ASB7 (NM_198243) Human Untagged Clone

SKU
SC310536
ASB7 (untagged)-Human ankyrin repeat and SOCS box containing 7 (ASB7), transcript variant 2
  $330.00
3 Weeks*
Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol ASB7
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>SC310536 representing NM_198243.
Blue=Insert sequence Red=Cloning site Green=Tag(s)

GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
ATGTTACACCATCATTGTCGAAGGAACCCTGAGCTCCAGGAAGAGTTGCAGATTCAGGCCGCGGTGGCT
GCTGGGGATGTCCACACAGTGCGAAAGATGCTAGAACAAGGCTATTCCCCGAATGGCCGAGATGCGAAT
GGCTGGACTCTGCTTCATTTCTCTGCAGCAAGAGGAAAGGAAAGATGTGTTCGGGTTTTTCTAGAACAC
GGAGCTGATCCTACAGTTAAAGACTTAATCGGAGGCTTCACGGCTCTTCACTATGCAGCCATGCATGGC
CGGGCCCGCATTGCACGCTTGATGTTAGAATCTGAATACAGGAGCGACATCATTAATGCAAAAAGCAAT
GACGGCTGGACTCCCCTCCATGTGGCTGCCCACTACGGCAGGGACTCATTTGTCCGGCTCCTCCTGGAG
TTCAAGGCTGAGGTTGACCCACTCAGTGATAAAGGTACCACACCGCTTCAGCTCGCCATTATCCGAGAG
AGGTCAAGCTGTGTGAAAATCCTCCTGGACCACAATGCCAACATCGACATTCAGAATGGTTTCCTGTTG
CGATACGCCGTGATCAAAAGCAATCACTCTTATTGCCGAATGTTCCTTCAGAGAGGGGCAGACACAAAC
TTGGGTCGCTTAGAAGACGGACAGACTCCTTTACACTTATCTGCCCTTAGGGATGATGTGCTGTGTGCA
CGGATGTTATATAATTACGGAGCAGACACGAACACACGGAACTATGAAGGACAGACCCCATTGGCTGTT
TCAATAAGTATTTCTGGAAGTAGTCGACCATGTTTGGATTTCTTACAAGAAGTCACAAGACAGCCCAGA
AACTTGCAGGACCTGTGCCGAATTAAAATTCGACAATGTATAGGCCTTCAAAACCTAAAGCTACTTGAT
GAACTACCAATTGCCAAGGTCATGAAAGACTACTTAAAACACAAATTTGATGATATCTGA

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
TACAAGGATGACGACGATAAG
GTTTAAACGGCCGGC
Restriction Sites SgfI-MluI |
ACCN NM_198243
Insert Size 957 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_198243.2
RefSeq Size 4974 bp
RefSeq ORF 957 bp
Locus ID 140460
UniProt ID Q9H672
Cytogenetics 15q26.3
Protein Families Druggable Genome
MW 36 kDa
Summary The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. provided by RefSeq, Jul 2008
Transcript Variant: This variant (2) differs in the 3' CDS and UTR, compared to variant 1. The resulting protein (isoform 2) is longer and has a distinct C-terminus, compared to isoform 1.
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Documents
Resources
"NM_198243" in other vectors (6)
SKU Description Size Price
RC223249 ASB7 (Myc-DDK-tagged)-Human ankyrin repeat and SOCS box containing 7 (ASB7), transcript variant 2 10 ug
$300.00
RC223249L1 Lenti ORF clone of Human ankyrin repeat and SOCS box containing 7 (ASB7), transcript variant 2, Myc-DDK-tagged 10 ug
$600.00
RC223249L2 Lenti ORF clone of Human ankyrin repeat and SOCS box containing 7 (ASB7), transcript variant 2, mGFP tagged 10 ug
$600.00
RC223249L3 Lenti ORF clone of Human ankyrin repeat and SOCS box containing 7 (ASB7), transcript variant 2, Myc-DDK-tagged 10 ug
$600.00
RC223249L4 Lenti ORF clone of Human ankyrin repeat and SOCS box containing 7 (ASB7), transcript variant 2, mGFP tagged 10 ug
$600.00
RG223249 ASB7 (tGFP-tagged) - Human ankyrin repeat and SOCS box containing 7 (ASB7), transcript variant 2 10 ug
$500.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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