Dermcidin (DCD) (NM_053283) Human Untagged Clone

SKU
SC125779
DCD (untagged)-Human dermcidin (DCD)
  $150.00
In Stock*
Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol Dermcidin
Synonyms AIDD; DCD-1; DSEP; HCAP; PIF
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_053283 edited
GGGACCCTAGATCCCAAGATCTCCAAGGATTCGGTGGCATACCCACTCCAGCACACAGAA
GCATGAGGTTCATGACTCTCCTCTTCCTGACAGCTCTGGCAGGAGCCCTGGTCTGTGCCT
ATGATCCAGAGGCCGCCTCTGCCCCAGGATCGGGGAACCCTTGCCATGAAGCATCAGCAG
CTCAAAAGGAAAATGCAGGTGAAGACCCAGGGTTAGCCAGACAGGCACCAAAGCCAAGGA
AGCAGAGATCCAGCCTTCTGGAAAAAGGCCTAGACGGAGCAAAAAAAGCTGTGGGGGGAC
TCGGAAAACTAGGAAAAGATGCAGTCGAAGATCTAGAAAGCGTGGGTAAAGGAGCCGTCC
ATGACGTTAAAGACGTCCTTGACTCAGTACTATAGCTGTAAGGAGAAGCTGAGAAATGAT
ACCCAGGAGCAGCAGGCTTTACGTCTTCAGCCTAAAACCTAAAAAAAAAAAAAAAAAAAA
AATTTAAAACAGCTATTAAACTGAAAGCATCTGGAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_053283 unedited
GGTCAGGATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCCATTACGGGCCGGG
GACCCTANATCCCAANATCTCCAGGGTTCGGTGGCGTACCCACTCCAGCACACAGAAGCA
TGAGGTTCATGACTCTCCTCTTCCTGACAGCTCTGGCAGGAGCCCTGGTCTGTGCCTATG
ATCCAGAGGCCGCCTCTGCCCCAGGATCGGGGAACCCTTGCCATGAAGCATCAGCAGCTC
AAAAGGAAAATGCAGGTGAAGACCCAGGGTTAGCCAGACAGGCACCAAAGCCAAGGAAGC
AGAGATCCAGCCTTCTGGAAAAAGGCCTAGACGGAGCAAAAAAAGCTGTGGGGGGACTCG
GAAAACTAGGAAAAGATGCAGTCGAAGATCTAGAAAGCGTGGGTAAAGGAGCCGTCCATG
ACGTTAAAGACGTCCTTGACTCAGTACTATAGCTGTAAGGAGAAGCTGAGAAATGATACC
CAGGAGCAGCAGGCTTTACGTCTTCAGCCTAAAACCTAAAAAAAAAAAAAAAAAAAAAAT
TTAAAACAGCTATTAAACTGAAAGCATCTGGAAAAAAAAAAAANNAAAAAAAAAAAAAAA
ACATGGTCGGCCGCCTCGGCCCTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCT
GAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCGTCTCCTGGGCCTGGAAG
GTGCCACTCCGTGCCCACCAGCCTTGGCCTATAAAATTAAGTTGCATCATTTTGTCTGAC
TAGGTGTCCTTCTAAATATTATGGGGTGAGGGGGGTNGGGTTTGAACCAGGGGCAATTTT
GAAAAACACCCGGAGGGGCTGCGGGGGCTATTGGAAACAAGTGGAGTGGGGGGGCCATCT
TGGCTATGGGATCTCCCCTCTGGGGTCAACCATT
Restriction Sites Please inquire |
ACCN NM_053283
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_053283.1, NP_444513.1
RefSeq Size 458 bp
RefSeq ORF 333 bp
Locus ID 117159
UniProt ID P81605
Cytogenetics 12q13.2
Protein Families Secreted Protein
Summary This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Oct 2014
Transcript Variant: This variant (1) lacks an alternate exon in the 3' coding region, resulting in a frameshift compared to variant 2. The encoded isoform (1) has a distinct C-terminus , and is shorter, compared to isoform 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
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Documents
Resources
"NM_053283" in other vectors (6)
SKU Description Size Price
RC209352 DCD (Myc-DDK-tagged)-Human dermcidin (DCD) 10 ug
$150.00
RC209352L1 Lenti ORF clone of Human dermcidin (DCD), Myc-DDK-tagged 10 ug
$450.00
RC209352L2 Lenti ORF clone of Human dermcidin (DCD), mGFP tagged 10 ug
$450.00
RC209352L3 Lenti ORF clone of Human dermcidin (DCD), Myc-DDK-tagged 10 ug
$450.00
RC209352L4 Lenti ORF clone of Human dermcidin (DCD), mGFP tagged 10 ug
$450.00
RG209352 DCD (tGFP-tagged) - Human dermcidin (DCD) 10 ug
$489.00

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