UGT1A3 (NM_019093) Human Untagged Clone

SKU
SC304671
UGT1A3 (untagged)-Human UDP glucuronosyltransferase 1 family, polypeptide A3 (UGT1A3)
  $548.00
3 Weeks*
Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol UGT1A3
Synonyms UDPGT; UDPGT 1-3; UGT-1C; UGT1-03; UGT1.3; UGT1A3S; UGT1C
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Restriction Sites SgfI-MluI |
ACCN NM_019093
Insert Size 1605 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_019093.2
RefSeq Size 2345 bp
RefSeq ORF 1605 bp
Locus ID 54659
UniProt ID P35503
Cytogenetics 2q37.1
Protein Families Transmembrane
Protein Pathways Androgen and estrogen metabolism, Ascorbate and aldarate metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pentose and glucuronate interconversions, Porphyrin and chlorophyll metabolism, Retinol metabolism, Starch and sucrose metabolism
MW 60.3 kDa
Summary This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. Substrates of this enzyme include estrone, 2-hydroxyestrone, and metabolites of benzo alpha-pyrene. provided by RefSeq, Jul 2008
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Resources
"NM_019093" in other vectors (4)
SKU Description Size Price
RC216266 UGT1A3 (Myc-DDK-tagged)-Human UDP glucuronosyltransferase 1 family, polypeptide A3 (UGT1A3) 10 ug
$497.00
RC216266L3 Lenti ORF clone of Human UDP glucuronosyltransferase 1 family, polypeptide A3 (UGT1A3), Myc-DDK-tagged 10 ug
$797.00
RC216266L4 Lenti ORF clone of Human UDP glucuronosyltransferase 1 family, polypeptide A3 (UGT1A3), mGFP tagged 10 ug
$797.00
RG216266 UGT1A3 (tGFP-tagged) - Human UDP glucuronosyltransferase 1 family, polypeptide A3 (UGT1A3) 10 ug
$697.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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