TUSC3 (NM_178234) Human Untagged Clone

SKU
SC319771
TUSC3 (untagged)-Human tumor suppressor candidate 3 (TUSC3), transcript variant 2
  $457.00
In Stock*
Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol TUSC3
Synonyms D8S1992; M33; MagT2; MRT7; MRT22; N33; OST3A; SLC58A2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_178234.1 GGGGGCCTTTCCAGGTCTTCTCCCGGTGAACCGGATGCTCTGTCAGTCTCCTCCTCTGCG
TCCTCGGCCGCGGCCCGGGTCCCTCGCAAAGCCGCTGCCATCCCGGAGGGCCCAGCCAGC
GGGCTCCCGGAGGCTGGCCGGGCAGGCGTGGTGCGCGGTAGGAGCTGGGCGCGCACGGCT
ACCGCGCGTGGAGGAGACACTGCCCTGCCGCGATGGGGGCCCGGGGCGCTCCTTCACGCC
GTAGGCAAGCGGGGCGGCGGCTGCGGTACCTGCCCACCGGGAGCTTTCCCTTCCTTCTCC
TGCTGCTGCTGCTCTGCATCCAGCTCGGGGGAGGACAGAAGAAAAAGGAGAATCTTTTAG
CTGAAAAAGTAGAGCAGCTGATGGAATGGAGTTCCAGACGCTCAATCTTCCGAATGAATG
GTGATAAATTCCGAAAATTTATAAAGGCACCACCTCGAAACTATTCCATGATTGTTATGT
TCACTGCTCTTCAGCCTCAGCGGCAGTGTTCTGTGTGCAGGCAAGCTAATGAAGAATATC
AAATACTGGCGAACTCCTGGCGCTATTCATCTGCTTTTTGTAACAAGCTCTTCTTCAGTA
TGGTGGACTATGATGAGGGGACAGACGTTTTTCAGCAGCTCAACATGAACTCTGCTCCTA
CATTCATGCATTTTCCTCCAAAAGGCAGACCTAAGAGAGCTGATACTTTTGACCTCCAAA
GAATTGGATTTGCAGCTGAGCAACTAGCAAAGTGGATTGCTGACAGAACGGATGTTCATA
TTCGGGTTTTCAGACCACCCAACTACTCTGGTACCATTGCTTTGGCCCTGTTAGTGTCGC
TTGTTGGAGGTTTGCTTTATTTGAGAAGGAACAACTTGGAGTTCATCTATAACAAGACTG
GTTGGGCCATGGTGTCTCTGTGTATAGTCTTTGCTATGACTTCTGGCCAGATGTGGAACC
ATATCCGTGGACCTCCATATGCTCATAAGAACCCACACAATGGACAAGTGAGCTACATTC
ATGGGAGCAGCCAGGCTCAGTTTGTGGCAGAATCACACATTATTCTGGTACTGAATGCCG
CTATCACCATGGGGATGGTTCTTCTAAATGAAGCAGCAACTTCGAAAGGCGATGTTGGAA
AAAGACGGATAATTTGCCTAGTGGGATTGGGCCTGGTGGTCTTCTTCTTCAGTTTTCTAC
TTTCAATATTTCGTTCCAAGTACCACGGCTATCCTTATAGCTTTTTAATTAAATGAAGCC
AAGTGGGATTTGCATAAAGTGAATGTTTACCATGAAGATAAACTGTTCCTGACTTTATAC
TATTTTGAATTCATTCATTTCATTGTGATCAGCTAGCTTATTCTTGTGTACTTTTTTTAA
ACTGTGGGTTTTCCTAGTAAATTTAATTTACAGAAATCAATGGTAGCATTTAGTAATCTA
CAAAGGAAATATCAAAGTGTTTTTCAAGCCTGTTATATTCAGTGTGTGCCACAGGATTGA
AATAAATGACAATGTAATTATGAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire |
ACCN NM_178234
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_178234.1, NP_839952.1
RefSeq Size 1548 bp
RefSeq ORF 1044 bp
Locus ID 7991
UniProt ID Q13454
Cytogenetics 8p22
Protein Families Druggable Genome, Transmembrane
Protein Pathways Metabolic pathways, N-Glycan biosynthesis
Summary This gene encodes a protein that has been associated with several biological functions including cellular magnesium uptake, protein glycosylation and embryonic development. This protein localizes to the endoplasmic reticulum and acts as a component of the oligosaccharyl transferase complex which is responsible for N-linked protein glycosylation. This gene is a candidate tumor suppressor gene. Homozygous mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation-7 and in the proliferation and invasiveness of several cancers including metastatic pancreatic cancer, ovarian cancer and glioblastoma multiform. provided by RefSeq, Oct 2017
Transcript Variant: This variant (2) lacks an exon in the 3' region compared to variant 1. The resulting isoform (b) contains a one aa shorter and distinct C-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
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Documents
Resources
"NM_178234" in other vectors (6)
SKU Description Size Price
RC203082 TUSC3 (Myc-DDK-tagged)-Human tumor suppressor candidate 3 (TUSC3), transcript variant 2 10 ug
$457.00
RC203082L1 Lenti ORF clone of Human tumor suppressor candidate 3 (TUSC3), transcript variant 2, Myc-DDK-tagged 10 ug
$757.00
RC203082L2 Lenti ORF clone of Human tumor suppressor candidate 3 (TUSC3), transcript variant 2, mGFP tagged 10 ug
$757.00
RC203082L3 Lenti ORF clone of Human tumor suppressor candidate 3 (TUSC3), transcript variant 2, Myc-DDK-tagged 10 ug
$757.00
RC203082L4 Lenti ORF clone of Human tumor suppressor candidate 3 (TUSC3), transcript variant 2, mGFP tagged 10 ug
$757.00
RG203082 TUSC3 (tGFP-tagged) - Human tumor suppressor candidate 3 (TUSC3), transcript variant 2 10 ug
$489.00 $657.00

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