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CASTOR1 (NM_001037666) Human Untagged Clone

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SKU
SC319521
GATSL3 (untagged)-Human GATS protein-like 3 (GATSL3)
  $300.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol CASTOR1
Synonyms GATSL3
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_001037666.1 GTCCGCGCGAGCCGCGATGGAGCTGCACATCCTAGAACACCGGGTGCGGGTGCTGAGCGT
CGCCCGTCCCGGTCTCTGGCTCTACACCCACCCGCTCATCAAGCTGCTCTTCCTGCCCCG
CCGCAGCCGGTGCAAGTTCTTCAGCCTGACGGAGACCCCTGAGGATTACACGCTTATGGT
GGACGAGGAGGGCTTTAAAGAGCTGCCCCCATCTGAGTTCCTGCAAGTAGCTGAGGCCAC
ATGGCTGGTGCTGAACGTGTCGTCTCACAGCGGTGCGGCAGTGCAGGCTGCTGGGGTCAC
CAAGATCGCCCGTTCGGTCATCGCGCCACTGGCCGAGCACCACGTGTCTGTGCTGATGCT
GTCCACTTACCAGACGGACTTCATCCTGGTGCGGGAGCAGGACCTGTCCGTGGTGATCCA
CACGCTGGCCCAGGAGTTCGACATTTACCGCGAGGTGGGCGGAGAGCCTGTGCCTGTGAC
GAGGGATGATTCCAGCAATGGCTTTCCCCGCACTCAGCATGGGCCCAGCCCCACGGTGCA
TCCCATCCAGAGCCCACAGAACCGCTTCTGTGTCCTCACACTGGACCCTGAGACGCTTCC
AGCCATCGCCACCACCCTCATAGATGTCCTCTTCTACTCGCACAGCACCCCCAAGGAGGC
AGCCTCTAGCAGTCCTGAACCCAGCTCCATCACGTTCTTTGCCTTCTCCCTCATCGAGGG
TTATATCTCCATTGTCATGGATGCTGAAACACAGAAAAAGTTCCCCAGTGACCTCCTGCT
GACCAGCTCCTCGGGGGAGCTGTGGAGGATGGTGCGCATCGGTGGACAGCCCCTGGGCTT
TGATGAATGTGGCATCGTGGCACAGATTGCAGGTCCCCTGGCTGCCGCTGACATCTCTGC
CTACTACATCAGCACCTTCAACTTCGACCACGCCCTGGTGCCCGAGGACGGTATCGGCAG
CGTCATCGAGGTCCTCCAGCGGCGGCAGGAAGGCCTGGCTTCCTGAGGCCCATGGGCAAC
AGAGCAGCCTCCCTGCTCTCCCCTCGACCCAGGCTTCCAAAGACTTCTCTAAGCTATTTC
CTTAAGCTCTGGAACGAGCCCCCTGTTCTGCTGGGGACCCTCGTTCCGCTCTCTGTATGT
AAGCTGCGTGCAGGCACCGGCTTTTACGCGGACACCTGTGTACACTCACAGGTGGAGTGG
GCAGGTGCTAGCCTGACTGCGTGTCTGCCCATGCAGGGGAACACGGTGCTCGGGGCTTAA
GCCCCCAACCCATCACTCCCTGCGCAGCCTCGGCGTTTGCACAGTCCCTGCCTGAGGCCT
GAGCCATTCCCCAAAGGCTTCCTGGGCCAGCTGCCCCCCTGACCTCCGTTCTGCCTCTGG
TGGGGTTGCCTTCCCTGGCCAGGTGAGTCCTGACAGTGCCTCTCCCTCCTGGGGCCTCCA
AGGAAAGTATTTTGACATCTCTCTCTCTCTTCTGTTTTTATTGACTTGTTAATAAAGGAC
TTTGTAGTGAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire |
ACCN NM_001037666
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001037666.1, NP_001032755.1
RefSeq Size 1532 bp
RefSeq ORF 990 bp
Locus ID 652968
UniProt ID Q8WTX7
Cytogenetics 22q12.2
Summary Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.UniProtKB/Swiss-Prot Function
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Documents
Resources
"NM_001037666" in other vectors (4)
SKU Description Size Price
RC205868 GATSL3 (Myc-DDK-tagged)-Human GATS protein-like 3 (GATSL3) 10 ug
$300.00
RC205868L3 Lenti ORF clone of Human GATS protein-like 3 (GATSL3), Myc-DDK-tagged 10 ug
$600.00
RC205868L4 Lenti ORF clone of Human GATS protein-like 3 (GATSL3), mGFP tagged 10 ug
$600.00
RG205868 GATSL3 (tGFP-tagged) - Human GATS protein-like 3 (GATSL3) 10 ug
$489.00 $500.00

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