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CTRB1 (NM_001906) Human Untagged Clone

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SKU
SC122612
CTRB1 (untagged)-Human chymotrypsinogen B1 (CTRB1)
  $300.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol CTRB1
Synonyms CTRB
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_001906 edited
GGGACCGGCAGACAGGCGTCCTACACCCCTGCCAGCGGCACCATGGCTTTCCTCTGGCTC
CTCTCCTGCTGGGCCCTCCTGGGTACCACCTTCGGCTGCGGGGTCCCCGCCATCCACCCT
GTGCTCAGCGGCCTGTCCAGGATCGTGAATGGGGAGGACGCCGTCCCCGGCTCCTGGCCC
TGGCAGGTGTCCCTGCAGGACAAAACCGGCTTCCACTTCTGCGGGGGCTCCCTCATCAGC
GAGGACTGGGTGGTCACCGCTGCCCACTGCGGGGTCAGGACCTCCGACGTGGTCGTGGCT
GGGGAGTTTGACCAGGGCTCTGACGAGGAGAACATCCAGGTCCTGAAGATCGCCAAGGTC
TTCAAGAACCCCAAGTTCAGCATTCTGACCGTGAACAATGACATCACCCTGCTGAAGCTG
GCCACACCTGCCCGCTTCTCCCAGACAGTGTCCGCCGTGTGCCTGCCCAGCGCCGACGAC
GACTTCCCCGCGGGGACACTGTGTGCCACCACAGGCTGGGGCAAGACCAAGTACAACGCC
AACAAGACCCCTGACAAGCTGCAGCAGGCAGCCCTGCCCCTCCTGTCCAATGCCGAATGC
AAGAAGTCCTGGGGCAGGAGGATCACCGACGTGATGATCTGTGCCGGGGCCAGTGGCGTC
TCCTCCTGCATGGGCGACTCTGGCGGTCCCCTGGTCTGCCAAAAGGATGGAGCCTGGACC
CTGGTGGGCATTGTGTCCTGGGGCAGCGACACCTGCTCCACCTCCAGCCCTGGCGTGTAC
GCCCGTGTCACCAAGCTCATACCTTGGGTGCAGAAGATCCTGGCTGCCAACTGAGCCCGC
GGCTCCCTCCGACCCTGCTCCCCACAGAGCCTCAGTAAACCCATGAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_001906 unedited
TTCANCATTTGTAATACGACTTACTATAGGGCGGCACGCGAATTCGCCATTACGGCCGGG
GGGGACCGGCAGACAGGCGTCCTACACCCCTGCCAGCGGCACCATGGCTTTCCTCTGGCT
CCTCTCCTGCTGGGCCCTCCTGGGTACCACCTTCGGCTGCGGGGTCCCCGCCATCCACCC
TGTGCTCAGCGGCCTGTCCAGGATCGTGAATGGGGAGGACGCCGTCCCCGGCTCCTGGCC
CTGGCAGGTGTCCCTGCAGGACAAAACCGGCTTCCACTTCTGCGGGGGCTCCCTCATCAG
CGAGGACTGGGTGGTCACCGCTGCCCACTGCGGGGTCAGGACCTCCGACGTGGTCGTGGC
TGGGGAGTTTGACCAGGGCTCTGACGAGGAGAACATCCAGGTCCTGAAGATCGCCAAGGT
CTTCAAGAACCCCAAGTTCAGCATTCTGACCGTGAACAATGACATCACCCTGCTGAAGCT
GGCCACACCTGCCCGCTTCTCCCAGACAGTGTCCGCCGTGTGCCTGCCCAGCGCCGACGA
CGACTTCCCCGCGGAGACACTGTGTGCCACCACAGGCTGGGGCAAGACCAAGTACAACGC
CAACAAGACCCCTGACAAGCTGCAGCAAGCAGCCCTGCCCCTCCTGTCCAATGCCGAATG
CAAGAAGTCCTGGGGCANNGAGATCACCGACGTGATGATCTGTGCCGAGGCCAGTGGCGT
CTCCTCCTGCATGAGCGACTCTGGCAGTCCCCTGGTCTGCCAAAAGATGGAGCCTGNACC
CTGGTGGGCATTGTGTCCTGGGGCAGCGACACCTGCTTCACCTNCAGCCCTGACGTGTAC
GCCCGTGTCACCAGCTCATACCTTGGGTGCAGAAGATACTGGCTGGCACTGAGCCCGAGC
TNCCTCGGACCTGCTCCAACGAGCCTAATAACCCC
Restriction Sites Please inquire |
ACCN NM_001906
Insert Size 915 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001906.2, NP_001897.2
RefSeq Size 872 bp
RefSeq ORF 792 bp
Locus ID 1504
UniProt ID P17538
Cytogenetics 16q23.1
Protein Families Druggable Genome, Protease, Secreted Protein, Transmembrane
Summary This gene encodes a member of the serine protease family of enzymes and forms a principal precursor of the pancreatic proteolytic enzymes. The encoded preproprotein is synthesized in the acinar cells of the pancreas and secreted into the small intestine where it undergoes proteolytic activation to generate a functional enzyme. This CTRB1 gene is located head-to-head with the related CTRB2 gene. Some human populations have an alternate haplotype which inverts a 16.6 Kb region containing portions of intron 1, exon 1, and the upstream sequence of the CTRB1 and CTRB2 genes. In this inversion haplotype exon 1 and flanking sequence is swapped in CTRB1 and CTRB2. This inversion is associated with differential gene expression and increased risk for chronic pancreatitis. The GRCh38 assembly represents the minor allele for SNP rs8048956 of the CTRB1 gene. SNP rs8048956 in intron 1 of the CTRB2 gene is diagnostic for this inversion. This CTRB1 gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein. provided by RefSeq, Jan 2021
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1).
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"NM_001906" in other vectors (6)
SKU Description Size Price
RC202806 CTRB1 (Myc-DDK-tagged)-Human chymotrypsinogen B1 (CTRB1) 10 ug
$300.00
RC202806L1 Lenti ORF clone of Human chymotrypsinogen B1 (CTRB1), Myc-DDK-tagged 10 ug
$600.00
RC202806L2 Lenti ORF clone of Human chymotrypsinogen B1 (CTRB1), mGFP tagged 10 ug
$600.00
RC202806L3 Lenti ORF clone of Human chymotrypsinogen B1 (CTRB1), Myc-DDK-tagged 10 ug
$600.00
RC202806L4 Lenti ORF clone of Human chymotrypsinogen B1 (CTRB1), mGFP tagged 10 ug
$600.00
RG202806 CTRB1 (tGFP-tagged) - Human chymotrypsinogen B1 (CTRB1) 10 ug
$489.00 $500.00

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