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SOCS6 (NM_004232) Human Untagged Clone

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SKU
SC322430
SOCS6 (untagged)-Human suppressor of cytokine signaling 6 (SOCS6)
  $499.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol SOCS6
Synonyms CIS-4; CIS4; HSPC060; SOCS-4; SOCS-6; SOCS4; SSI4; STAI4; STATI4
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>OriGene sequence for SC322430 GGAGAAGGCGAGCGCGGCAGTCGCGCCGGCGCTGGGCGAGGAAGCGGAGCCGGGCCGCCT
CCGGAAAATGGCTCCAAAGGTTAAATGAAGCAGGAAAAATACATAGATGCAGCCTTGCAG
CCTCTCCAGATGTTTGGGGATAATATTCCAGATAGAAATATTGATCCCTTGGATTAGGTA
ACTAGTCATAATGAAGAAAATTAGTCTTAAAACCTTACGGAAATCTTTTAACTTGAATAA
AAGTAAAGAAGAAACTGATTTCATGGTAGTACAACAACCATCGCTAGCCAGTGACTTTGG
AAAAGATGATTCCTTATTTGGTAGCTGCTATGGTAAAGATATGGCCAGCTGCGATATCAA
CGGTGAAGATGAAAAAGGCGGAAAAAACAGATCAAAAAGCGAGAGCCTGATGGGTACGCT
AAAAAGGCGGCTTTCTGCAAAACAGAAGTCAAAAGGCAAGGCGGGCACACCCTCTGGGAG
CTCTGCCGACGAGGACACCTTCTCCTCCTCCTCAGCACCCATAGTCTTTAAAGACGTGAG
AGCTCAGAGGCCGATAAGGTCCACGTCGCTCCGCAGCCATCACTACAGTCCCGCGCCGTG
GCCTCTGCGGCCCACAAACTCCGAGGAGACCTGCATCAAGATGGAGGTGAGAGTCAAGGC
CTTGGTTCACTCTTCCAGCCCGAGTCCAGCCCTGAATGGCGTCCGGAAGGATTTCCACGA
CCTCCAGTCTGAGACCACGTGCCAGGAGCAAGCCAATTCACTGAAGAGCTCGGCTTCTCA
TAATGGAGACCTGCATCTTCACCTGGATGAACATGTGCCTGTCGTTATTGGACTTATGCC
TCAGGACTACATTCAGTATACTGTGCCTTTAGATGAGGGGATGTATCCTTTGGAAGGATC
ACGGAGCTATTGTCTGGACAGCTCTTCTCCCATGGAAGTCTCTGCGGTTCCTCCTCAAGT
GGGAGGGCGCGCTTTCCCCGAGGATGAGAGTCAGGTAGACCAGGACCTAGTTGTCGCCCC
AGAGATCTTCGTGGATCAGTCCGTGAATGGCTTGTTGATTGGCACCACGGGAGTCATGTT
GCAGAGCCCGAGAGCGGGTCACGATGATGTCCCTCCACTCTCACCATTGCTACCTCCAAT
GCAGAATAATCAAATCCAAAGGAACTTCAGTGGACTCACTGGCACAGAAGCCCACGTGGC
TGAAAGTATGCGCTGTCATTTGAATTTTGATCCGAACTCTGCTCCTGGGGTTGCAAGAGT
TTATGACTCAGTGCAAAGTAGTGGTCCCATGGTTGTGACAAGCCTTACAGAGGAGCTGAA
AAAACTTGCAAAGCAAGGATGGTACTGGGGACCAATCACACGTTGGGAGGCAGAAGGGAA
GCTAGCAAACGTGCCAGATGGTTCTTTTCTTGTTCGGGACAGTTCTGACGACCGTTACCT
TTTAAGCTTGAGCTTTCGCTCCCATGGTAAAACACTTCACACTAGAATTGAGCACTCAAA
TGGTAGGTTTAGCTTTTATGAACAGCCAGATGTGGAAGGACATACGTCCATAGTTGATCT
AATTGAGCATTCAATCAGGGACTCTGAAAATGGAGCTTTTTGTTATTCAAGGTCTCGGCT
GCCTGGATCTGCAACTTACCCCGTCAGACTGACCAACCCAGTGTCCCGGTTCATGCAGGT
GCGCTCGTTGCAGTACCTGTGTCGTTTTGTTATACGTCAGTATACCAGAATAGACTTAAT
TCAGAAACTGCCTTTGCCAAACAAAATGAAGGATTATTTACAGGAGAAGCACTACTGAAA
GATTGAGAACCCTGCATCTTGCACTTTGGGAATAAGAACAAGAGATTGAAATACAGTTTA
CAAACTTTCATTGCCATCAAAATCTTTTGCTGCCATAACTATTTCAGTTTTATGTGTAAA
AGAGTCATCAGTTTGTTTAGGGGTGGGGAAGTGTCAGCAAGGTGTCTTGGGTTTATTTTG
GTTCTTTAAAAAAGGGAAGTCTTGAGGTTTTAGAGGTGTGAATTATGTTTCATCAATGTG
CAGAATAATCACAATGTGAATTATCAAATTCTCCTCAATGCCCCCCCCGCCCAGTCCTTT
GCTGCTATCCACTGTGATTTTTATGCATTAAAAGCACATTTCATGTGTATTCAACCCTAA
GTAAAGTTGAATGAAACTTAACAGAATGGAAATTGCTATGTCTTTTTAAATGGTCCATTT
TCAAAAGACAGTGTTGAATAAACATACCTGTGTGATAAAACACAGAATTTACATATACAC
TGAAGATGAGTTTTTAATCTCTTACTTTAAAAAGATTTATTTAGAATCGTGAATTGACAT
AATCTTGGGTAATGGAACGGAGATCTGCAACATATCTTTTAACAACACTTTTTTCTAAAT
TATTTCTAAGGTTGTGCTAATTCTTTTGGTTGTGAAAAGTTGAATTTTTCTGTTGCCTTC
GTTTTCATCTTCTAGTTTGTCTATTTTAATAAATGGCCTTACATTAAAAAATTGTAAAGA
AATGTATACCACCAATTTAGAAATTGTTGCCTTTTCTGTAATTAAACTCGGGTACAAATT
GGCATAACATGAAAACCTATGGAACTAGAATTATTATTAAAGAAATATTAGATGAAAAAA
AAAAAAAAAA
Restriction Sites Please inquire |
ACCN NM_004232
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_004232.3, NP_004223.2
RefSeq Size 5846 bp
RefSeq ORF 1608 bp
Locus ID 9306
UniProt ID O14544
Cytogenetics 18q22.2
Domains SH2, SOCS
Protein Families Druggable Genome
Summary The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. provided by RefSeq, Jul 2008
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Documents
Resources
"NM_004232" in other vectors (7)
SKU Description Size Price
RC202224 SOCS6 (Myc-DDK-tagged)-Human suppressor of cytokine signaling 6 (SOCS6) 10 ug
$498.00
RC202224L1 Lenti ORF clone of Human suppressor of cytokine signaling 6 (SOCS6), Myc-DDK-tagged 10 ug
$798.00
RC202224L2 Lenti ORF clone of Human suppressor of cytokine signaling 6 (SOCS6), mGFP tagged 10 ug
$798.00
RC202224L3 Lenti ORF clone of Human suppressor of cytokine signaling 6 (SOCS6), Myc-DDK-tagged 10 ug
$798.00
RC202224L4 Lenti ORF clone of Human suppressor of cytokine signaling 6 (SOCS6), mGFP tagged 10 ug
$798.00
RG202224 SOCS6 (tGFP-tagged) - Human suppressor of cytokine signaling 6 (SOCS6) 10 ug
$489.00 $698.00
SC124420 SOCS6 (untagged)-Human suppressor of cytokine signaling 6 (SOCS6) 10 ug
$499.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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