SLC26A5 (NM_198999) Human Untagged Clone

SKU
SC307845
SLC26A5 (untagged)-Human solute carrier family 26, member 5 (prestin) (SLC26A5), transcript variant a
  $682.00
In Stock*
Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol SLC26A5
Synonyms DFNB61; PRES
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_198999 edited
ATGGATCATGCTGAAGAAAATGAAATCCTTGCAGCAACCCAGAGGTACTATGTGGAAAGG
CCTATCTTTAGTCATCCGGTCCTCCAGGAAAGACTACACACAAAGGACAAGGTTCCTGAT
TCCATTGCGGATAAGCTGAAACAGGCATTCACATGTACTCCTAAAAAAATAAGAAATATC
ATTTATATGTTCCTACCCATAACTAAATGGCTGCCAGCATACAAATTCAAGGAATATGTG
TTGGGTGACTTGGTCTCAGGCATAAGCACAGGGGTGCTTCAGCTTCCTCAAGGCTTAGCC
TTTGCAATGCTGGCAGCTGTGCCTCCAATATTTGGCCTGTACTCTTCATTTTACCCTGTT
ATCATGTATTGTTTTCTTGGAACCTCCAGACACATATCCATAGGTCCTTTTGCTGTTATT
AGCCTGATGATTGGTGGTGTAGCTGTTCGATTAGTACCAGATGATATAGTCATTCCAGGA
GGAGTAAATGCAACCAATGGCACAGAGGCCAGAGATGCCTTGAGAGTGAAAGTCGCCATG
TCTGTGACCTTACTTTCAGGAATCATTCAGTTTTGCCTAGGTGTCTGTAGGTTTGGATTT
GTGGCCATATATCTCACAGAGCCTCTGGTCCGTGGGTTTACCACCGCAGCAGCTGTGCAT
GTCTTCACCTCCATGTTAAAATATCTGTTTGGAGTTAAAACAAAGCGGTACAGTGGAATC
TTTTCCGTGGTGTATAGTACAGTTGCTGTGTTGCAGAATGTTAAAAACCTCAACGTGTGT
TCCCTAGGCGTCGGGCTGATGGTTTTTGGTTTGCTGTTGGGTGGCAAGGAGTTTAATGAG
AGATTTAAAGAGAAATTGCCGGCGCCTATTCCTTTAGAGTTCTTTGCGGTCGTAATGGGA
ACTGGCATTTCAGCTGGGTTTAACTTGAAAGAATCATACAATGTGGATGTCGTTGGAACA
CTTCCTCTAGGGCTGCTACCTCCAGCCAATCCGGACACCAGCCTCTTCCACCTTGTGTAC
GTAGATGCCATTGCCATAGCCATCGTTGGATTTTCAGTGACCATCTCCATGGCCAAGACC
TTAGCAAATAAACATGGCTACCAGGTTGACGGCAATCAGGAGCTCATTGCCCTGGGACTG
TGCAATTCCATTGGCTCACTCTTCCAGACCTTTTCAATTTCATGCTCCTTGTCTCGAAGC
CTTGTTCAGGAGGGAACCGGTGGGAAGACACAGCTTGCAGGTTGTTTGGCCTCATTAATG
ATTCTGCTGGTCATATTAGCAACTGGATTCCTCTTTGAATCATTGCCCCAGGCTGTGCTG
TCGGCCATTGTGATTGTCAACCTGAAGGGAATGTTTATGCAGTTCTCAGATCTCCCCTTT
TTCTGGAGAACCAGCAAAATAGAGCTGACCATCTGGCTTACCACTTTTGTGTCCTCCTTG
TTCCTGGGATTGGACTATGGTTTGATCACTGCTGTGATCATTGCTCTGCTGACTGTGATT
TACAGAACACAGAGTCCAAGCTACAAAGTCCTTGGAAAGCTTCCTGAAACTGATGTGTAT
ATTGATATAGACGCATATGAGGAGGTGAAAGAAATTCCTGGAATAAAAATATTTCAAATA
AATGCACCAATTTACTATGCAAATAGCGACTTGTATAGCAATGCATTAAAACGAAAGACT
GGAGTGAACCCAGCAGTCATCATGGGAGCAAGGAGAAAGGCCATGCGGAAGTACGCTAAG
GAAGTCGGAAATGCAAATATGGCCAACGCAACTGTTGTCAAAGCAGATGCAGAAGTAGAT
GGAGAGGATGCTACCAAGCCTGAAGAAGAGGATGGTGAAGTAAAATATCCCCCAATAGTG
ATCAAAAGCACATTTCCTGAGGAAATGCAAAGATTTATGCCCCCAGGGGATAACGTCCAC
ACTGTCATTTTGGATTTCACTCAAGTCAATTTTATTGATTCTGTTGGAGTGAAAACTCTG
GCAGGGATTGTAAAAGAATATGGAGACGTCGGTATATATGTATACTTAGCAGGATGCAGT
GCACAAGTTGTGAATGACCTCACTCGGAATAGATTTTTTGAAAATCCTGCCCTATGGGAG
CTGCTGTTCCACAGCATTCATGATGCAGTTTTAGGCAGCCAACTTAGAGAGGCACTTGCT
GAACAGGAAGCCTCGGCTCCCCCTTCCCAGGAGGACTTGGAGCCCAATGCCACTCCTGCC
ACTCCTGAGGCATAG
Restriction Sites Please inquire |
ACCN NM_198999
Insert Size 2200 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_198999.1, NP_945350.1
RefSeq Size 2671 bp
RefSeq ORF 2235 bp
Locus ID 375611
UniProt ID P58743
Cytogenetics 7q22.1
Protein Families Transmembrane
Summary This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Nov 2009
Transcript Variant: This variant (a), also known as SLC26A5a, represents the longest transcript and encodes the longest isoform (a).
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Documents
Resources
"NM_198999" in other vectors (6)
SKU Description Size Price
RC216363 SLC26A5 (Myc-DDK-tagged)-Human solute carrier family 26, member 5 (prestin) (SLC26A5), transcript variant a 10 ug
$681.00
RC216363L1 Lenti ORF clone of Human solute carrier family 26, member 5 (prestin) (SLC26A5), transcript variant a, Myc-DDK-tagged 10 ug
$981.00
RC216363L2 Lenti ORF clone of Human solute carrier family 26, member 5 (prestin) (SLC26A5), transcript variant a, mGFP tagged 10 ug
$981.00
RC216363L3 Lenti ORF clone of Human solute carrier family 26, member 5 (prestin) (SLC26A5), transcript variant a, Myc-DDK-tagged 10 ug
$981.00
RC216363L4 Lenti ORF clone of Human solute carrier family 26, member 5 (prestin) (SLC26A5), transcript variant a, mGFP tagged 10 ug
$981.00
RG216363 SLC26A5 (tGFP-tagged) - Human solute carrier family 26, member 5 (prestin) (SLC26A5), transcript variant a 10 ug
$881.00

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