MD2 (LY96) (NM_015364) Human Untagged Clone

SKU SC125964

LY96 (untagged)-Human lymphocyte antigen 96 (LY96), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: MD2
• Synonyms: ESOP-1; ly-96; MD-2; MD2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015364 edited; GTAAAGCTTTGGAGATATTGAATCATGTTACCATTTCTGTTTTTTTCCACCCTGTTTTCT; TCCATATTTACTGAAGCTCAGAAGCAGTATTGGGTCTGCAACTCATCCGATGCAAGTATT; TCATACACCTACTGTGATAAAATGCAATACCCAATTTCAATTAATGTTAACCCCTGTATA; GAATTGAAAGGATCCAAAGGATTATTGCACATTTTCTACATTCCAAGGAGAGATTTAAAG; CAATTATATTTCAATCTCTATATAACTGTCAACACCATGAATCTTCCAAAGCGCAAAGAA; GTTATTTGCCGAGGATCTGATGACGATTACTCTTTTTGCAGAGCTCTGAAGGGAGAGACT; GTGAATACAACAATATCATTCTCCTTCAAGGGAATAAAATTTTCTAAGGGAAAATACAAA; TGTGTTGTTGAAGCTATTTCTGGGAGCCCAGAAGAAATGCTCTTTTGCTTGGAGTTTGTC; ATCCTACACCAACCTAATTCAAATTAGAATAAATTGAGTATTTAAAAAAAAAAAAAAAAA; AAAAAAAAAAAA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015364 unedited; CGTGCAGTCATTATTTGTATACGACTCATATAGGCGGCCGCGTAATTCGCCATTACGGCC; GGGGGTAAAGCTTTGGAGATATTGAATCATGTTACCATTTCTGTTTTTTTCCACCCTGTT; TTCTTCCATATTTACTGAAGCTCAGAAGCAGTATTGGGTCTGCAACTCATCCGATGCAAG; TATTTCATACACCTACTGTGATAAAATGCAATACCCAATTTCAATTAATGTTAACCCCTG; TATAGAATTGAAAGGATCCAAAGGATTATTGCACATTTTCTACATTCCAAGGAGAGATTT; AAAGCAATTATATTTCAATCTCTATATAACTGTCAACACCATGAATCTTCCAAAGCGCAA; AGAAGTTATTTGCCGAGGATCTGATGACGATTACTCTTTTTGCAGAGCTCTGAAGGGAGA; GACTGTGAATACAACAATATCATTCTCCTTCAAGGGAATAAAATTTTCTAAGGGAAAATA; CAAATGTGTTGTTGAAGCTATTTCTGGGAGCCCAGAAAAAATGCTCTTTTGCTTGGAGTT; TGTCATCCTACACCAACCTAATTCAAATTAGAATAAATTGAGTATTTAAAAAANAAAAAN; ANAAAAAAAAAAAAACCTTGTCGGCCGCCTCGGCCCTCGACTCTAGATTGCGGCCGCGGT; CATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCT; CCTGGCCCTGGAAGTTGCCACTCCAGTGCCCACCAGCCTTGTCCCAAAAAAAATAATTGC; ACCATTTTGTCCGACTAGGTGTCCCCTCATAATATTATGGGTGAAGGGGGGCGGGGTATG; AAACAAGGGGAAGTATGTAATAACAACTAATAATGTATGCAGGTTCCAATC;
• Restriction Sites: NotI-NotI
• ACCN: NM_015364
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015364.2, NP_056179.1
• RefSeq Size: 587 bp
• RefSeq ORF: 483 bp
• Locus ID: 23643
• UniProt ID: Q9Y6Y9
• Cytogenetics: 8q21.11
• Protein Families: Secreted Protein
• Protein Pathways: Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway
• Summary: This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2010]; Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).