PICK1 (NM_001039583) Human Untagged Clone
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | PICK1 |
| Synonyms | PICK; PRKCABP |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_001039583 |
| Insert Size | 1248 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001039583.1 |
| RefSeq Size | 2126 bp |
| RefSeq ORF | 1248 bp |
| Locus ID | 9463 |
| UniProt ID | Q9NRD5 |
| Cytogenetics | 22q13.1 |
| Protein Families | Druggable Genome |
| MW | 46.6 kDa |
| Summary | The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene. provided by RefSeq, Jul 2008 Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein. |
Reviews
Documents
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Resources
"NM_001039583" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC222916 | PICK1 (Myc-DDK-tagged)-Human protein interacting with PRKCA 1 (PICK1), transcript variant 2 | 10 ug |
$457.00
|
|
| RC222916L3 | Lenti ORF clone of Human protein interacting with PRKCA 1 (PICK1), transcript variant 2, Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC222916L4 | Lenti ORF clone of Human protein interacting with PRKCA 1 (PICK1), transcript variant 2, mGFP tagged | 10 ug |
$757.00
|
|
| RG222916 | PICK1 (tGFP-tagged) - Human protein interacting with PRKCA 1 (PICK1), transcript variant 2 | 10 ug |
$489.00
$657.00
|
|
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