SOX8 (NM_014587) Human Untagged Clone

SKU SC122819

SOX8 (untagged)-Human SRY (sex determining region Y)-box 8 (SOX8)

Product Data

• Type: Human Untagged Clone
• Target Symbol: SOX8
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014587 edited; GGCGAGGGTCGGGGCCACCGCGCGGCGACCTCGGGTCCCGGAGCGACCGCAGGGCAGCCC; CGGGCGCCGGCCCCGGTGCGCGTCTCCTGTGCGCGCCCCTCCGCGCGCGGCCCCGATGCT; GGACATGAGCGAGGCCCGCTCCCAGCCGCCCTGCAGCCCGTCCGGCACCGCCAGCTCCAT; GTCGCACGTGGAGGACTCGGACTCGGACGCGCCGCCGTCTCCCGCCGGCTCCGAGGGCCT; GGGCCGCGCGGGGGTCGCGGTGGGGGGCGCCCGGGGCGACCCGGCGGAGGCGGCGGACGA; GCGCTTCCCGGCCTGCATCCGCGACGCCGTGTCGCAGGTGCTCAAGGGCTACGACTGGAG; TCTGGTGCCCATGCCGGTGCGCGGCGGCGGCGGCGGCGCGCTCAAAGCCAAGCCGCATGT; GAAGCGGCCCATGAACGCATTCATGGTGTGGGCGCAGGCGGCGCGCCGCAAGCTGGCCGA; CCAGTACCCGCACCTGCACAACGCCGAGCTCAGCAAGACGCTGGGCAAGCTGTGGCGCTT; GCTGAGCGAGAGCGAGAAGCGGCCCTTCGTGGAGGAGGCAGAGCGCCTTCGCGTGCAGCA; CAAGAAGGACCACCCCGACTACAAGTACCAGCCACGGCGCAGGAAGAGCGCCAAAGCCGG; CCACAGCGACTCCGACTCGGGCGCGGAGCTGGGACCCCACCCTGGCGGCGGTGCCGTGTA; CAAGGCTGAAGCAGGGCTTGGAGATGGGCACCACCATGGCGACCACACAGGGCAGACCCA; CGGGCCGCCCACCCCGCCCACCACCCCCAAGACGGAGCTGCAGCAGGCGGGCGCCAAGCC; GGAGCTGAAGCTGGAGGGACGCCGGCCGGTGGACAGCGGGCGCCAGAACATCGACTTCAG; CAACGTGGACATCTCGGAGCTCAGCAGCGAGGTCATGGGCACCATGGACGCCTTCGACGT; CCACGAGTTCGACCAGTACCTGCCCCTGGGCGGCCCCGCCCCACCCGAGCCGGGCCAGGC; CTACGGGGGCGCCTACTTCCACGCCGGGGCGTCCCCCGTGTGGGCCCACAAGAGTGCCCC; GTCGGCCTCCGCGTCGCCCACCGAGACGGGTCCCCCACGGCCGCACATCAAGACGGAGCA; GCCGAGCCCCGGCCACTACGGCGACCAGCCCCGAGGCTCGCCCGACTACGGTTCCTGCAG; CGGCCAGTCCAGCGCCACCCCGGCCGCCCCCGCCGGCCCCTTCGCCGGCTCACAGGGCGA; CTATGGCGACCTGCAGGCCTCCAGCTACTATGGTGCCTACCCTGGCTACGCACCCGGCCT; CTACCAGTACCCCTGCTTCCACTCGCCGCGCCGGCCCTACGCCTCACCCCTGCTCAACGG; CCTGGCCCTGCCGCCCGCCCACAGCCCCACCAGTCACTGGGACCAGCCGGTGTACACCAC; CCTGACCAGGCCCTGAGGGCCCAGCCGCGGGGAGGGACTCGCAGGCGTCAGGGGGCAGCC; TTGTCCCGGCCCAGTGTGTGTGACCGGGGCGGGAGGGGCCCCAGTGGCTGAGCTCCAAGT; GCCTGCTGAAGTCTGCAGGGAAACACGCTTGCTGCCCGTGGCCCTCGGCCTCCAGATGGC; CACACCTCTGCCGACGACGGACCAGCTCCCTCTCCCTTCTATCTTTCTTTTTGAGGTGGT; GGGATTATTCCACAAAGAAGGGCTGCCGTTTGGTCCCTCTTCTGTGAGGACTGGCGGCAC; CAGCACCTTCGCTTTGCATCTCGGTAGAGGAGAAACGGCAGCACAGCCCAAGGACCAAAG; GAGGGGGTGGCAGGGGCCTTGCAGGGCGCTGTGAGGTCCAGGCCGGTCTTGGCGCCGAGA; GCCCCTGCACTCAAGGCCACATTCCCTCGACAACGGCTGCACGGGCTGTCCGGGATCCGG; GGTGTCTGTCCGCAGACTGGGATGAGTCTACTCGAGCATCTCCGGGACCTGCCTGTCAGA; TCTGAGGTGTCTCCTTGCTGGCAGAGTGCGCTCACGCGAGGGCTGGCTGTGATGAACACA; TCTCTCTTTTATTTTTATGTTTTTGATAATTTTTATTTTTGAAGCTTAAATGTGTTTCTT; CTGAAAGCTGTTAAAGATGTATTTATGTTCTGTGTTATTTTATCTTTAATTAATGAGGTA; ATTCGGGCAAAGAGTAGAATTTAAGACAAAACGGAAGCTGGGAAGCTTCCCTTGAGGGCA; GGCAGGAGGTGGAGTTGCAGCTGTTGGCCGGCATCACGTTGCTCGTTGCTCGGCTTATGG; GAGGCCGCCCTGGAGGGCCCGGAGGTCCCAAGGTCCCTGGGAGGACTGGGCCCCTCATGC; CTCGAGCTTGGCAACCGAAAACCCGAGGGAGGAGAAGGGACCTGCCTTGTGACATCTCTG; ATCAGGTTGGGGTGCCCCAGCACCCAGTACTAGTTTGGGGTTTGGGAAGCAGGACTCCGT; CCCTGTCCCCGACTGTGCCACGTGGTAGGACACATAGGACACAGGAATTCCTGGGTCCTT; GCCCATGACTGTGCCATGTGGTAGGACACAGGACACAGGAATTCCTGGAAAGTGGTGGCT; TCAGAAGTGATCTTGGCTCGCAGGCACCAGTGCCACCTACCAAGCTGTGAAACTAAACCT; TCTCCACTAAACGTCGTTAGGGCCTCAGTTCTAGACGAGTCATACCTGATTCACCTGCAC; TGCTTCCCCCGTGTGCTGAGCATAGAGCATACAATAGCGCCTACTTCACGGAAACTTGTG; CCTTTAAACTTTGTAAACTTAAACACAGCCGAGAAGTTGCTTCTTTGTACTTTTTCTACT; TTTCCTACTTTTTTGTAGAAAAAAAAGATAATGCCTCTGCTTCTATTTCTCTGGGGGTGG; GGGTGGGGGCCGGGAGCCGTCGCAGACCCGTTTCATGCAGCGTCTCCCTCGGCACCGCGT; TCGGAGGACGCACCCTCACTCCCCTGCTGCCTTCACTCCTTTCTGACCAAGCAACGCTAA; CTTTTGTACAGATCGATTTGATAAAATTAAACAAAGTGCTTTTTATGGAAAAAAAAAAAA; AAAAAAAAA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014587 unedited; NCCCCGTTCAGATTTGTAAACGACTCATATAGGGCGGCCGCGAATCANATCTGGTACCGG; TCCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGGGCGAGGGTCGGGGCCACCGCGC; GGCGACCTCGGGTCCCGGAGCGACCGCAGGGCAGCCCCGGGCGCCGGCCCCGGTGCGCGT; CTCCTGTGCGCGCCCCTCCGCGCGCGGCCCCGATGCTGGACATGAGCGAGGCCCGCTCCC; AGCCGCCCTGCAGCCCGTCCGGCACCGCCAGCTCCATGTCGCACGTGGAGGACTCGGACT; CGGACGCGCCGCCGTCTCCCGCCGGCTCCGAGGGCCTGGGCCGCGCGGGGGTCGCGGTGG; GGGGCGCCCGGGGCGACCCGGCGGAGGCGGCGGACGAGCGCTTCCCGGCCTGCATCCGCG; ACGCCGTGTCGCAGGTGCTCAAGGGCTACGACTGGAGTCTGGTGCCCATGCCGGTGCGCG; GCGGCGGCGGCGGCGCGCTCAAAGCCAAGCCGCATGTGAAGCGGCCCATGAACGCATTCA; TGGTGTGGGCGCAGGCGGCGCGCCGCAAGCTGGCCGACCAGTACCCGCACCTGCACAACG; CCGAGCTCAGCAAGACGCTGGGCAAGCTGTGGCGCTTGCTGAGCGAGAGCGAGAAGCGGC; CCTTCGTGGAGGAGGCAGAGCGCCTTCGCGTGCAGCACAAGAAGGACCACCCCGACTACA; AGTACCAGCCACGGCGCAGGAAGAGCGCCAAAGCCGGCCACAGCGACTCCGACTCGGGCG; CGGAGCTGGGACCCCACCCTGGCGGCNGTGCCGTGTACAAGGCTGAAGCAGGNCTTGGAG; ATGGGCACCACCATGGCGACCACACAGGGCAGACCCACGGGCCGNCCACCCCGCCNACCA; CCCCCAAGACGG;
• Restriction Sites: Please inquire
• ACCN: NM_014587
• Insert Size: 3069 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_014587.2, NP_055402.2
• RefSeq Size: 3069 bp
• RefSeq ORF: 1341 bp
• Locus ID: 30812
• UniProt ID: P57073
• Cytogenetics: 16p13.3
• Protein Families: Transcription Factors
• Summary: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the cognitive disability found in an alpha-thalassemia-related syndrome (ART-16). This protein is also highly expressed in the majority of human hepatocellular carcinomas and promotes cellular proliferation and enhanced tumor growth. [provided by RefSeq, Jul 2017]