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MAGI3 (NM_152900) Human Untagged Clone

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SKU
SC306520
MAGI3 (untagged)-Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2
  $980.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol MAGI3
Synonyms dJ730K3.2; MAGI-3
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_152900 edited
CGTCTCGCGTCTGGGAACGGCCGGGCCCCCAGCGGGCTGTGGTCGCGGGGTGGGGGCCGG
AGCGGCGAGGCCCCCCTTACCGGGCTGCGCGGGCCGCCCAGGGCCCCCGGGCTGAGACGG
GGCCGGAGCGGCGCCCCGGCCGCCCGCGCGGGGTCTCCCCCATGGTGCAGCGGGGTTCGG
GATGTCGAAGACGCTGAAGAAGAAGAAGCACTGGCTCAGCAAGGTGCAGGAGTGCGCCGT
GTCCTGGGCCGGGCCCCCGGGCGACTTCGGCGCGGAGATCCGCGGTGGCGCGGAGCGTGG
CGAGTTCCCCTACCTGGGGCGGCTCCGCGAGGAGCCCGGCGGGGGCACCTGCTGCGTCGT
CTCGGGCAAGGCGCCCAGCCCAGGCGATGTGCTGCTGGAGGTAAACGGGACGCCTGTCAG
CGGGCTCACCAACCGGGACACCCTGGCTGTCATCCGCCACTTCCGCGAGCCCATCCGTCT
CAAGACTGTGAAACCAGGCAAAGTCATTAATAAAGATTTGCGGCATTACCTAAGTCTTCA
GTTTCAAAAAGGATCAATTGACCACAAACTGCAGCAAGTGATCAGAGATAATCTCTACTT
GAGAACCATTCCATGCACTACAAGGGCCCCCAGGGATGGAGAAGTACCAGGAGTGGATTA
TAATTTCATTTCCGTTGAACAGTTCAAAGCACTGGAAGAGAGTGGAGCATTGTTAGAAAG
TGGGACATATGATGGAAACTTCTATGGAACTCCCAAGCCTCCAGCAGAACCCAGCCCTTT
TCAGCCAGATCCAGTTGATCAAGTCCTCTTTGATAATGAGTTTGATGCAGAATCTCAAAG
AAAACGAACGACATCTGTCAGCAAGATGGAAAGAATGGATAGCTCTCTTCCTGAAGAGGA
AGAAGATGAGGACAAGGAAGCTATTAATGGCAGTGGAAACGCAGAAAACAGAGAGAGGCA
TTCTGAGTCATCTGACTGGATGAAGACTGTTCCAAGTTACAACCAAACAAATAGCTCCAT
GGACTTTAGAAATTATATGATGAGAGATGAGACTCTGGAACCACTGCCCAAAAACTGGGA
AATGGCCTACACTGACACAGGGATGATCTACTTCATTGACCACAATACCAAGACAACCAC
CTGGTTGGATCCTCGTCTTTGTAAGAAAGCCAAAGCCCCTGAAGACTGTGAAGATGGAGA
GCTTCCTTATGGCTGGGAGAAAATAGAGGACCCTCAGTATGGGACATACTATGTTGATCA
CCTTAACCAGAAAACCCAGTTTGAAAATCCAGTGGAGGAAGCCAAAAGGAAAAAGCAGTT
AGGACAGGTTGAAATTGGGTCTTCAAAACCAGATATGGAAAAATCACACTTCACAAGAGA
TCCATCCCAGCTTAAAGGTGTCCTTGTTCGAGCATCACTGAAAAAAAGCACAATGGGATT
TGGTTTTACTATTATTGGTGGAGATAGACCTGATGAGTTCCTACAAGTGAAAAATGTGCT
GAAAGATGGTCCCGCAGCTCAGGATGGGAAAATTGCACCAGGCGATGTTATTGTAGACAT
CAATGGCAACTGTGTCCTCGGTCACACTCATGCAGATGTTGTCCAGATGTTTCAATTGGT
ACCTGTCAATCAGTATGTAAACCTCACTTTATGTCGTGGTTATCCACTTCCTGATGACAG
TGAAGATCCTGTTGTGGACATTGTTGCTGCTACCCCTGTCATCAATGGACAGTCATTAAC
CAAGGGAGAGACTTGCATGAATCCTCAGGATTTTAAGCCAGGAGCAATGGTTCTGGAGCA
GAATGGAAAATCGGGACACACTTTGACTGGTGATGGTCTCAATGGACCATCAGATGCAAG
TGAGCAGAGAGTATCCATGGCATCGTCAGGCAGCTCCCAGCCTGAACTAGTGACTATCCC
TTTGATTAAGGGCCCTAAAGGGTTTGGGTTTGCAATTGCTGACAGCCCTACTGGACAGAA
GGTGAAAATGATACTGGATAGTCAGTGGTGTCAAGGCCTTCAGAAAGGAGATATAATTAA
GGAAATATACCATCAAAATGTGCAGAATTTAACACATCTCCAAGTGGTAGAGGTGCTAAA
GCAGTTTCCAGTAGGTGCTGATGTACCATTGCTTATCTTAAGAGGAGGTCCTCCTTCACC
AACCAAAACTGCCAAAATGAAAACAGATAAAAAGGAAAATGCAGGAAGTTTGGAGGCCAT
AAATGAGCCTATTCCTCAGCCTATGCCTTTTCCACCGAGCATTATCAGGTCAGGATCCCC
AAAATTGGATCCTTCTGAGGTCTACCTGAAATCTAAGACTTTATATGAAGATAAACCACC
AAACACCAAAGATTTGGATGTTTTTCTTCGAAAACAAGAGTCAGGGTTTGGCTTCAGGGT
GCTAGGAGGAGATGGACCTGACCAGTCTATATATATTGGGGCTATTATTCCCCTGGGAGC
AGCTGAGAAAGATGGTCGGCTCCGCGCAGCTGATGAACTAATGTGCATTGATGGAATTCC
TGTTAAAGGGAAATCACACAAACAAGTCTTGGACCTCATGACAACTGCTGCTCGAAATGG
CCATGTGTTACTAACTGTCAGACGGAAGATCTTCTATGGAGAAAAACAACCCGAGGACGA
CAGCTCTCAGGCCTTCATTTCAACACAGAATGGATCTCCCCGCCTGAACCGGGCAGAGGT
CCCAGCCAGGCCTGCACCCCAGGAGCCCTATGATGTTGTCTTGCAACGAAAAGAAAATGA
AGGATTTGGCTTTGTCATCCTCACCTCCAAAAACAAACCACCTCCAGGAGTTATTCCTCA
TAAAATTGGCCGAGTCATAGAAGGAAGTCCGGCTGACCGCTGTGGAAAACTGAAAGTTGG
AGATCATATCTCTGCAGTGAATGGGCAGTCCATTGTTGAACTGTCTCATGATAACATTGT
TCAGCTGATCAAAGATGCTGGTGTCACCGTCACACTAACGGTCATTGCTGAAGAAGAGCA
TCATGGTCCACCATCAGGAACAAACTCAGCCAGGCAAAGCCCAGCCCTGCAGCACAGGCC
CATGGGACAGTCACAGGCCAACCACATACCTGGGGACAGAAGTGCCCTAGAAGGTGAAAT
TGGAAAAGATGTCTCCACTTCTTACAGACATTCTTGGTCAGACCACAAGCACCTTGCACA
GCCTGACACCGCAGTAATTTCAGTTGTAGGCAGTCGGCACAATCAGAACCTTGGTTGTTA
TCCAGTAGAGCTGGAGAGAGGCCCCCGGGGCTTTGGATTCAGCCTCCGAGGGGGGAAGGA
GTACAACATGGGGCTGTTCATCCTTCGTCTTGCTGAAGATGGTCCTGCCATCAAAGATGG
CAGAATTCATGTTGGTGACCAGATTGTTGAAATCAATGGGGAACCTACACAAGGAATCAC
ACATACTCGAGCAATTGAGCTCATTCAGGCTGGTGGAAATAAAGTTCTTCTTCTTTTGAG
GCCAGGAACTGGCTTGATACCTGACCATGGTTTGGCTCCTTCCGGTCTGTGCTCCTACGT
GAAACCCGAGCAACATTAAGGCTTTCAGGGCTTTTCTTGG
Restriction Sites Please inquire |
ACCN NM_152900
Insert Size 3600 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The ORF of this clone has been fully sequenced and found to be a perfect match to NM_152900.2.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_152900.1, NP_690864.1
RefSeq Size 3504 bp
RefSeq ORF 3378 bp
Locus ID 260425
UniProt ID Q5TCQ9
Cytogenetics 1p13.2
Protein Families Druggable Genome
Protein Pathways Tight junction
Summary Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (2) uses an alternate splice site at the 5' end of the last coding exon, compared to variant 1, that results in a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 1.
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Documents
Resources
"NM_152900" in other vectors (6)
SKU Description Size Price
RC218925 MAGI3 (Myc-DDK-tagged)-Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2 10 ug
$979.00
RC218925L1 Lenti ORF clone of Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2, Myc-DDK-tagged 10 ug
$1,279.00
RC218925L2 Lenti ORF clone of Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2, mGFP tagged 10 ug
$1,279.00
RC218925L3 Lenti ORF clone of Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2, Myc-DDK-tagged 10 ug
$1,279.00
RC218925L4 Lenti ORF clone of Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2, mGFP tagged 10 ug
$1,279.00
RG218925 MAGI3 (tGFP-tagged) - Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2 10 ug
$1,179.00

file-alt Citations

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