OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

CD42c (GP1BB) (NM_000407) Human Untagged Clone

Be the first to review this product
SKU
SC119912
GP1BB (untagged)-Human glycoprotein Ib (platelet), beta polypeptide (GP1BB)
  $300.00
In Stock*
Bulk Requests & Clone Modifications

Frequently Bought Together (4)

TA308259 Rabbit polyclonal antibody to CD42c (glycoprotein Ib (platelet), beta polypeptide)
100 ul
$665.00
CC100003 DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
5 x 200 ul
$170.00
PRIMER Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
100 pmol
$59.00
TF81001 TurboFectin Transfection Reagent (1 mL in 1 vial)
1 ml in 1 vial
$530.00

Other products for "CD42c or NM_000407"

Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol CD42c
Synonyms BDPLT1; BS; CD42C; GPIBB; GPIbbeta
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC119912 sequence for NM_000407 edited (data generated by NextGen Sequencing)
ATGGGCTCCGGGCCGCGCGGGGCGCTGAGCTTACTGCTCCTGCTGCTGGCCCCGCCGAGC
CGCCCGGCCGCAGGTTGCCCGGCGCCCTGTAGCTGCGCGGGGACGCTCGTGGACTGCGGG
CGCCGCGGGCTGACTTGGGCCTCGCTGCCGACCGCCTTCCCTGTCGACACAACCGAGCTG
GTGCTGACCGGCAACAACCTGACGGCGCTGCCGCCGGGGCTGCTGGACGCGCTGCCCGCG
CTGCGCACCGCACACCTGGGCGCCAACCCCTGGCGCTGCGACTGCCGCCTTGTGCCGCTG
CGCGCCTGGCTGGCCGGCCGCCCCGAGCGTGCGCCCTACCGCGACCTGCGTTGCGTGGCG
CCCCCAGCGCTGCGCGGCCGCCTGCTGCCCTATCTGGCCGAGGACGAGCTGCGCGCCGCT
TGCGCTCCCGGCCCGCTCTGCTGGGGGGCGCTGGCGGCGCAGCTTGCGCTGCTGGGCCTT
GGGCTGCTGCACGCGTTGCTGCTGGTGCTGCTGCTGTGCCGCCTGCGGAGGCTGCGGGCC
CGGGCCCGCGCTCGCGCCGCAGCCCGGCTGTCGCTGACCGACCCGCTGGTGGCCGAGCGA
GCCGGAACCGACGAGTCCTGA

Clone variation with respect to NM_000407.4
5' Read Nucleotide Sequence
>OriGene 5' read for NM_000407 unedited
NAGTTCATTTTTGTAATAGACTCACTATAGGCGGCCGCGAATTCGGCACCAGGGCCTCCC
GATGTTCCCACCCGCATGATCCCTTCCCGCCACACGATGCTCCGTTTTCTTCCGTTGTGA
ATGCCGCGTCCTGTCCTGGTGACAGGAGAACAATGTTGGTGAACGTCGCAGCGGGTGTCC
GAGTGCTCCGTGTGCCCCTGAGAGCGGGTGGGAGCGGAAGCCTGAGCGGCCTGCGGCCTC
CGGCGATAGTGTGCTATCTGCCGCTGCAGCGCGCGTCCGCGCGGCCTCTGGGCTATTTCT
GGCCAGGCCGCAGCACTGTGGTCGGTGCGGGCGTGGCAGGGGCGGGGCGGCCTTATCGCT
CGGCTCTCCCGCCTACGCCTCCCGCTGCAGAGTAAGCCGGGCTGCCGTCTTCTCGCCATG
GGCTCCGGGCCGCGCGGGGCGCTGAGCTTACTGCTCCTGCTGCTGGCCCCGCCGAGCCGC
CCGGCCGCAGGTTGCCCGGCGCCCTGTAGCTGCGCGGGGACGCTCGTGGACTGCGGGCGC
CGCGGGCTGACTTGGGCCTCGCTGCCGACCGCCTTCCCTGTCGACACAACCGAGCTGGTG
CTGACCGGCAACAACCTGACGGCGCTGCCGCCGGGGCTGCTGGACGCGCTGCCCGCGCTG
CGCACCGCACACCTGGGCGCCAACCCCTGGCGCTGCGACTGCCGCCTTGTGCCGCTGCGC
CCCTGGCTGGCCGGCCGCCCCGAGCGTGCGCCCTACCGCACCTGGGTTTGCGTGGCGCCC
CCAGCGCTGCGCGGCCGCCTGCTGCCCTATCTGGGCCCGAGACGAGCTGCGCCGCCGCTT
GCGCNTCCGGCCGCTCTGCTTGGGNGGCGCTTGCGGGCGCAACTTGCGCTGCTGGGCCTT
GGGCTGCTGCACGCGTTGCTT
3' Read Nucleotide Sequence
>OriGene 3' read for NM_000407 unedited
NTTGACTCTGANACCGCGGCCGCATACTAAGATCAAGTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTCCAAATCAGAAGGGTTTATTCACCACCAAAGTTTGGAGAGGGAGACC
CAGCAGGGTCTGGACCGCTATTGGGCCCCATGGTCCTCCCAACCCTGGAAGTGCGGGTTC
GCCTCCCTCGGGGTAGGGGGGGCAGGATTTCTGTCCCACGTGGTCTGGGCCTGCAGGGGG
GGGGGGTCTGAAAAATGGGCAGCGGAGGAGGCGGGGACCGGTCCAGGTTGGCGCGAGGGC
CCCTCGGGCAGGGTCCTGTCAAGTTTGCAGGCCCGTGTTGCCCACCTCCGGTTTTTTCCT
CAGGACCGCCCTCTTGTCTCTCTCCGCTTGTGTTCCCCTCTCCCCCTTTCTTCCCCCCCC
CCCCCCCACTCTTGCTCCCCCTTCCCCCGCCCTTAAATCTGTCCCCGCCCCTCCATTTTT
CCACCCACTCCTCATTGCGCGCACTTCCCCCTTCCCCCTCCCCTCGCTCCTCACCCCCTA
TTAATTTTTCATTGTGTTTCGCATGTTCTGTTCCCCCCCCCCATTTTCTCTTCCACCTTT
TTCCCCCCCCCTTTCTGTTCCCCTTCCCTTCCACGCCCCGTCCTCCCCTTTACCCCCCCT
TCGCCTCCCCCCCCATCCCTCCCTTTTCTTCTCTTTTCTGCCTTGCTTTTTCCTTGTTAT
TGCCTTCCATTACTTAGCTTGTTCGTCCTTCTTCTTTTTCTCCCCTTTTTTCCCTCTCCT
TATATTCTTTTTTTCTTATCACTAATTCTCCCTACCTCCTTTGCTCACTCTCCTTTCTCC
CTCTGTTCCGCCCCTCTCCCCCCCTCTCGTTTTCGTTCTCCTTCCCTCCCATTCCCTGTA
CCACCATGCCTTCTATCCCCAACCTCGCCTTCCCTTCTTCACTTCTCTCCTCCCCATAAC
CCATCTTCCCATTTACTCACTACTT
Restriction Sites NotI-NotI |
ACCN NM_000407
Insert Size 1400 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_000407.3, NP_000398.1
RefSeq Size 955 bp
RefSeq ORF 621 bp
Locus ID 2812
UniProt ID P13224
Cytogenetics 22q11.21
Domains LRR, LRRCT, LRRNT
Protein Families Druggable Genome, Transmembrane
Protein Pathways ECM-receptor interaction, Hematopoietic cell lineage
Summary Platelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain. Mutations in the GPIb beta subunit have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome and giant platelet disorder. The 206 amino acid precursor of GPIb beta is synthesized from a 1.0 kb mRNA expressed in plateletes and megakaryocytes. A 411 amino acid protein arising from a longer, unspliced transcript in endothelial cells has been described; however, the authenticity of this product has been questioned. Yet another less abundant GPIb beta mRNA species of 3.5 kb, expressed in nonhematopoietic tissues such as endothelium, brain and heart, was shown to result from inefficient usage of a non-consensus polyA signal in the neighboring upstream gene (SEPT5, septin 5). In the absence of polyadenylation from its own imperfect site, the SEPT5 gene produces read-through transcripts that use the consensus polyA signal of this gene. provided by RefSeq, Dec 2010
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
"NM_000407" in other vectors (4)
SKU Description Size Price
RC216738 GP1BB (Myc-DDK-tagged)-Human glycoprotein Ib (platelet), beta polypeptide (GP1BB) 10 ug
$289.00 $300.00
RC216738L3 Lenti-ORF clone of GP1BB (Myc-DDK-tagged)-Human glycoprotein Ib (platelet), beta polypeptide (GP1BB) 10 ug
$600.00
RC216738L4 Lenti-ORF clone of GP1BB (mGFP-tagged)-Human glycoprotein Ib (platelet), beta polypeptide (GP1BB) 10 ug
$600.00
RG216738 GP1BB (tGFP-tagged) - Human glycoprotein Ib (platelet), beta polypeptide (GP1BB) 10 ug
$489.00 $500.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products