OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

NR2E3 (NM_014249) Human Untagged Clone

Be the first to review this product
SKU
SC308926
NR2E3 (untagged)-Human nuclear receptor subfamily 2, group E, member 3 (NR2E3), transcript variant 2
  $457.00
In Stock*
Bulk Requests & Clone Modifications

Frequently Bought Together (4)

TA806203 NR2E3 mouse monoclonal antibody, clone OTI3D4 (formerly 3D4) 100 ul
$447.00
CC100003 DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
5 x 200 ul
$170.00
PRIMER Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
100 pmol
$59.00
TF81001 TurboFectin Transfection Reagent (1 mL in 1 vial)
1 ml in 1 vial
$530.00

Other products for "NR2E3 or NM_014249"

Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol NR2E3
Synonyms ESCS; PNR; rd7; RNR; RP37
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_014249 edited
GCCCTGTAACCCATGGAGACCAGACCAACAGCTCTGATGAGCTCCACAGTGGCTGCAGCT
GCGCCTGCAGCTGGGGCTGCCTCCAGGAAGGAGTCTCCAGGCAGATGGGGCCTGGGGGAG
GATCCCACAGGCGTGAGCCCCTCGCTCCAGTGCCGCGTGTGCGGAGACAGCAGCAGCGGG
AAGCACTATGGCATCTATGCCTGCAACGGCTGCAGCGGCTTCTTCAAGAGGAGCGTACGG
CGGAGGCTCATCTACAGGTGCCAGGTGGGGGCAGGGATGTGCCCCGTGGACAAGGCCCAC
CGCAACCAGTGCCAGGCCTGCCGGCTGAAGAAGTGCCTGCAGGCGGGGATGAACCAGGAC
GCCGTGCAGAACGAGCGCCAGCCGCGAAGCACAGCCCAGGTCCACCTGGACAGCATGGAG
TCCAACACTGAGTCCCGGCCGGAGTCCCTGGTGGCTCCCCCGGCCCCGGCAGGGCGCAGC
CCACGGGGCCCCACACCCATGTCTGCAGCCAGAGCCCTGGGCCACCACTTCATGGCCAGC
CTTATAACAGCTGAAACCTGTGCTAAGCTGGAGCCAGAGGATGCTGATGAGAATATTGAT
GTCACCAGCAATGACCCTGAGTTCCCCTCCTCTCCATACTCCTCTTCCTCCCCCTGCGGC
CTGGACAGCATCCATGAGACCTCGGCTCGCCTACTCTTCATGGCCGTCAAGTGGGCCAAG
AACCTGCCTGTGTTCTCCAGCCTGCCCTTCCGGGATCAGGTGATCCTGCTGGAAGAGGCG
TGGAGTGAACTCTTTCTCCTCGGGGCCATCCAGTGGTCTCTGCCTCTGGACAGCTGTCCT
CTGCTGGCACCGCCCGAGGCCTCTGCTGCCGGTGGTGCCCAGGGCCGGCTCACGCTGGCC
AGCATGGAGACGCGTGTCCTGCAGGAAACTATCTCTCGGTTCCGGGCATTGGCGGTGGAC
CCCACGGAGTTTGCCTGCATGAAGGCCTTGGTCCTCTTCAAGCCAGAGACGCGGGGCCTG
AAGGATCCTGAGCACGTAGAGGCCTTGCAGGACCAGTCCCAAGTGATGCTGAGCCAGCAC
AGCAAGGCCCACCACCCCAGCCAGCCCGTGAGGTTTGGGAAATTGCTCCTGCTCCTCCCG
TCTTTGAGGTTTATCACTGCGGAACGCATCGAGCTCCTCTTTTTCCGCAAGACCATAGGG
AATACTCCAATGGAGAAGCTCCTTTGTGATATGTTCAAAAACTAGTGGGGGTGGAGGTGA
AATGTTTCCAAGCACTCTGGAAAACAATCTACTGAAACGAAACATTTGCCTACTCTTTGC
CCCAGCAATTCCTCGTAGGTGTGTGTACCCAGCAGAAATGCCCACCGAAAGATATTGTAA
GAATATTCATAGCAGCTTTATTCATAATAGCCCCAAACTGTATATTGATGGTAGGATGAA
TTAACAAGTTGTGGTATATTCATATAATGAAAAATAATTTAAAAAGAATGAATTACGGAT
ACATGTGGCAACACAGGTAAACTTCACAGACATAAAAGTTGAATGAAAGAAGCCAGGCCG
AAGTTCCATTTATGCAGAGTTCAGGAACAGGCAAGACTAATTGACAATAATAGAAGTTGG
AATAGTGGTTACTTCTGGGTGGTGGGGGATTGATACAGAGGGGGCTCATGGGAGCCCTCT
GGTGTACCAGAAATGTTGATTTTGATCTGGGCAGTGGTTTCACAAATGTATTCATACGTA
ATAATTCATTGAGCTGTGCACTTTATTTTGTTAGACCTCAATAAAAAAGTAAAAAAAAAA
AAAAAAAAAAA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_014249 unedited
TGAGACCATATTGTATACCATTACTATAGGCGGCCGCGAATCACACTGGTACCGAGCTCG
GATCCACTAGTAACGGCCGCCAGTGTGCTGGAATTCGCCCTTGCCCTGTAACCCATGGAG
ACCAGACCAACAGCTCTGATGAGCTCCACAGTGGCTGCAGCTGCGCCTGCAGCTGGGGCT
GCCTCCAGGAAGGAGTCTCCAGGCAGATGGGGCCTGGGGGAGGATCCCACAGGCGTGAGC
CCCTCGCTCCAGTGCCGCGTGTGCGGAGACAGCAGCAGCGGGAAGCACTATGGCATCTAT
GCCTGCAACGGCTGCAGCGGCTTCTTCAAGAGGAGCGTACGGCGGAGGCTCATCTACAGG
TGCCAGGTGGGGGCAGGGATGTGCCCCGTGGACAAGGCCCACCGCAACCAGTGCCAGGCC
TGCCGGCTGAAGAAGTGCCTGCAGGCGGGGATGAACCAGGACGCCGTGCAGAACGAGCGC
CAGCCGCGAAGCACAGCCCAGGTCCACCTGGACAGCATGGAGTCCAACACTGAGTCCCGG
CCGGAGTCCCTGGTGGCTCCCCCGGCCCCGGCANGGCGCAGCCCACGGGGCCCCACACCC
ATGTCTGCAGCCAGAGCCTTGGGCCAACACTTCATGGCCAGCCTTATAACAGCTGAAACC
CTGTGCTAAACTGGAGCCAGAAGATCCTGATGAGAATATTGATGTCACCAGCCATGACCC
TGGAGTTCCCTCCTCTCCCTACTCCTCTTCCCTCCCCTGCGGCCTGGACAGCATTCCTGA
AAACCTGGGCTGGCCAACTTTTATGGGCCTTCAATGGGGCCAAGGAACCTGGCTTGGTTT
CCCCACCTTGCCCTTTCGGGGATCAGGAATCCTGCTGGAAAAACCCTGGAGGGAAACCTT
TCC
3' Read Nucleotide Sequence
>OriGene 3' read for NM_014249 unedited
CAGNAAAGCACTGGGGNAGGGTCACAGGGATGCCACCCGGGCTCTGTTCAGGAAACAGCT
ATGACCGCGGCCGCCCTTTTTTTTTTTTTTTACTTTTTTATTGAGGTCTAACAAAATAAA
GTGCACAGCTCAATGAATTATTACGTATGAATACATTTGTGAAACCACTGCCCAGATCAA
AATCAACATTTCTGGTACACCAGAGGGCTCCCATGAGCCCCCTCTGTATCAATCCCCCAC
CACCCAGAAGTAACCACTATTCCAACTTCTATTATTGTCAATTAGTCTTGCCTGTTCCTG
AACTCTGCATAAATGGAACTTCGGCCTGGCTTCTTTCATTCAACTTTTATGTCTGTGAAG
TTTACCTGTGTTGCCACATGTATCCGTAATTCATTCTTTTTAAATTATTTTTCATTATAT
GAATATACCACAACTTGTTAATTCATCCTACCATCAATATACAGTTTGGGGCTATTATGA
ATAAAGCTGCTATGAATATTCTTACAATATCTTTCGGTGGGCATTTCTGCTGGGTACACA
CACCTACGAGGAATTGCTGGGGCAAAGAGTAGGCAAATGTTTCGTTTCAGTAGATTGTTT
TCCAGAGTGCTTGGAAACATTTTCACCTCCCCCCCCACTAGTTTTTGAACATATCACAAA
AGAACTTCTCCATTGGAAGTATTCCCTATGGTCTTGCGGAAAAAGAGGAGCTCGATGCGT
CCCCCAGGGATAAACCTCAAAGACGGGAGGAGCAGGACCAATTTCCCAAACCTACGGGCT
GGCTGGGTGGTGGGGCCTTGCTGGGCTGGCTCAACATCAATTTGGGACTGGTCCTGGAGG
GCCTCTAGTGCCCAAGATCCCTTAAGGCCCGGGTG
Restriction Sites Please inquire |
ACCN NM_014249
Insert Size 1800 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_014249.2, NP_055064.1
RefSeq Size 1999 bp
RefSeq ORF 1233 bp
Locus ID 10002
UniProt ID Q9Y5X4
Cytogenetics 15q23
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Summary This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Jul 2008
Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (b) contains a longer C-terminus compared to isoform a.
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
"NM_014249" in other vectors (6)
SKU Description Size Price
RC215425 NR2E3 (Myc-DDK-tagged)-Human nuclear receptor subfamily 2, group E, member 3 (NR2E3), transcript variant 2 10 ug
$457.00
RC215425L1 Lenti ORF clone of Human nuclear receptor subfamily 2, group E, member 3 (NR2E3), transcript variant 2, Myc-DDK-tagged 10 ug
$757.00
RC215425L2 Lenti ORF clone of Human nuclear receptor subfamily 2, group E, member 3 (NR2E3), transcript variant 2, mGFP tagged 10 ug
$757.00
RC215425L3 Lenti ORF clone of Human nuclear receptor subfamily 2, group E, member 3 (NR2E3), transcript variant 2, Myc-DDK-tagged 10 ug
$757.00
RC215425L4 Lenti ORF clone of Human nuclear receptor subfamily 2, group E, member 3 (NR2E3), transcript variant 2, mGFP tagged 10 ug
$757.00
RG215425 NR2E3 (tGFP-tagged) - Human nuclear receptor subfamily 2, group E, member 3 (NR2E3), transcript variant 2 10 ug
$489.00 $657.00

file-alt Citations

Antisense Oligonucleotide-Based Downregulation of the G56R Pathogenic Variant Causing NR2E3-Associated Autosomal Dominant Retinitis Pigmentosa
Naessens, Ruysschaert, Lefever et al
Genes (Basel) (2019) 10 (5) DOI: 10.3390/genes10050363
AI Summary: OriGene contributed to this study by providing the wild type NR2E3 cDNA expression construct (product: TC308926), which was used as the basis for generating the mutant expression construct essential for evaluating antisense oligonucleotide-mediated gene knockdown.
Snippet: 2.2. Generation of Mutant c.166G>A Expression Construct A wild type (WT) NR2E3 (NM_014249) complementary DNA (cDNA) expression construct (OriGene, Rockville, MD, USA, TC308926) was used as a basis for mutagenesis View as HTML
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products