COPRS (NM_018405) Human Untagged Clone

SKU
SC323765
COPRS (untagged)-Human chromosome 17 open reading frame 79 (C17orf79)
  $300.00
In Stock*
Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol COPRS
Synonyms C17orf79; COPR5; HSA272196; TTP1
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_018405.2 CCACGGCGTCCAGGGCGACCAGCCGCGGGCCGCAGGGCATGGACCTTCAGGCCGCCGGGG
CCCAGGCGCAGGGGGCCGCGGAGCCGTCTCGGGGCCCGCCGCTGCCTAGCGCGCGGGGGG
CGCCCCCCAGCCCGGAGGCTGGCTTTGCTACAGCTGACCACTCCGGTCAGGAGAGAGAGA
CTGAGAAGGCTATGGATCGACTAGCCCGTGGAACACAGAGCATTCCTAATGACAGTCCTG
CCCGGGGTGAGGGCACCCATTCTGAAGAGGAAGGCTTTGCCATGGATGAGGAGGACTCTG
ATGGAGAACTGAATACCTGGGAGCTGTCAGAAGGGACAAACTGTCCACCCAAGGAACAGC
CTGGCGATCTTTTTAATGAGGACTGGGACTCGGAGTTGAAAGCAGATCAAGGGAATCCAT
ATGATGCTGACGACATCCAGGAGAGCATTTCTCAAGAGCTTAAACCTTGGGTGTGCTGTG
CCCCACAAGGAGACATGATCTATGACCCCAGCTGGCACCATCCGCCTCCACTGATACCCT
ATTATTCCAAGATGGTCTTTGAAACAGGACAGTTTGACGATGCTGAAGATTGAGTGTGGA
GCTTTCTGCCTTGTAGGTGGGCGGGCCTCCACGTCAAGATCTCTTTTCCTGTCTTGGAGG
TGAAAAGTCATATCTGAGAAAATGTTTGCAGTGACCCCTAGTCTGGGGTACACAGACCAG
TGTTCCTTATTGACAGTGTTCAATAAGGCCCCGTCATTCTCGCCAGTCTGTTGTTGTTCT
TAATGGGCTCCTCCTTGAAATGTGTGTGTGTTTGTGTCAAGAGGAGTTGTGTTCTTTGTA
AATAAAGGTTAAAAAAAAAAA
Restriction Sites ECoRI-NOT |
ACCN NM_018405
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_018405.2, NP_060875.1
RefSeq Size 861 bp
RefSeq ORF 555 bp
Locus ID 55352
UniProt ID Q9NQ92
Cytogenetics 17q11.2
Summary Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression. Plays a role in muscle cell differentiation by modulating the recruitment of PRMT5 to the promoter of genes involved in the coordination between cell cycle exit and muscle differentiation (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
"NM_018405" in other vectors (4)
SKU Description Size Price
RC203910 COPRS (Myc-DDK-tagged)-Human chromosome 17 open reading frame 79 (C17orf79) 10 ug
$300.00
RC203910L3 Lenti ORF clone of Human chromosome 17 open reading frame 79 (C17orf79), Myc-DDK-tagged 10 ug
$600.00
RC203910L4 Lenti ORF clone of Human chromosome 17 open reading frame 79 (C17orf79), mGFP tagged 10 ug
$600.00
RG203910 COPRS (tGFP-tagged) - Human chromosome 17 open reading frame 79 (C17orf79) 10 ug
$500.00

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