UNC13B (NM_006377) Human Untagged Clone
$1,362.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | UNC13B |
| Synonyms | MUNC13; munc13-2; UNC13; Unc13h2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_006377 |
| Insert Size | 6360 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_006377.2, NP_006368.2 |
| RefSeq Size | 6328 bp |
| RefSeq ORF | 4776 bp |
| Locus ID | 10497 |
| UniProt ID | O14795 |
| Cytogenetics | 9p13.3 |
| Domains | C2, DAG_PE-bind |
| Protein Families | Druggable Genome |
| Summary | This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. provided by RefSeq, Jul 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_006377" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC219186 | UNC13B (Myc-DDK-tagged)-Human unc-13 homolog B (C. elegans) (UNC13B) | 10 ug |
$589.00
$1,361.00
|
|
| RC219186L3 | Lenti-ORF clone of UNC13B (Myc-DDK-tagged)-Human unc-13 homolog B (C. elegans) (UNC13B) | 10 ug |
$1,661.00
|
|
| RC219186L4 | Lenti-ORF clone of UNC13B (mGFP-tagged)-Human unc-13 homolog B (C. elegans) (UNC13B) | 10 ug |
$1,661.00
|
|
| RG219186 | UNC13B (tGFP-tagged) - Human unc-13 homolog B (C. elegans) (UNC13B) | 10 ug |
$1,561.00
|
|
Citations
UNC13B-A potential target gene of 9p13. 3 amplicon in prostate cancer
VESAMÄKI
Thesis (2015)
VESAMÄKI
Thesis (2015)
Snippet: For functional assays, cells were transiently transfected with UNC13B cDNA cloned in pCMV6-XL4 expression vector (OriGene Technologies, Inc.)
Showing 1-1 of 1 papers.
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