), transcript variant 3 10 ug
$500.00

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