SS18 (NM_001007559) Human Untagged Clone

SKU SC301244

SS18 (untagged)-Human synovial sarcoma translocation, chromosome 18 (SS18), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: SS18
• Synonyms: SSXT; SYT
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001007559 edited; GGCGGCAACATGTCTGTGGCTTTCGCGGCCCCGAGGCAGCGAGGCAAGGGGGAGATCACT; CCCGCTGCGATTCAGAAGATGTTGGATGACAATAACCATCTTATTCAGTGTATAATGGAC; TCTCAGAATAAAGGAAAGACCTCAGAGTGTTCTCAGTATCAGCAGATGTTGCACACAAAC; TTGGTATACCTTGCTACAATAGCAGATTCTAATCAAAATATGCAGTCTCTTTTACCAGCA; CCACCCACACAGAATATGCCTATGGGTCCTGGAGGGATGAATCAGAGCGGCCCTCCCCCA; CCTCCACGCTCTCACAACATGCCTTCAGATGGAATGGTAGGTGGGGGTCCTCCTGCACCG; CACATGCAGAACCAGATGAACGGCCAGATGCCTGGGCCTAACCATATGCCTATGCAGGGA; CCTGGACCCAATCAACTCAATATGACAAACAGTTCCATGAATATGCCTTCAAGTAGCCAT; GGATCCATGGGAGGTTACAACCATTCTGTGCCATCATCACAGAGCATGCCAGTACAGAAT; CAGATGACAATGAGTCAGGGACAACCAATGGGAAACTATGGTCCCAGACCAAATATGAGT; ATGCAGCCAAACCAAGGTCCAATGATGCATCAGCAGCCTCCTTCTCAGCAATACAATATG; CCACAGGGAGGCGGACAGCATTACCAAGGACAGCAGCCACCTATGGGAATGATGGGTCAA; GTTAACCAAGGCAATCATATGATGGGTCAGAGACAGATTCCTCCCTATAGACCTCCTCAA; CAGGGCCCACCACAGCAGTACTCAGGCCAGGAAGACTATTACGGGGACCAATACAGTCAT; GGTGGACAAGGTCCTCCAGAAGGCATGAACCAGCAATATTACCCTGATGGTCATAATGAT; TACGGTTATCAGCAACCGTCGTATCCTGAACAAGGCTACGATAGGCCTTATGAGGATTCC; TCACAACATTACTACGAAGGAGGAAATTCACAGTATGGCCAACAGCAAGATGCATACCAG; GGACCACCTCCACAACAGGGATATCCACCCCAGCAGCAGCAGTACCCAGGGCAGCAAGGT; TACCCAGGACAGCAGCAGGGCTACGGTCCTTCACAGGGTGGTCCAGGTCCTCAGTATCCT; AACTACCCACAGGGACAAGGTCAGCAGTATGGAGGATATAGACCAACACAGCCTGGACCA; CCACAGCCACCCCAGCAGAGGCCTTATGGATATGACCAGGGACAGTATGGAAATTACCAG; CAGTGAAAAAGTACTTACATTCCAGTAGCCAGTATCTATTAGCAGCCATATTGTCACCTC; AGCACTGTGGACACCTCCCTGTGAAGAGATCCTTCCATTCCATCTAGTTTTTGGAAAAAC; CTTGTGGATAAGTGGCTGTTTCATCAGTAAGCAGCCTTTGTGGATTAGTTATAAAAGGCT; TTAGTAGCTCAAAAATACTCTTGATTTCACATTTCTACTCTAGATGGCAACATTGGACAG; AAAATGCAATGACATAACCAATTTGTAATGATTTTGGAACTGTGTTTCAAATGGACTGTT; ACAGACTGAAAGGTGTGAACAGCTTTGTATGTTTATGAAGGGTAAGGGAATTTAATACTT; TTCCACAGATTTTTTTGTAAGGGGAAGAGGGAAATGTACACTTTTTACAGCAGCAATATT; TTGTATATTATGTTTATTTCATGTGGTGAATATGCAAGGCGGTACACTACGCACTGGACA; GCATCAGAAATCCTCTGTTAATGTGGACTGGAGCATGGTAGATGCTTGATTGTTTTGGTC; TCAAAATGGTGTGCTATAAAGATAAAGGTGAGGGGAAGACAAAGCACACCATATGTCCAC; TGTTCTGTTCTCATAGAGGAAATTCAAATCCCTTTTATCTATTAGATAATCAAGGGCACT; GTGATACAGTTTTGAGTAAAAAGACATTTTTTAAAAGCCTTCCAGTTTTGTGGATTAAAC; CTTTTTATAAAGATCATTTATAATACTGTTTTAAAATGTGAGGCAATAAGAATTACTTTG; TGTTGGATCTGAGGAGGCTTTGGTAAAACAGTTTCATCTAAATGAAAGTGGTAATCCTCT; TCTAAAATAGCAATAACTGAAAATGAAAGTGTTAATTTTACCTTGTTTGAGTTATCAGGG; AACTTAGTAAGTAATATCAAAGCATTTTATAAATGATATCAAAGAAGAGTCAACATTGAT; CCAGTCATTTTATTTTGTAATATTGAGGGATAATTGGTTATTAAACTGAATAGTTCAGGA; GACTTTACAAACCTTTGTTTCAACTTTCTTATCTGGAAATAATATCATTTATAAAGGGAC; ACTTTTATGTTTTTCCCTTTTTTATGTTGGTTGATATAACACAAAGAGATATTTAGGAAA; ATGCTTATTGATGAGGTTTATTCTATCTGTTTTTAAAGCACCGAGGTTGCATTCTAGATA; ACCTTGTTTATTAGCATGGCATATTTTAATCATTATTTGAGACTGTCCTGTGCCTGATTA; TTTTAGCTAAATTCAGGGAGATTGCGTGGGGCAGGAAAGCATGCATTGAAAAATTTCTAA; CCACGGTTATTTAAGCATAATCTGAAAACATCTAGCCCAAAGGTAAGTTGCTATTTTCAT; CACAGTTGCCTATGCCCAGGGAATAAGATGTATTCTTTATAATTGAATTGGTTTTTCCCA; CGTCTAACTGGAAACAAAACAGAAGGGGCGTCATAAATTTGAATAAGCAGAACATACTGT; TCTCAACATACTGTAATCAAAAGGAGGAATTTCAGTGGGTCTCTGTGTGTGTATGAGAGA; GAGAGTGTGTGTTTGTGTGTTTCAAGGTCAGAACAGGTTTTTTTGTTTTTGTTTTTTGTT; CTTTGTTTTTTTTTTTGAGATGGAGTCTTGCTCTTGTCGCCCAGGCTGGAGTGCAGTGGC; GCAATCTCAGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAGTTCTCCTGCCTCAGCC; TCCTGAGTAGCTGGGATGACAGGCACCCGCCACCACACCCAGCTAATTTTTGTACTTTTA; GTAGAGACGAGGTTTCGCCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGAT; CCACCCGCCTCGGCCTTCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCTGGCCA; GAATAGGTTTTTTCTTTCAACTTGATCAGTAGAAAATGGACATCAAGTTTGAACAGATAA; ATCATGGACAGCCTTATTGTGATTGAAATGCTTGTAGGTTCTGTGCCAATTTTCCACCAC; TGTGTACTTTGTTGCTATTTAAAACTGTATCAACTCTAACGGAAGAATAAATTATTTGTG; ATTTTAAAAAAAAAAAAAAAAAA;
• Restriction Sites: Please inquire
• ACCN: NM_001007559
• Insert Size: 3400 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001007559.1.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001007559.1, NP_001007560.1
• RefSeq Size: 3440 bp
• RefSeq ORF: 1257 bp
• Locus ID: 6760
• UniProt ID: Q15532
• Cytogenetics: 18q11.2
• Protein Families: Druggable Genome
• Summary: Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058).[UniProtKB/Swiss-Prot Function]; Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).