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VDAC3 (NM_005662) Human Untagged Clone

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SKU
SC122051
VDAC3 (untagged)-Human voltage-dependent anion channel 3 (VDAC3), transcript variant 2
  $300.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol VDAC3
Synonyms HD-VDAC3; VDAC-3
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC122051 sequence for NM_005662 edited (data generated by NextGen Sequencing)
ATGTGTAACACACCAACGTACTGTGACCTAGGAAAGGCTGCTAAGGATGTCTTCAACAAA
GGATATGGCTTTGGCATGGTCAAGATAGACCTGAAAACCAAGTCTTGTAGTGGAGTGGAA
TTTTCTACTTCTGGTCATGCTTACACTGATACAGGGAAAGCATCAGGCAACCTAGAAACC
AAATATAAGGTCTGTAACTATGGACTTACCTTCACCCAGAAATGGAACACAGACAATACT
CTAGGGACAGAAATCTCTTGGGAGAATAAGTTGGCTGAAGGGTTGAAACTGACTCTTGAT
ACCATATTTGTACCGAACACAGGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAACGG
GATTGTTTTAGTGTTGGCAGTAATGTTGATATAGATTTTTCTGGACCAACCATCTATGGC
TGGGCTGTGTTGGCCTTCGAAGGGTGGCTTGCTGGCTATCAGATGAGTTTTGACACAGCC
AAATCCAAACTGTCACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCCAGCTG
CACACACATGTGAACGATGGCACTGAATTTGGAGGTTCTATCTACCAGAAGGTGAATGAG
AAGATTGAAACATCCATAAACCTTGCTTGGACAGCTGGGAGTAACAACACCCGTTTTGGC
ATTGCTGCTAAGTACATGCTGGATTGTAGAACTTCTCTCTCTGCTAAAGTAAATAATGCC
AGCCTGATTGGACTGGGTTATACTCAGACCCTTCGACCAGGAGTCAAATTGACTTTATCA
GCTTTAATCGATGGGAAGAACTTCAGTGCAGGAGGTCACAAGGTTGGCTTGGGATTTGAA
CTGGAAGCTTAA

Clone variation with respect to NM_005662.5
5' Read Nucleotide Sequence
>OriGene 5' read for NM_005662 unedited
ATTTTGTACTACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGAGCAGACCA
GGCCCTCGGGGTGGAGGTCTTTGGTTTCATAAGAGCCTGAGAGAGATTTTTCTAAGATAT
GTGTAACACACCAACGTACTGTGACCTAGGAAAGGCTGCTAAGGATGTCTTCAACAAAGG
ATATGGCTTTGGCATGGTCAAGATAGACCTGAAAACCAAGTCTTGTAGTGGAGTGGAATT
TTCTACTTCTGGTCATGCTTACACTGATACAGGGAAAGCATCAGGCAACCTAGAAACCAA
ATATAAGGTCTGTAACTATGGACTTACCTTCACCCAGAAATGGAACACAGACAATACTCT
AGGGACAGAAATCTCTTGGGAGAATAAGTTGGCTGAAGGGTTGAAACTGACTCTTGATAC
CATATTTGTACCGAACACAGGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAACGGGA
TTGTTTTAGTGTTGGCAGTAATGTTGATATAGATTTTTCTGGACCAACCATCTATGGCTG
GGCTGTGTTGGCCTTCGAAGGGTGGCTTGCTGGCTATCAGATGAGTTTTGACACAGCCAA
ATCCAAACTGTCACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCCAGCTGCA
CACACATGTGAACGATGGCACTGAATTTGGGAGGTTCTATCTACCACGAAGGTGAATGAG
AAAGATTGAAACATCCATAAACCTTGCTTGGACGCTTGGGAGTAACACACCCGGTNTTGC
ATTGTTGCTAAGACATGCCTGAATGGAAAACTTTCTTCTCTGCTAAGTAATAATGCACCC
TGATGGACCTGGTTTATCCCACACCTTCGACCAGAGCCAAATGCTTTACAGCTAATCG
3' Read Nucleotide Sequence
>OriGene 3' read for NM_005662 unedited
GAGTTTTTTTTTCGGGTTTTTTTTTTATGTTCCAAATGTGATGGGTTTATTTTATTTTAC
TATGATGCAAAACCAAAGATTCCACTATAGCACAGAGACCAGTATATTACAAGGTCATGA
AAAAATGGTGTGGGACATGCAGGACGTGATGTACAAACTGGTGGGTCAGATCGTCTCCTC
TAACATGACGCTACACTGTCGCTGAGGAACACATTTAATAACACTTCAGAACTGAACTGA
AACGTGGCACAAACATGACAACTTCCAGGCATGCCTTCAAGCATCTCCCTCAGGAGGGAT
TCGCAACCCCTAGACTTCAGTGTGGGGAGGATTACAATTCTTTGGAAGAATAAAAAGTTC
ACACTTTTGAAATTTCACAGAAGAATTTTAAGGCCAAAACATAGTGGGTTCATTTCTCTT
CACTTCCAGGGACAAATCTGATGCTTTCCTCAAACCACATTAAGCTTCCAGTTCAAATCC
CAAGCCAACCTTGTGACCTCCTGCACTGAAGTTCTTTCCATCGATTAAAGCTGATAAAGT
CAATTTGACTCCTGGGTCGAGGTTCTGAGTATAACCCATTCCATCAGGCTGGCATATTAC
TTTACAGAAGAGAAGTCTTCCTTCCACTGTACTTACCACATGCAAAACGGTGTGTTCTCC
ACTGTCAACCAGTTATGAGGTCAACT
Restriction Sites NotI-NotI |
ACCN NM_005662
Insert Size 1500 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_005662.3, NP_005653.3
RefSeq Size 1414 bp
RefSeq ORF 852 bp
Locus ID 7419
UniProt ID Q9Y277
Cytogenetics 8p11.21
Domains Euk_porin
Protein Families Druggable Genome, Ion Channels: Other
Protein Pathways Calcium signaling pathway, Huntington's disease, Parkinson's disease
Summary This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Oct 2011
Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1.
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Documents
Resources
"NM_005662" in other vectors (6)
SKU Description Size Price
RC208906 VDAC3 (Myc-DDK-tagged)-Human voltage-dependent anion channel 3 (VDAC3), transcript variant 2 10 ug
$450.00
RC208906L1 Lenti ORF clone of Human voltage-dependent anion channel 3 (VDAC3), transcript variant 2, Myc-DDK-tagged 10 ug
$750.00
RC208906L2 Lenti ORF clone of Human voltage-dependent anion channel 3 (VDAC3), transcript variant 2, mGFP tagged 10 ug
$750.00
RC208906L3 Lenti ORF clone of Human voltage-dependent anion channel 3 (VDAC3), transcript variant 2, Myc-DDK-tagged 10 ug
$750.00
RC208906L4 Lenti ORF clone of Human voltage-dependent anion channel 3 (VDAC3), transcript variant 2, mGFP tagged 10 ug
$750.00
RG208906 VDAC3 (tGFP-tagged) - Human voltage-dependent anion channel 3 (VDAC3), transcript variant 2 10 ug
$650.00

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