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SLC6A11 (NM_014229) Human Untagged Clone

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SKU
SC310207
SLC6A11 (untagged)-Human solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (SLC6A11)
  $589.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol SLC6A11
Synonyms GAT-3; GAT3; GAT4
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_014229 edited
CATGACGGCGGAGAAGGCGCTGCCCCTGGGCAATGGGAAGGCTGCTGAGGAGGCGCGGGA
GTCCGAGGCGCCGGGTGGCGGCTGCAGCAGCGGGGGCGCGGCGCCCGCGCGCCACCCGCG
CGTCAAGCGCGACAAGGCGGTCCACGAGCGCGGCCACTGGAACAACAAGGTGGAGTTCGT
GCTGAGCGTGGCCGGGGAGATCATTGGGCTGGGCAACGTGTGGCGCTTCCCCTACCTGTG
CTACAAGAACGGAGGAGGGGCATTCCTGATTCCCTACGTGGTGTTTTTTATTTGCTGTGG
AATTCCTGTTTTTTTCCTGGAGACAGCTCTGGGGCAGTTCACAAGTGAAGGTGGCATTAC
GTGTTGGAGGAAAGTTTGCCCTTTATTTGAAGGCATTGGCTATGCAACACAGGTGATTGA
GGCCCATCTGAATGTGTACTACATCATCATCCTGGCATGGGCCATTTTTTACCTGAGCAA
CTGCTTCACTACTGAGCTACCCTGGGCTACCTGTGGGCATGAGTGGAACACAGAGAATTG
TGTGGAGTTCCAGAAACTGAATGTGAGCAACTACAGCCATGTGTCTCTGCAGAATGCCAC
CTCCCCTGTCATGGAGTTTTGGGAGCACCGGGTCCTGGCCATCTCTGACGGGATCGAGCA
CATCGGGAACCTTCGCTGGGAGCTGGCCTTGTGTCTCTTGGCAGCCTGGACCATCTGTTA
CTTCTGTATCTGGAAGGGGACCAAGTCTACAGGAAAGGTTGTATACGTGACTGCGACATT
CCCCTACATCATGCTGCTGATCCTCCTGATACGAGGGGTCACGTTGCCCGGGGCCTCAGA
GGGCATCAAGTTCTACTTGTACCCTGACCTCTCCCGGCTCTCCGACCCCCAGGTCTGGGT
AGATGCTGGAACGCAGATCTTTTTCTCCTATGCCATTTGCCTGGGCTGTCTGACCGCTCT
GGGAAGTTATAACAATTATAACAACAACTGCTACAGGGACTGCATCATGCTCTGTTGCCT
GAACAGCGGCACCAGCTTCGTGGCTGGGTTTGCCATCTTCTCAGTCCTGGGTTTTATGGC
GTACGAGCAGGGGGTACCCATTGCTGAGGTGGCAGAGTCAGGCCCCGGCCTGGCCTTTAT
TGCGTACCCCAAGGCGGTCACCATGATGCCTCTCTCCCCGCTGTGGGCCACCTTGTTCTT
CATGATGCTCATCTTCCTGGGCCTGGACAGCCAGTTTGTGTGTGTGGAAAGCCTGGTGAC
CGCCGTGGTGGACATGTACCCCAAGGTTTTCCGGAGGGGTTACCGGCGGGAGCTGCTCAT
CCTAGCCTTGTCTGTTATCTCCTATTTTCTGGGCCTCGTGATGTTAACAGAGGGTGGCAT
GTACATCTTCCAGCTCTTTGACTCCTATGCCGCCAGTGGGATGTGCCTTCTCTTCGTGGC
CATCTTTGAGTGCATCTGCATCGGCTGGGTGTATGGAAGCAACCGGTTCTATGATAACAT
TGAAGACATGATTGGCTACCGGCCACCGTCGCTCATTAAGTGGTGCTGGATGATCATGAC
CCCTGGGATCTGCGCGGGGATCTTCATCTTCTTCTTGATCAAGTACAAGCCACTCAAGTA
CAACAACATCTACACCTACCCAGCCTGGGGCTATGGCATTGGCTGGCTCATGGCCCTGTC
CTCCATGCTCTGCATCCCGCTCTGGATCTGCATCACAGTGTGGAAGACGGAGGGGACACT
GCCCGAGAAACTCCAGAAGTTGACGACCCCCAGCACAGATCTGAAAATGCGGGGCAAGCT
TGGGGTGAGCCCACGGATGGTGACAGTTAATGACTGTGATGCCAAACTCAAGAGTGACGG
GACCATCGCAGCCATCACAGAGAAGGAGACGCACTTCTGAGCGGCCACCAGCCATCTGGG
GCTCTTCTTCCTTTCTTCCCCCCGTGTATGTAAATGAATTCCTGAACCCCATACTTCACC
TAATGGTAGGGGCTTGCTTGTTTTGCACAGGATTAATTAACAAGTTAATTTTAAGGTGGC
CACTGTACACTGCTCTAAAGTCATATCCCCTCCCCGCCATCGCCGACACACACACACGTC
GTAATGTGGCTAACGCTTGACTCACTTAACACTACTCATGGGGCAGGGCGGAGGGTGGAT
TGTTGCTTTTTGTTTTTTGTAATTTCCTACTAGTATTTGGGTAACTTTGGGGGTGGGGAG
GGCAATGTGGGGGCAGGGGAACATGTCATTGTGATGACTTTTTTGATATTCATTAGAAAC
AATACATCCTTTTTGAGATATTTACAGTATTATTAAAAAATGAAAAAGGTTGTACTGTTT
TGCATAATGAACATTTTTATTGGGCATTCAAAGGGTGCAAGATTGTCTGCTTACTCATTT
TTAAAAATTAAAGAAATGAACAATCAGTGTGGCTATTCCTAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_014229 unedited
ACCGCACCGTTTGAGCAAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGA
GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATT
CGGCACGAGGATGACGGCGGAGAAGGCGCTGCCCCTGGGCAATGGGAAGGCTGCTGAGGA
GGCGCGGGAGTCCGAGGCGCCGGGTGGCGGCTGCAGCAGCGGGGGCGCGGCGCCCGCGCG
CCACCCGCGCGTCAAGCGCGACAAGGCGGTCCACGAGCGCGGCCACTGGAACAACAAGGT
GGAGTTCGTGCTGAGCGTGGCCGGGGAGATCATTGGGCTGGGCAACGTGTGGCGCTTCCC
CTACCTGTGCTACAAGAACGGAGGAGGGGCATTCCTGATTCCCTACGTGGTGTTTTTTAT
TTGCTGTGGAATTCCTGTTTTTTTCCTGGAGACAGCTCTGGGGCAGTTCACAAGTGAAGG
TGGCATTACGTGTTGGAGGAAAGTTTGCCCTTTATTTGAAGGCATTGGCTATGCAACACA
GGTGATTGAGGCCCATCTGAATGTGTACTACATCATCATCCTGGCATGGGCCATTTTTTA
CCTGAGCAACTGCTTCACTACTGAGCTACCCTGGGCTACCTGTGGGCATGAGTGGAACAC
AGAGAATTGTGTGGAGTTCCAGAAACTGAATGTGAGCAACTACAGCCATGTGTCTCTGCA
GAATGCCACCTCCCCTGTCATGGAGTTTTGGGAGCACCGGGTCCTGGCCATCTCTGACGG
GATCGAGCACATCGGGAACCTTCGCTGGGAGCTGGCCTTGTGTCTCTTGGCAGCCTGACC
ATCTGTTACTTCTGTATCTGGAGGGGACCAAGTCTACAGGAAAGGTTGTAATACGTGACT
GCGACATTTCGTA
3' Read Nucleotide Sequence
>OriGene 3' genomic read for NM_014229 unedited
AGGGGGTGAACCTCGGGCCGGAAAGCACCGGGGAGGGGTCCAGGGATGCCCCCGGGATCT
GTTCGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGCTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTAGGAATAGCCACACTGATTGTTCATTTCTTTAATTTTTAA
AAATGAGTAAGCAGACAATCTTGCACCCTTTGAATGCCCAATAAAAATGTTCATTATGCA
AAACAGTACAACCTTTTTCATTTTTTAATAATACTGTAAATATCTCAAAAAGGATGTATT
GTTTCTAATGAATATCAAAAAAGTCATCACAATGACATGTTCCCCTGCCCCCACATTGCC
CTCCCCACCCCCAAAGTTACCCAAATACTAGTAGGAAATTACAAAAAACAAAAAGCAACA
ATCCACCCTCCGCCCTGCCCCATGAGTAGTGTTAAGTGAGTCAAGCGTTAGCCACATTAC
GACGTGTGTGTGTGTCGGCGATGGCGGGGAGGGGATATGACTTTAGAGCAGTGTACAGTG
GCCACCTTAAAATTAACTTGTTAATTAATCCTGTGCAAAACAAGCAAGCCCCTACCATTA
GGTGAAGTATGGGGTTCAGGAATTCATTTACATACACGGGGGGAAGAAAGGAAGAAGAGC
CCCAGATGGCTGGTGGCCGCTCAGAAGTGCGTCTCCTTCTCTGTGATGGCTGCGATGGTC
CCGTCACTCTTGAGTTTGGCATCACAGTCATTAACTGTCACCATCCGTGGGCTCACCCCA
AGCTTGCCCCCGCATTTTCAGATCTGTGCTGGGGGTCGTCAACTTCTGAGTTTCTCGGCA
GTGTCCCCTCCGTCTTCCACACTGTGATGCAGATCCAGAGCGGGATGCAGAGCATGAGAC
AGGCCATGAACCAGCCATGCCATAGCCCAGCTGGTTAGTGTAGATGTTGTTGTACTGATG
GCTTGTACCTTGATCAGAGAGATGAGATCAG
Restriction Sites Please inquire |
ACCN NM_014229
Insert Size 2500 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_014229.1, NP_055044.1
RefSeq Size 1991 bp
RefSeq ORF 1899 bp
Locus ID 6538
UniProt ID P48066
Cytogenetics 3p25.3
Domains SNF
Protein Families Druggable Genome, Transmembrane
Summary The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Dec 2015
Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
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Documents
Resources
"NM_014229" in other vectors (6)
SKU Description Size Price
RC216392 SLC6A11 (Myc-DDK-tagged)-Human solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (SLC6A11) 10 ug
$588.00
RC216392L1 Lenti ORF clone of Human solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (SLC6A11), Myc-DDK-tagged 10 ug
$888.00
RC216392L2 Lenti ORF clone of Human solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (SLC6A11), mGFP tagged 10 ug
$888.00
RC216392L3 Lenti ORF clone of Human solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (SLC6A11), Myc-DDK-tagged 10 ug
$888.00
RC216392L4 Lenti ORF clone of Human solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (SLC6A11), mGFP tagged 10 ug
$888.00
RG216392 SLC6A11 (tGFP-tagged) - Human solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (SLC6A11) 10 ug
$489.00 $788.00

file-alt Citations

Application of MS Transport Assays to the Four Human γ-Aminobutyric Acid Transporters
Schmitt, Höfner, Wanner
ChemMedChem (2015)
Cited by 15
AI Summary: OriGene's pCMV6-XL5 plasmid containing the hGAT-2 coding sequence (catalog number SC304440-SLC6A13) was used as the source for generating COS-7 cells stably expressing human GAT-2 in this study.
Snippet: GAT-2. For the generation of COS-7 cells stably expressing hGAT-2, the coding sequence for hGAT-2 (GenBank accession number NM_016615) of the plasmid pCMV6-XL5 (Origene, Rockville, MD, USA, number SC304440-SLC6A13) was cloned into the multiple cloning site of pCDNA3.1(+) (Invitrogen, UK) by using the restriction enzymes SacI (HF) and Xba1 (NEB, Ipswich, USA)
Showing 1-1 of 1 papers.
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