IFNAR2 (NM_207585) Human Untagged Clone
SKU
SC308614
IFNAR2 (untagged)-Human interferon (alpha, beta and omega) receptor 2 (IFNAR2), transcript variant 1
$720.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | IFNAR2 |
| Synonyms | IFN-alpha-REC; IFN-R; IFNABR; IFNARB; IMD45 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | Please inquire | |
| ACCN | NM_207585 |
| Insert Size | 1500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_207585.1. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_207585.1, NP_997468.1 |
| RefSeq Size | 2898 bp |
| RefSeq ORF | 1548 bp |
| Locus ID | 3455 |
| UniProt ID | P48551 |
| Cytogenetics | 21q22.11 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Toll-like receptor signaling pathway |
| Summary | The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45. provided by RefSeq, Jul 2020 Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1 and 4 both encode isoform a. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_207585" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC218039 | IFNAR2 (Myc-DDK-tagged)-Human interferon (alpha, beta and omega) receptor 2 (IFNAR2), transcript variant 1 | 10 ug |
$719.00
|
|
| RC218039L1 | Lenti-ORF clone of IFNAR2 (Myc-DDK-tagged)-Human interferon (alpha, beta and omega) receptor 2 (IFNAR2), transcript variant 1 | 10 ug |
$1,019.00
|
|
| RC218039L2 | Lenti-ORF clone of IFNAR2 (mGFP-tagged)-Human interferon (alpha, beta and omega) receptor 2 (IFNAR2), transcript variant 1 | 10 ug |
$1,019.00
|
|
| RC218039L3 | Lenti-ORF clone of IFNAR2 (Myc-DDK-tagged)-Human interferon (alpha, beta and omega) receptor 2 (IFNAR2), transcript variant 1 | 10 ug |
$1,019.00
|
|
| RC218039L4 | Lenti-ORF clone of IFNAR2 (mGFP-tagged)-Human interferon (alpha, beta and omega) receptor 2 (IFNAR2), transcript variant 1 | 10 ug |
$1,019.00
|
|
| RG218039 | IFNAR2 (tGFP-tagged) - Human interferon (alpha, beta and omega) receptor 2 (IFNAR2), transcript variant 1 | 10 ug |
$919.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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