NOVA2 (NM_002516) Human Untagged Clone

SKU
SC303210
NOVA2 (untagged)-Human neuro-oncological ventral antigen 2 (NOVA2)
  $457.00
In Stock*
Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol NOVA2
Synonyms ANOVA; NEDASB; NOVA-2; NOVA3
Vector pCMV6-XL6
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Restriction Sites Please inquire |
ACCN NM_002516
Insert Size 1479 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_002516.1, NP_002507.1
RefSeq Size 1857 bp
RefSeq ORF 1479 bp
Locus ID 4858
UniProt ID Q9UNW9
Cytogenetics 19q13.32
Summary May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA.UniProtKB/Swiss-Prot Function
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Documents
Resources
"NM_002516" in other vectors (6)
SKU Description Size Price
RC216200 NOVA2 (Myc-DDK-tagged)-Human neuro-oncological ventral antigen 2 (NOVA2) 10 ug
$686.00
RC216200L1 Lenti ORF clone of Human neuro-oncological ventral antigen 2 (NOVA2), Myc-DDK-tagged 10 ug
$986.00
RC216200L2 Lenti ORF clone of Human neuro-oncological ventral antigen 2 (NOVA2), mGFP tagged 10 ug
$986.00
RC216200L3 Lenti ORF clone of Human neuro-oncological ventral antigen 2 (NOVA2), Myc-DDK-tagged 10 ug
$986.00
RC216200L4 Lenti ORF clone of Human neuro-oncological ventral antigen 2 (NOVA2), mGFP tagged 10 ug
$986.00
RG216200 NOVA2 (tGFP-tagged) - Human neuro-oncological ventral antigen 2 (NOVA2) 10 ug
$886.00

file-alt Citations

Embryonic spinocerebellar ataxia type 37 AUUUC repeat RNA causes neurodevelopmental defects in zebrafish
Castro, Figueiredo, Loureiro et al
Dis Model Mech (2026)
Cited by 1
AI Summary: OriGene’s pCMV6-XL6-NOVA2 plasmid (SC303210) was used to clone and synthesize human NOVA2 mRNA for microinjection experiments, enabling the study of NOVA2’s role in rescuing neurodevelopmental defects in zebrafish.
Snippet: To synthesize human NOVA2 mRNA for microinjection in zebrafish, a sequence encoding fourteen histidine residues was cloned in pCMV6-XL6-NOVA2 (SC303210, Origene) at the Cterminal of NOVA2 cDNA using the IVA cloning approach (Garcia-Nafria et al., 2016),
The AUUUC repeat RNA aggregates sequester RNA-binding proteins like NOVA2 and lead to iron dyshomeostasis in spinocerebellar ataxia type 37
Figueiredo, Loureiro, Sampaio et al
bioRxiv (2025)
AI Summary: OriGene’s NOVA2 Human Untagged Clone (#SC303210) was used in this study to express full-length NOVA2 cDNA, enabling the investigation of its sequestration by AUUUC repeat RNA aggregates in spinocerebellar ataxia type 37.
Snippet: the NOVA2 Human Untagged Clone (#SC303210, Origene) vector was modified by (#SC303210, OriGene) containing the full-length NOVA2 cDNA (NM_002516) that we
Embryonic Spinocerebellar Ataxia Type 37 AUUUC Repeat RNA Causes Neurodevelopmental Defects in Zebrafish
Castro, Figueiredo, Loureiro et al
bioRxiv (2025)
Cited by 1
AI Summary: OriGene's pCMV6-XL6-NOVA2 plasmid (SC303210) was used to clone and express human NOVA2 mRNA for microinjection in zebrafish, enabling the study of NOVA2’s role in rescuing neurodevelopmental defects caused by AUUUC repeat RNA.
Snippet: To synthesize human NOVA2 mRNA for microinjection in zebrafish, a sequence encoding fourteen histidine residues was cloned in pCMV6-XL6-NOVA2 (SC303210, Origene) at the C-terminal of NOVA2 cDNA using the IVA cloning approach (Garcia-Nafria et al., 2016), for NOVA2 immunofluorescence staining with anti-histidine antibody. Amplification of NOVA2 was performed using Phusion High Fidelity DNA polymerase (NEB) with the following primers: 5’-CATCATCATCATCATCATTGAGGCCTGTGGTGTGTGCTC-3’ and 5’
Showing 1-3 of 3 papers.
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