PLXNC1 (NM_005761) Human Untagged Clone

SKU SC309906

PLXNC1 (untagged)-Human plexin C1 (PLXNC1), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: PLXNC1
• Synonyms: CD232; PLXN-C1; VESPR
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005761 edited; AGGCCCACCATGGAGGTCTCCCGGAGGAAGGCGCCGCCGCGCCCCCCGCGCCCCGCAGCG; CCACTGCCCCTGCTCGCCTATCTGCTGGCACTGGCGGCTCCCGGCCGGGGCGCGGACGAG; CCCGTGTGGCGGTCGGAGCAAGCCATCGGAGCCATCGCGGCGAGCCAGGAGGACGGCGTG; TTTGTGGCGAGCGGCAGCTGCCTGGACCAGCTGGACTACAGCCTGGAGCACAGCCTCTCG; CGCCTGTACCGGGACCAAGCGGGCAACTGCACAGAGCCGGTCTCGCTGGCGCCCCCCGCG; CGGCCCCGGCCCGGGAGCAGCTTCAGCAAGCTGCTGCTGCCCTACCGCGAGGGGGCGGCC; GGCCTCGGGGGGCTGCTGCTCACCGGCTGGACCTTCGACCGGGGCGCCTGCGAGGTGCGG; CCCCTGGGCAACCTGAGCCGCAACTCCCTGCGCAACGGCACCGAGGTGGTGTCGTGCCAC; CCGCAGGGCTCGACGGCCGGCGTGGTGTACCGCGCGGGCCGGAACAACCGCTGGTACCTG; GCGGTGGCCGCCACCTACGTGCTGCCTGAGCCGGAGACGGCGAGCCGCTGCAACCCCGCG; GCATCCGACCACGACACGGCCATCGCGCTCAAGGACACGGAGGGGCGCAGCCTGGCCACG; CAGGAGCTGGGGCGCCTCAAGCTGTGCGAGGGCGCGGGCAGCCTGCACTTCGTGGACGCC; TTTCTCTGGAACGGCAGCATCTACTTCCCCTACTACCCCTACAACTATACGAGCGGCGCT; GCCACCGGCTGGCCCAGCATGGCGCGCATCGCGCAGAGCACCGAGGTGCTGTTCCAGGGC; CAGGCATCCCTCGACTGCGGCCACGGCCACCCCGACGGCCGCCGCCTGCTCCTCTCCTCC; AGCCTAGTGGAGGCCCTGGACGTCTGGGCGGGAGTGTTCAGCGCGGCCGCTGGAGAGGGC; CAGGAGCGGCGCTCCCCCACCACCACGGCGCTCTGCCTCTTCAGAATGAGTGAGATCCAG; GCGCGCGCCAAGAGGGTCAGCTGGGACTTCAAGACGGCCGAGAGCCACTGCAAAGAAGGG; GATCAACCTGAAAGAGTCCAACCAATCGCATCATCTACCTTGATCCATTCCGACCTGACA; TCCGTTTATGGCACCGTGGTAATGAACAGGACTGTTTTATTCTTGGGGACTGGAGATGGC; CAGTTACTTAAGGTTATTCTTGGTGAGAATTTGACTTCAAATTGTCCAGAGGTTATCTAT; GAAATTAAAGAAGAGACACCTGTTTTCTACAAACTCGTTCCTGATCCTGTGAAGAATATC; TACATTTATCTAACAGCTGGGAAAGAGGTGAGGAGAATTCGTGTTGCAAACTGCAATAAA; CATAAATCCTGTTCGGAGTGTTTAACAGCCACAGACCCTCACTGCGGTTGGTGCCATTCG; CTACAAAGGTGCACTTTTCAAGGAGATTGTGTACATTCAGAGAACTTAGAAAACTGGCTG; GATATTTCGTCTGGAGCAAAAAAGTGCCCTAAAATTCAGATAATTCGAAGCAGTAAAGAA; AAGACTACAGTGACTATGGTGGGAAGCTTCTCTCCAAGACACTCAAAGTGCATGGTGAAG; AATGTGGACTCTAGCAGGGAGCTCTGCCAGAATAAAAGTCAGCCCAACCGGACCTGCACC; TGTAGCATCCCAACCAGAGCAACCTACAAAGATGTTTCAGTTGTCAACGTGATGTTCTCC; TTCGGTTCTTGGAATTTATCAGACAGATTCAACTTTACCAACTGCTCATCATTAAAAGAA; TGCCCAGCATGCGTAGAAACTGGCTGCGCGTGGTGTAAAAGTGCAAGAAGGTGTATCCAC; CCCTTCACAGCTTGCGACCCTTCTGATTATGAGAGAAACCAGGAACAGTGTCCAGTGGCT; GTCGAGAAGACATCAGGAGGAGGAAGACCCAAGGAGAACAAGGGGAACAGAACCAACCAG; GCTTTACAGGTCTTCTACATTAAGTCCATTGAGCCACAGAAAGTATCGACATTAGGGAAA; AGCAACGTGATAGTAACGGGAGCAAACTTTACCCGGGCATCGAACATCACAATGATCCTG; AAAGGAACCAGTACCTGTGATAAGGATGTGATACAGGTTAGCCATGTGCTAAATGACACC; CACATGAAATTCTCTCTTCCATCAAGCCGGAAAGAAATGAAGGATGTGTGTATCCAGTTT; GATGGTGGGAACTGCTCTTCTGTGGGATCCTTATCCTACATTGCTCTGCCACATTGTTCC; CTTATATTTCCTGCTACCACCTGGATCAGTGGTGGTCAAAATATAACCATGATGGGCAGA; AATTTTGATGTAATTGACAACTTAATCATTTCACATGAATTAAAAGGAAACATAAATGTC; TCTGAATATTGTGTGGCGACTTACTGCGGGTTTTTAGCCCCCAGTTTAAAGAGTTCAAAA; GTGCGCACGAATGTCACTGTGAAGCTGAGAGTACAAGACACCTACTTGGATTGTGGAACC; CTGCAGTATCGGGAGGACCCCAGATTCACGGGGTATCGGGTGGAATCCGAGGTGGACACA; GAACTGGAAGTGAAAATTCAAAAAGAAAATGACAACTTCAATATTTCCAAAAAAGACATT; GAAATTACTCTCTTCCATGGGGAAAATGGGCAATTAAATTGCAGTTTTGAAAATATTACT; AGAAATCAAGATCTTACCACCATCCTTTGCAAAATTAAAGGCATCAAGACTGCAAGCACC; ATTGCCAACTCTTCTAAGAAAGTTCGGGTCAAGCTGGGAAACCTGGAGCTCTACGTCGAG; CAGGAGTCAGTTCCTTCCACATGGTATTTTCTGATTGTGCTCCCTGTCTTGCTAGTGATT; GTCATTTTTGCGGCCGTGGGGGTGACCAGGCACAAATCGAAGGAGCTGAGTCGCAAACAG; AGTCAACAACTAGAATTGCTGGAAAGCGAGCTCCGGAAAGAGATACGTGACGGCTTTGCT; GAGCTGCAGATGGATAAATTGGATGTGGTTGATAGTTTTGGAACTGTTCCCTTCCTTGAC; TACAAACATTTTGCTCTGAGAACTTTCTTCCCTGAGTCAGGTGGCTTCACCCACATCTTC; ACTGAAGATATGCATAACAGAGACGCCAACGACAAGAATGAAAGTCTCACAGCTTTGGAT; GCCCTAATCTGTAATAAAAGCTTTCTTGTTACTGTCATCCACACCCTTGAAAAGCAGAAG; AACTTTTCTGTGAAGGACAGGTGTCTGTTTGCCTCCTTCCTAACCATTGCACTGCAAACC; AAGCTGGTCTACCTGACCAGCATCCTAGAGGTGCTGACCAGGGACTTGATGGAACAGTGT; AGTAACATGCAGCCGAAACTCATGCTGAGACGCACGGAGTCCGTCGTCGAAAAACTCCTC; ACAAACTGGATGTCCGTCTGCCTTTCTGGATTTCTCCGGGAGACTGTCGGAGAGCCCTTC; TATTTGCTGGTGACGACTCTGAACCAGAAAATTAACAAGGGTCCCGTGGATGTAATCACT; TGCAAAGCCCTGTACACACTTAATGAAGACTGGCTGTTGTGGCAGGTTCCGGAATTCAGT; ACTGTGGCATTAAACGTCGTCTTTGAAAAAATCCCGGAAAACGAGAGTGCAGATGTCTGT; CGGAATATTTCAGTCAATGTTCTCGACTGTGACACCATTGGCCAAGCCAAAGAAAAGATT; TTCCAAGCATTCTTAAGCAAAAATGGCTCTCCTTATGGACTTCAGCTTAATGAAATTGGT; CTTGAGCTTCAAATGGGCACACGACAGAAAGAACTTCTGGACATCGACAGTTCCTCCGTG; ATTCTTGAAGATGGAATCACCAAGCTAAACACCATTGGCCACTATGAGATATCAAATGGA; TCCACTATAAAAGTCTTTAAGAAGATAGCAAATTTTACTTCAGATGTGGAGTACTCGGAT; GACCACTGCCATTTGATTTTACCAGATTCGGAAGCATTCCAAGATGTGCAAGGAAAGAGA; CATCGAGGGAAGCACAAGTTCAAAGTAAAAGAAATGTATCTGACAAAGCTGCTGTCGACC; AAGGTGGCAATTCATTCTGTGCTTGAAAAACTTTTTAGAAGCATTTGGAGTTTACCCAAC; AGCAGAGCTCCATTTGCTATAAAATACTTTTTTGACTTTTTGGACGCCCAGGCTGAAAAC; AAAAAAATCACAGATCCTGACGTCGTACATATTTGGAAAACAAACAGCCTTCCTCTTCGC; TTCTGGGTAAACATCCTGAAGAACCCTCAGTTTGTCTTTGACATTAAGAAGACACCACAT; ATAGACGGCTGTTTGTCAGTGATTGCCCAGGCATTCATGGATGCATTTTCTCTCACAGAG; CAGCAACTAGGGAAGGAAGCACCAACTAATAAGCTTCTCTATGCCAAGGATATCCCAACC; TACAAAGAAGAAGTAAAATCTTATTACAAAGCAATCAGGGATTTGCCTCCATTGTCATCC; TCAGAAATGGAAGAATTTTTAACTCAGGAATCTAAGAAACATGAAAATGAATTTAATGAA; GAAGTGGCCTTGACAGAAATTTACAAATACATCGTAAAATATTTTGATGAGATTCTAAAT; AAACTAGAAAGAGAACGAGGGCTGGAAGAAGCTCAGAAACAACTCTTGCATGTAAAAGTC; TTATTTGATGAAAAGAAGAAATGCAAGTGGATGTAAGGCCTCATGGGCCCAGCTTTCTTG; TAC;
• Restriction Sites: Please inquire
• ACCN: NM_005761
• Insert Size: 5000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_005761.1.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005761.1, NP_005752.1
• RefSeq Size: 5121 bp
• RefSeq ORF: 4707 bp
• Locus ID: 10154
• UniProt ID: O60486
• Cytogenetics: 12q22
• Domains: IPT, PSI, Sema
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Axon guidance
• Summary: This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]; Transcript Variant: This variant (1) encodes the functional protein.