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ACMSD (NM_138326) Human Untagged Clone

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SKU
SC123129
ACMSD (untagged)-Human aminocarboxymuconate semialdehyde decarboxylase (ACMSD)
  $686.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol ACMSD
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_138326 edited
GGGGAGTTTTCACAAAGGTCTCTTGATATCAAAACTTCTTTCCTTGCATGCTTCTCTGAT
CCTGTGGAGATGAAAATTGACATCCATAGTCATATTCTACCAAAAGAATGGCCAGATCTA
AAAAAGACCCTGAGACAAGGATTCAGATGCAAGTAGTTTGCTTTGGAGGTGATCCCAGGA
AACACCAGTAGAGTGAGGAAGTGAGACAGGGAAAACAGGGCAGCCAGTGAAAGAGGTTTG
GCTACGGAGGCTGGGTGCAGCTCCAACACCACAGCAAGGGAGAAGCAAAGTTGTTGAAAG
ATGGGAAAGTCTTCAGAGTGGTGCGAGAGAATTGCTGGGATCCAGAAGTTCGTATTAGAG
AAATGGACCAAAAAGGCCAAACCTGAGGACACTTTAAACCTGTGCCAGCTTTTAAACAAC
GACCTTGCCAGCACCGTTGTGAGCTACCCCAGGAGGTTCGTGGGTCTGGGGACGTTGCCC
ATGCAGGCCCCTGAGCTGGCGGTCAAGGAGATGGAGCGCTGTGTGAAAGAGCTGGGCTTT
CCCGGGGTCCAAATTGGCACCCACGTCAACGAGTGGGACCTGAACGCGCAGGAGCTCTTT
CCTGTCTATGCGGCAGCCGAAAGGCTGAAGTGTTCCCTGTTCGTGCATCCCTGGGACATG
CAGATGGATGGACGAATGGCCAAATACTGGCTCCCTTGGCTTGTAGGAATGCCAGCAGAG
ACCACCATAGCCATTTGCTCCATGATCATGGGTGGAGTATTTGAGAAGTTTCCCAAACTG
AAAGTGTGTTTCGCACATGGTGGTGGTGCCTTCCCCTTCACAGTGGGAAGAATCTCCCAT
GGATTCAGCATGCGCCCAGATCTGTGTGCCCAGGACAACCCCATGAACCCGAAGAAATAC
CTTGGTTCCTTTTACACAGATGCTTTGGTTCATGATCCTCTGTCCCTCAAGCTGTTAACA
GATGTCATAGGAAAGGATAAAGTCATTTTGGGAACCGATTACCCCTTTCCACTAGGTGAG
CTGGAACCTGGGAAACTAATAGAGTCCATGGAAGAATTTGATGAAGAAACAAAGAATAAA
CTCAAAGCCGGCAATGCCCTGGCATTTTTGGGTCTTGAGAGAAAACAATTTGAATGACTG
AATTTACTACAAAGGCAAACTTTCAAAAGGATATCTCATTTTTGTTTCTAAATATGTATC
AACAGGTATCAACAAAATCCTATTTTGAACTATTTTACTCAGAAATGAATGTCCCAAATA
TCCTAAATTATTCATAATAAAAATGATTTGTAAGTGTTTTCATTCTGAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_138326 unedited
CACGTCAAATATTGTATACGACTCATATAGGGCGGCCGCGAATTCGCCATTACGGCCGGG
GAGTTTTCACAAAGGTCTCTTGATATCAAAACTTCTTTCCTTGCATGCTTCTCTGATCCT
GTGGAGATGAAAATTGACATCCATAGTCATATTCTACCAAAAGAATGGCCAGATCTAAAA
AAGACCCTGAGACAAGGATTCAGATGCAAGTAGTTTGCTTTGGAGGTGATCCCAGGAAAC
ACCAGTAGAGTGAGGAAGTGAGACAGGGAAAACAGGGCAGCCAGTGAAAGAGGTTTGGCT
ACGGAGGCTGGGTGCAGCTCCAACACCACAGCAAGGGAGAAGCAAAGTTGTTGAAAGATG
GGAAAGTCTTCAGAGTGGTGCGAGAGAATTGCTGGGATCCAGAAGTTCGTATTAGAGAAA
TGGACCAAAAAGGCCAAACCTGAGGACACTTTAAACCTGTGCCAGCTTTTAAACAACGAC
CTTGCCAGCACCGTTGTGAGCTACCCCAGGAGGTTCGTGGGTCTGGGGACGTTGCCCATG
CAGGCCCCTGAGCTGGCGGTCAAGGAGATGGAGCGCTGTGTGAAAGAGCTGGGCTTTCCC
GGNGTCCAAATTGGCACCCACGTCAACGAGTGGGACCTGAACGCGCAGGAGCTCTTTCCT
GTCTATGCGGCAGCCGAAAGGCTGAAGTGTTCCCTGTTCGTGCATCCCTGGGACATGCAG
ATGGATGGACGAATGGCCAAATACTGGCTCCCTTGGCTTGTANGAATGCCAGCAGAGACC
ACCATAGCCATTTGCTCCATGATCATGGGTGGAGTATTTGAGAAGTTTCCCAACTGAAAG
TGTGTTTCCACATGGTGGTGGTGCTTTCCCCTTCCAGTGGGAAGATCTCCATGGATTCGC
ATGCGCCCAGTCTGTGC
Restriction Sites Please inquire |
ACCN NM_138326
Insert Size 1337 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_138326.1, NP_612199.1
RefSeq Size 1337 bp
RefSeq ORF 1278 bp
Locus ID 130013
UniProt ID Q8TDX5
Cytogenetics 2q21.3
Protein Families Transmembrane
Protein Pathways Metabolic pathways, Tryptophan metabolism
Summary The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.supplied by OMIM, Oct 2004
Transcript Variant: This variant (1) encodes the longer isoform (1).
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Documents
Resources
"NM_138326" in other vectors (5)
SKU Description Size Price
RC210656 ACMSD (Myc-DDK-tagged)-Human aminocarboxymuconate semialdehyde decarboxylase (ACMSD) 10 ug
$686.00
RC210656L3 Lenti ORF clone of Human aminocarboxymuconate semialdehyde decarboxylase (ACMSD), Myc-DDK-tagged 10 ug
$986.00
RC210656L4 Lenti ORF clone of Human aminocarboxymuconate semialdehyde decarboxylase (ACMSD), mGFP tagged 10 ug
$986.00
RG210656 ACMSD (tGFP-tagged) - Human aminocarboxymuconate semialdehyde decarboxylase (ACMSD) 10 ug
$886.00
SC317515 ACMSD (untagged)-Human aminocarboxymuconate semialdehyde decarboxylase (ACMSD) 10 ug
$686.00

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