TUSC3 (NM_178234) Human Untagged Clone
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | TUSC3 |
| Synonyms | D8S1992; M33; MagT2; MRT7; MRT22; N33; OST3A; SLC58A2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | Please inquire | |
| ACCN | NM_178234 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_178234.1, NP_839952.1 |
| RefSeq Size | 1548 bp |
| RefSeq ORF | 1044 bp |
| Locus ID | 7991 |
| UniProt ID | Q13454 |
| Cytogenetics | 8p22 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Metabolic pathways, N-Glycan biosynthesis |
| Summary | This gene encodes a protein that has been associated with several biological functions including cellular magnesium uptake, protein glycosylation and embryonic development. This protein localizes to the endoplasmic reticulum and acts as a component of the oligosaccharyl transferase complex which is responsible for N-linked protein glycosylation. This gene is a candidate tumor suppressor gene. Homozygous mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation-7 and in the proliferation and invasiveness of several cancers including metastatic pancreatic cancer, ovarian cancer and glioblastoma multiform. provided by RefSeq, Oct 2017 Transcript Variant: This variant (2) lacks an exon in the 3' region compared to variant 1. The resulting isoform (b) contains a one aa shorter and distinct C-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_178234" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC203082 | TUSC3 (Myc-DDK-tagged)-Human tumor suppressor candidate 3 (TUSC3), transcript variant 2 | 10 ug |
$457.00
|
|
| RC203082L1 | Lenti ORF clone of Human tumor suppressor candidate 3 (TUSC3), transcript variant 2, Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC203082L2 | Lenti ORF clone of Human tumor suppressor candidate 3 (TUSC3), transcript variant 2, mGFP tagged | 10 ug |
$757.00
|
|
| RC203082L3 | Lenti ORF clone of Human tumor suppressor candidate 3 (TUSC3), transcript variant 2, Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC203082L4 | Lenti ORF clone of Human tumor suppressor candidate 3 (TUSC3), transcript variant 2, mGFP tagged | 10 ug |
$757.00
|
|
| RG203082 | TUSC3 (tGFP-tagged) - Human tumor suppressor candidate 3 (TUSC3), transcript variant 2 | 10 ug |
$489.00
$657.00
|
|
Citations
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