NR2E3 (NM_014249) Human Untagged Clone

SKU SC308926

NR2E3 (untagged)-Human nuclear receptor subfamily 2, group E, member 3 (NR2E3), transcript variant 2

Product Data

• Type: Human Untagged Clone
• Target Symbol: NR2E3
• Synonyms: ESCS; PNR; rd7; RNR; RP37
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014249 edited; GCCCTGTAACCCATGGAGACCAGACCAACAGCTCTGATGAGCTCCACAGTGGCTGCAGCT; GCGCCTGCAGCTGGGGCTGCCTCCAGGAAGGAGTCTCCAGGCAGATGGGGCCTGGGGGAG; GATCCCACAGGCGTGAGCCCCTCGCTCCAGTGCCGCGTGTGCGGAGACAGCAGCAGCGGG; AAGCACTATGGCATCTATGCCTGCAACGGCTGCAGCGGCTTCTTCAAGAGGAGCGTACGG; CGGAGGCTCATCTACAGGTGCCAGGTGGGGGCAGGGATGTGCCCCGTGGACAAGGCCCAC; CGCAACCAGTGCCAGGCCTGCCGGCTGAAGAAGTGCCTGCAGGCGGGGATGAACCAGGAC; GCCGTGCAGAACGAGCGCCAGCCGCGAAGCACAGCCCAGGTCCACCTGGACAGCATGGAG; TCCAACACTGAGTCCCGGCCGGAGTCCCTGGTGGCTCCCCCGGCCCCGGCAGGGCGCAGC; CCACGGGGCCCCACACCCATGTCTGCAGCCAGAGCCCTGGGCCACCACTTCATGGCCAGC; CTTATAACAGCTGAAACCTGTGCTAAGCTGGAGCCAGAGGATGCTGATGAGAATATTGAT; GTCACCAGCAATGACCCTGAGTTCCCCTCCTCTCCATACTCCTCTTCCTCCCCCTGCGGC; CTGGACAGCATCCATGAGACCTCGGCTCGCCTACTCTTCATGGCCGTCAAGTGGGCCAAG; AACCTGCCTGTGTTCTCCAGCCTGCCCTTCCGGGATCAGGTGATCCTGCTGGAAGAGGCG; TGGAGTGAACTCTTTCTCCTCGGGGCCATCCAGTGGTCTCTGCCTCTGGACAGCTGTCCT; CTGCTGGCACCGCCCGAGGCCTCTGCTGCCGGTGGTGCCCAGGGCCGGCTCACGCTGGCC; AGCATGGAGACGCGTGTCCTGCAGGAAACTATCTCTCGGTTCCGGGCATTGGCGGTGGAC; CCCACGGAGTTTGCCTGCATGAAGGCCTTGGTCCTCTTCAAGCCAGAGACGCGGGGCCTG; AAGGATCCTGAGCACGTAGAGGCCTTGCAGGACCAGTCCCAAGTGATGCTGAGCCAGCAC; AGCAAGGCCCACCACCCCAGCCAGCCCGTGAGGTTTGGGAAATTGCTCCTGCTCCTCCCG; TCTTTGAGGTTTATCACTGCGGAACGCATCGAGCTCCTCTTTTTCCGCAAGACCATAGGG; AATACTCCAATGGAGAAGCTCCTTTGTGATATGTTCAAAAACTAGTGGGGGTGGAGGTGA; AATGTTTCCAAGCACTCTGGAAAACAATCTACTGAAACGAAACATTTGCCTACTCTTTGC; CCCAGCAATTCCTCGTAGGTGTGTGTACCCAGCAGAAATGCCCACCGAAAGATATTGTAA; GAATATTCATAGCAGCTTTATTCATAATAGCCCCAAACTGTATATTGATGGTAGGATGAA; TTAACAAGTTGTGGTATATTCATATAATGAAAAATAATTTAAAAAGAATGAATTACGGAT; ACATGTGGCAACACAGGTAAACTTCACAGACATAAAAGTTGAATGAAAGAAGCCAGGCCG; AAGTTCCATTTATGCAGAGTTCAGGAACAGGCAAGACTAATTGACAATAATAGAAGTTGG; AATAGTGGTTACTTCTGGGTGGTGGGGGATTGATACAGAGGGGGCTCATGGGAGCCCTCT; GGTGTACCAGAAATGTTGATTTTGATCTGGGCAGTGGTTTCACAAATGTATTCATACGTA; ATAATTCATTGAGCTGTGCACTTTATTTTGTTAGACCTCAATAAAAAAGTAAAAAAAAAA; AAAAAAAAAAA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014249 unedited; TGAGACCATATTGTATACCATTACTATAGGCGGCCGCGAATCACACTGGTACCGAGCTCG; GATCCACTAGTAACGGCCGCCAGTGTGCTGGAATTCGCCCTTGCCCTGTAACCCATGGAG; ACCAGACCAACAGCTCTGATGAGCTCCACAGTGGCTGCAGCTGCGCCTGCAGCTGGGGCT; GCCTCCAGGAAGGAGTCTCCAGGCAGATGGGGCCTGGGGGAGGATCCCACAGGCGTGAGC; CCCTCGCTCCAGTGCCGCGTGTGCGGAGACAGCAGCAGCGGGAAGCACTATGGCATCTAT; GCCTGCAACGGCTGCAGCGGCTTCTTCAAGAGGAGCGTACGGCGGAGGCTCATCTACAGG; TGCCAGGTGGGGGCAGGGATGTGCCCCGTGGACAAGGCCCACCGCAACCAGTGCCAGGCC; TGCCGGCTGAAGAAGTGCCTGCAGGCGGGGATGAACCAGGACGCCGTGCAGAACGAGCGC; CAGCCGCGAAGCACAGCCCAGGTCCACCTGGACAGCATGGAGTCCAACACTGAGTCCCGG; CCGGAGTCCCTGGTGGCTCCCCCGGCCCCGGCANGGCGCAGCCCACGGGGCCCCACACCC; ATGTCTGCAGCCAGAGCCTTGGGCCAACACTTCATGGCCAGCCTTATAACAGCTGAAACC; CTGTGCTAAACTGGAGCCAGAAGATCCTGATGAGAATATTGATGTCACCAGCCATGACCC; TGGAGTTCCCTCCTCTCCCTACTCCTCTTCCCTCCCCTGCGGCCTGGACAGCATTCCTGA; AAACCTGGGCTGGCCAACTTTTATGGGCCTTCAATGGGGCCAAGGAACCTGGCTTGGTTT; CCCCACCTTGCCCTTTCGGGGATCAGGAATCCTGCTGGAAAAACCCTGGAGGGAAACCTT; TCC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014249 unedited; CAGNAAAGCACTGGGGNAGGGTCACAGGGATGCCACCCGGGCTCTGTTCAGGAAACAGCT; ATGACCGCGGCCGCCCTTTTTTTTTTTTTTTACTTTTTTATTGAGGTCTAACAAAATAAA; GTGCACAGCTCAATGAATTATTACGTATGAATACATTTGTGAAACCACTGCCCAGATCAA; AATCAACATTTCTGGTACACCAGAGGGCTCCCATGAGCCCCCTCTGTATCAATCCCCCAC; CACCCAGAAGTAACCACTATTCCAACTTCTATTATTGTCAATTAGTCTTGCCTGTTCCTG; AACTCTGCATAAATGGAACTTCGGCCTGGCTTCTTTCATTCAACTTTTATGTCTGTGAAG; TTTACCTGTGTTGCCACATGTATCCGTAATTCATTCTTTTTAAATTATTTTTCATTATAT; GAATATACCACAACTTGTTAATTCATCCTACCATCAATATACAGTTTGGGGCTATTATGA; ATAAAGCTGCTATGAATATTCTTACAATATCTTTCGGTGGGCATTTCTGCTGGGTACACA; CACCTACGAGGAATTGCTGGGGCAAAGAGTAGGCAAATGTTTCGTTTCAGTAGATTGTTT; TCCAGAGTGCTTGGAAACATTTTCACCTCCCCCCCCACTAGTTTTTGAACATATCACAAA; AGAACTTCTCCATTGGAAGTATTCCCTATGGTCTTGCGGAAAAAGAGGAGCTCGATGCGT; CCCCCAGGGATAAACCTCAAAGACGGGAGGAGCAGGACCAATTTCCCAAACCTACGGGCT; GGCTGGGTGGTGGGGCCTTGCTGGGCTGGCTCAACATCAATTTGGGACTGGTCCTGGAGG; GCCTCTAGTGCCCAAGATCCCTTAAGGCCCGGGTG;
• Restriction Sites: Please inquire
• ACCN: NM_014249
• Insert Size: 1800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_014249.2, NP_055064.1
• RefSeq Size: 1999 bp
• RefSeq ORF: 1233 bp
• Locus ID: 10002
• UniProt ID: Q9Y5X4
• Cytogenetics: 15q23
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Summary: This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (b) contains a longer C-terminus compared to isoform a.