CLINT1 (NM_014666) Human Untagged Clone

SKU SC127470

CLINT1 (untagged)-Human clathrin interactor 1 (CLINT1), transcript variant 2

Product Data

• Type: Human Untagged Clone
• Target Symbol: CLINT1
• Synonyms: CLINT; ENTH; EPN4; EPNR
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127470 sequence for NM_014666 edited (data generated by NextGen Sequencing); ATGTTGAACATGTGGAAGGTGCGCGAGCTGGTGGACAAAGCCACCAATGTTGTTATGAAT; TATTCAGAGATCGAGTCTAAGGTTCGAGAGGCAACGAACGATGATCCTTGGGGACCTTCT; GGGCAACTCATGGGAGAGATTGCCAAGGCTACATTTATGTATGAACAATTTCCAGAACTT; ATGAACATGCTTTGGTCACGAATGTTAAAAGACAACAAAAAGAATTGGAGAAGAGTTTAT; AAGTCGTTGCTGCTCCTAGCTTACCTCATAAGGAATGGATCAGAGCGTGTTGTTACAAGT; GCCAGAGAACACATTTATGATTTACGATCCCTGGAAAATTACCACTTTGTAGATGAGCAT; GGTAAGGATCAAGGTATAAATATTCGACAGAAGGTGAAGGAATTGGTTGAATTTGCCCAG; GATGACGACAGGCTTCGTGAAGAGCGAAAGAAAGCAAAGAAGAACAAAGACAAGTATGTT; GGGGTTTCCTCAGACAGTGTTGGAGGATTCAGATACAGTGAAAGATATGATCCTGAGCCC; AAATCAAAATGGGATGAGGAGTGGGATAAAAACAAGAGTGCTTTTCCATTCAGTGATAAA; TTAGGTGAGCTGAGTGATAAAATTGGAAGCACAATTGATGACACCATCAGCAAGTTCCGG; AGGAAAGATAGAGAAGACTCTCCAGAAAGATGCAGCGACAGCGATGAGGAAAAGAAAGCG; AGAAGAGGCAGATCTCCCAAAGGTGAATTCAAAGATGAAGAGGAGACTGTGACGACAAAG; CATATTCATATCACACAGGCCACAGAGACCACCACAACCAGACACAAGCGCACAGCAAAT; CCTTCCAAAACCATTGATCTTGGAGCAGCAGCACATTACACAGGGGACAAAGCAAGTCCA; GATCAGAATGCTTCAACCCACACACCTCAGTCTTCAGTTAAGACTTCAGTGCCTAGCAGC; AAGTCATCTGGTGACCTTGTTGATCTGTTTGATGGCACCAGCCAGTCAACAGGAGGATCA; GCTGATTTATTCGGAGGATTTGCTGACTTTGGCTCAGCTGCTGCATCAGGCAGTTTCCCT; TCCCAAGTAACAGCAACAAGTGGGAATGGAGACTTTGGTGACTGGAGTGCCTTCAACCAA; GCCCCATCAGGCCCTGTTGCTTCCAGTGGCGAGTTCTTTGGCAGTGCCTCACAGCCAGCG; GTAGAACTTGTTAGTGGCTCACAATCAGCTCTAGGCCCACCTCCTGCTGCCTCAAATTCT; TCAGACCTGTTTGATCTTATGGGCTCGTCCCAGGCAACCATGACATCTTCCCAGAGTATG; AATTTCTCTATGATGAGCACTAACACTGTGGGACTTGGTTTGCCTATGTCAAGATCACAG; AATACAGATATGGTCCAGAAATCAGTCAGCAAAACCTTGCCCTCTACTTGGTCTGACCCC; AGTGTAAACATCAGCCTAGACAACTTACTACCTGGTATGCAGCCTTCCAAACCCCAGCAG; CCATCACTGAATACAATGATTCAGCAACAGAATATGCAGCAGCCTATGAATGTGATGACT; CAAAGTTTTGGAGCTGTGAACCTCAGTTCTCCATCGAACATGCTTCCTGTCCGGCCCCAA; ACTAATGCTTTGATAGGGGGACCCATGCCTATGAGCATGCCCAATGTGATGACTGGCACC; ATGGGAATGGCCCCTCTTGGAAATACTCCGATGATGAACCAGAGCATGATGGGCATGAAC; ATGAACATAGGGATGTCCGCTGCTGGGATGGGCTTGACAGGCACAATGGGAATGGGCATG; CCCAACATAGCCATGACTTCTGGAACTGTGCAACCCAAGCAAGATGCCTTTGCAAATTTC; GCCAATTTTAGCAAATAA; ; Clone variation with respect to NM_014666.3;
• Restriction Sites: Please inquire
• ACCN: NM_014666
• Insert Size: 3630 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_014666.2, NP_055481.1
• RefSeq Size: 3425 bp
• RefSeq ORF: 1878 bp
• Locus ID: 9685
• UniProt ID: Q14677
• Cytogenetics: 5q33.3
• Domains: ENTH
• Summary: This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]; Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.