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SOCS5 (NM_144949) Human Untagged Clone

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SKU
SC124288
SOCS5 (untagged)-Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 2
  $500.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol SOCS5
Synonyms CIS6; Cish5; CISH6; SOCS-5
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for NM_144949, the custom clone sequence may differ by one or more nucleotides


ATGGATAAAGTGGGAAAAATGTGGAATAACTTCAAATACAGGTGTCAGAATCTCTTCGGTCATGAGGGAG
GAAGCCGTAGTGAAAATGTGGACATGAACTCCAACAGATGTTTGTCTGTCAAAGAGAAAAACATCAGCAT
AGGAGACTCAACTCCTCAGCAACAAAGCAGTCCCTTAAGAGAAAATATTGCCTTACAACTGGGATTAAGC
CCTTCGAAGAATTCTTCAAGGAGAAATCAAAATTGTGCCACAGAAATCCCTCAAATTGTTGAAATAAGCA
TCGAAAAGGATAATGATTCTTGTGTTACCCCAGGAACAAGACTTGCACGAAGAGATTCCTACTCTCGACA
TGCTCCATGGGGTGGGAAGAAAAAACATTCCTGTTCTACAAAGACCCAGAGTTCATTGGATGCTGATAAA
AAGTTTGGTAGAACTCGAAGTGGACTTCAAAGGAGAGAGAGGCGCTACGGCGTAAGTTCTGTACACGACA
TGGACAGTGTTTCCAGCAGAACTGTAGGAAGTCGCTCTCTAAGACAGAGGTTGCAGGATACTGTGGGCTT
GTGTTTTCCCATGAGAACTTACAGCAAGCAGTCAAAGCCTCTCTTTTCCAATAAAAGAAAAATCCATCTC
TCTGAATTAATGCTTGAGAAATGCCCTTTTCCTGCTGGCTCAGATTTAGCCCAAAAATGGCATTTGATTA
AACAGCATACAGCTCCTGTGAGCCCACATTCAACATTTTTTGATACATTTGATCCATCTTTGGTTTCTAC
AGAAGATGAAGAAGATAGGCTTAGAGAGAGAAGGCGGCTTAGTATTGAAGAAGGGGTTGATCCCCCTCCC
AATGCACAAATACATACATTTGAAGCTACTGCACAGGTTAATCCATTATATAAACTGGGACCAAAATTAG
CTCCTGGAATGACTGAAATAAGTGGGGACAGTTCTGCAATTCCACAAGCTAATTGTGACTCGGAAGAGGA
TACAACCACCCTGTGTTTGCAGTCACGGAGGCAGAAGCAGCGTCAGATATCTGGAGACAGCCATACCCAT
GTTAGCAGACAGGGAGCTTGGAAAGTCCACACACAGATTGATTACATACACTGCCTCGTGCCTGATTTGC
TTCAAATTACAGGGAATCCCTGTTACTGGGGAGTGATGGACCGTTATGAAGCAGAAGCCCTTCTCGAAGG
GAAACCTGAAGGCACGTTTTTGCTCAGGGACTCTGCGCAAGAGGACTACCTCTTCTCTGTGAGCTTCCGC
CGCTACAACAGATCCCTGCATGCCCGAATTGAGCAGTGGAATCACAACTTTAGTTTCGACGCCCATGACC
CGTGTGTATTTCACTCCTCCACTGTAACGGGACTTTTAGAACATTATAAAGATCCCAGTTCGTGCATGTT
TTTTGAACCATTGCTTACTATATCACTAAATAGGACTTTCCCTTTTAGCCTGCAGTATATCTGTCGCGCG
GTAATCTGCAGGTGCACTACGTATGATGGAATTGATGGGCTCCCTCTACCCTCAATGTTACAGGATTTTT
TAAAAGAGTATCATTATAAACAAAAAGTTAGAGTTCGCTGGTTGGAACGAGAACCAGTCAAGGCAAAGTA
A

5' Read Nucleotide Sequence
>OriGene 5' read for NM_144949 unedited
GGTGTCAAATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGCGGGGG
CATCCGGCGGAGCTGGGGTCCCCGGGCTCCGTCCGGAGGAAGCGACGCTGCGCTCGCTGG
GCAGTCGGAGGGGACGGGACGCACCGGAGGGCAGGCGGACTCGCCCTGTCGGTGACTGCG
CCGTCCGGGCCCGTCCTGCCTGGCCGCAGGTGCCCTGGATGAGGCCGCCCCGCGCGCCCC
AAACGATTTTATAATCAATGGATAAAGTGGGAAAAATGTGGAATAACTTCAAATACAGGT
GTCAGAATCTCTTCGGTCATGAGGGAGGAAGCCGTAGTGAAAATGTGGACATGAACTCCA
ACAGATGTTTGTCTGTCAAAGAGAAAAACATCAGCATAGGAGACTCAACTCCTCAGCAAC
AAAGCAGTCCCTTAAGAGAAAATATTGCCTTACAACTGGGATTAAGCCCTTCGAAGAATT
CTTCAAGGAGAAATCAAAATTGTGCCACAGAAATCCCTCAAATTGTTGAAATAAGCATCG
AAAAGGATAATGATTCTTGTGTTACCCCAGGAACAAGACTTGCACGAAGAGATTCCTACT
CTCGACATGCTCCATGGGGTGGGAAGAAAAAACATTCCTGTTCTACAAAGACCCAGAGTT
CATTGGATGCTGATAAAAAGTTTGGTAGAACTCGAAGTGGACTTCAAAGGAGAGAGAGGC
GCTACGGCGTAAGTTCTGTACACGACATGGACAGTGTTTCCAGCAGAACTGTAGGAAGTC
GCTCTCTAGAACAGAGTGCAGGATACTGTGGGCTTGTGTTTTCCCATGAGAACTTTACAG
CAGCAGTCAAAGCCTCTCTTTTTCCATAAAAAGAAAATTCATCTCTCTGAATAATGCTTG
AGAAATGCCTTTTNCTGCTGGCTCAGATTNAGCCCAAATG
3' Read Nucleotide Sequence
>OriGene 3' read for NM_144949 unedited
ACTATGGAACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTCATGCTG
GTGATTTTTCTTTTTTAAAATGTAAGCCACTAATATTTTAAGACAAAAATTTAAACCAAA
AATTGCATATTAATATTATACACAAACTGAAACATGTGACTTTTAGCACAGTGTATACAT
GCTTACATAAACTCAAACACATTTAAAACAATTTCCATTTAACATATGAAAGTTTTGAAA
TACATAAAAGCATTAATACTTTCTATAAAACTACAGTTAGAACATCAATTTGCTACAAGC
ATATAAAAACATCAAGTGCTTTCTTGGAGTTTCAAGTTTCCTCTCTAAAACACAATCTTG
CTCACATATATAGTCCTTTTCCAATAATCAGTATGAACTTTTCTTTTTCTCAAGAGGTTT
ATTTTCCAGGTACATTATAAGCTCAAGAAAAAAGACCCAACAATTAGGCAATATAATTAT
GTCATAACAACTTAATTGCACATAATGCTTTAAAGTAGGTTTGGATGAAGTTCTCAAACA
CTTTGGTATATGATCTTCAGGGACTTTAATTAGAAACAACAGAAATTATAAGTCCCTTCA
ATCCCCATTTTGCTTTAAAAGGGACAAGTCTTTGGTTAAAGTTCTACATTTTGGGCATTT
ATTTTTAATTAGATGGTCCCCAAACAATAAATGTACTGATCTATACAAATTCACAGACTT
ATTTACCTGCTTCTGAGCAGTGGGAGTTACAGAACTCATTACTATATATGTCATGGGAAG
TTTCAATCTTCATTTATAGCAGAGAATCAAAGGTTATTACTTCTCTGTCAGTTTCTGTTA
TACCTAACTGTCAGTATTTGCAGTAACTACGATCTGTTCCCAGTTTATATTATGACTGAT
AGATGNGAGCATTAATTTAAGTAGCTATTCTGATAGTCATATAGACTGTCATAC
Restriction Sites NotI-NotI |
ACCN NM_144949
Insert Size 4700 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_144949.2, NP_659198.1
RefSeq Size 4510 bp
RefSeq ORF 1611 bp
Locus ID 9655
UniProt ID O75159
Cytogenetics 2p21
Domains SH2, SOCS
Protein Families Druggable Genome
Protein Pathways Jak-STAT signaling pathway
Summary The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. provided by RefSeq, Jul 2008
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein.
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Documents
Resources
"NM_144949" in other vectors (4)
SKU Description Size Price
RC206267 SOCS5 (Myc-DDK-tagged)-Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 2 10 ug
$499.00
RC206267L3 Lenti ORF clone of Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 2, Myc-DDK-tagged 10 ug
$799.00
RC206267L4 Lenti ORF clone of Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 2, mGFP tagged 10 ug
$799.00
RG206267 SOCS5 (tGFP-tagged) - Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 2 10 ug
$489.00 $699.00

file-alt Citations

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