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C1R (NM_001733) Human Untagged Clone

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SKU
SC119070
C1R (untagged)-Human complement component 1, r subcomponent (C1R)
  $646.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol C1R
Synonyms EDSPD1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC119070 sequence for NM_001733 edited (data generated by NextGen Sequencing)
ATGTGGCTCTTGTACCTCCTGGTGCCGGCCCTGTTCTGCAGGGCAGGAGGCTCCATTCCC
ATCCCTCAGAAGTTATTTGGGGAGGTGACTTCCCCTCTGTTCCCCAAGCCTTACCCCAAC
AACTTTGAAACAACCACTGTGATCACAGTCCCCACGGGATACAGGGTGAAGCTCGTCTTC
CAGCAGTTTGACCTGGAGCCTTCTGAAGGCTGCTTCTATGATTATGTCAAGATCTCTGCT
GATAAGAAAAGCCTGGGGAGGTTCTGTGGGCAACTGGGTTCTCCACTGGGCAACCCCCCG
GGAAAGAAGGAATTTATGTCCCAAGGGAACAAGATGCTGCTGACCTTCCACACAGACTTC
TCCAACGAGGAGAATGGGACCATCATGTTCTACAAGGGCTTCCTGGCCTACTACCAAGCT
GTGGACCTTGATGAATGTGCTTCCCGGAGCAAATCAGGGGAGGAGGATCCCCAGCCCCAG
TGCCAGCACCTGTGTCACAACTACGTTGGAGGCTACTTCTGTTCCTGCCGTCCAGGCTAT
GAGCTTCAGGAAGACAGGCATTCCTGCCAGGCTGAGTGCAGCAGCGAGCTGTACACGGAG
GCATCAGGCTACATCTCCAGCCTGGAGTACCCTCGGTCCTACCCCCCTGACCTGCGCTGC
AACTACAGCATCCGGGTGGAGCGGGGCCTCACCCTGCACCTCAAGTTCCTGGAGCCTTTT
GATATTGATGACCACCAGCAAGTACACTGCCCCTATGACCAGCTACAGATCTATGCCAAC
GGGAAGAACATTGGCGAGTTCTGTGGGAAGCAAAGGCCCCCCGACCTCGACACCAGCAGC
AATGCTGTGGATCTGCTGTTCTTCACAGATGAGTCGGGGGACAGCCGGGGCTGGAAGCTG
CGCTACACCACCGAGATCATCAAGTGCCCCCAGCCCAAGACCCTAGACGAGTTCACCATC
ATCCAGAACCTGCAGCCTCAGTACCAGTTCCGTGACTACTTCATTGCTACCTGCAAGCAA
GGCTACCAGCTCATAGAGGGGAACCAGGTGCTGCATTCCTTCACAGCTGTCTGCCAGGAT
GATGGCACGTGGCATCGTGCCATGCCCAGATGCAAGATCAAGGACTGTGGGCAGCCCCGA
AACCTGCCTAATGGTGACTTCCGTTACACCACCACAATGGGAGTGAACACCTACAAGGCC
CGTATCCAGTACTACTGCCATGAGCCATATTACAAGATGCAGACCAGAGCTGGCAGCAGG
GAGTCTGAGCAAGGGGTGTACACCTGCACAGCACAGGGCATTTGGAAGAATGAACAGAAG
GGAGAGAAGATTCCTCGGTGCTTGCCAGTGTGTGGGAAGCCCGTGAACCCCGTGGAACAG
AGGCAGCGCATCATCGGAGGGCAAAAAGCCAAGATGGGCAACTTCCCCTGGCAGGTGTTC
ACCAACATCCACGGGCGCGGGGGCGGGGCCCTGCTGGGCGACCGCTGGATCCTCACAGCT
GCCCACACCCTGTATCCCAAGGAACACGAAGCGCAAAGCAACGCCTCTTTGGATGTGTTC
CTGGGCCACACAAATGTGGAAGAGCTCATGAAGCTAGGAAATCACCCCATCCGCAGGGTC
AGCGTCCACCCGGACTACCGTCAGGATGAGTCCTACAATTTTGAGGGGGACATCGCCCTG
CTGGAGCTGGAAAATAGTGTCACCCTGGGTCCCAACCTCCTCCCCATCTGCCTCCCTGAC
AACGATACCTTCTACGACCTGGGCTTGATGGGCTATGTCAGTGGCTTCGGGGTCATGGAG
GAGAAGATTGCTCATGACCTCAGGTTTGTCCGTCTGCCCGTAGCTAATCCACAGGCCTGT
GAGAACTGGCTCCGGGGAAAGAATAGGATGGATGTGTTCTCTCAAAACATGTTCTGTGCT
GGACACCCATCTCTAAAGCAGGACGCCTGCCAGGGGGATAGTGGGGGCGTTTTTGCAGTA
AGGGACCCGAACACTGATCGCTGGGTGGCCACGGGCATCGTGTCCTGGGGCATCGGGTGC
AGCAGGGGCTATGGCTTCTACACCAAAGTGCTCAACTACGTGGACTGGATCAAGAAAGAG
ATGGAGGAGGAGGACTGA

Clone variation with respect to NM_001733.4
455 t=>c
5' Read Nucleotide Sequence
>OriGene 5' read for NM_001733 unedited
AATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGAACACGGCCTTGAG
AAATGTGGCTCTTGTACCTCCTGGTGCCGGCCCTGTTCTGCAGGGCAGGAGGCTCCATTC
CCATCCCTCAGAAGTTATTTGGGGAGGTGACTTCCCCTCTGTTCCCCAAGCCTTACCCCA
ACAACTTTGAAACAACCACTGTGATCACAGTCCCCACGGGATACAGGGTGAAGCTCGTCT
TCCAGCAGTTTGACCTGGAGCCTTCTGAAGGCTGCTTCTATGATTATGTCAAGATCTCTG
CTGATAAGAAAAGCCTGGGGAGGTTCTGTGGGCAACTGGGTTCTCCACTGGGCAACCCCC
CGGGAAAGAAGGAATTTATGTCCCAAGGGAACAAGATGCTGCTGACCTTCCACACAGACT
TCTCCAACGAGGAGAATGGGACCATCATGTTCTACAAGGGCTTCCTGGCCTACTACCAAG
CTGTGGACCTTGATGAATGTGCTTCCCGGAGCAAATCAGGGGAGGAGGATCCCCAGCCCC
AGTGCCAGCACCTGTGTCACAACTACGTTGGAGGCTACTTCTGTTCCTGCCGTCCAGGCT
ATGAGCTTCAGGAAGACAGGCATTCCTGCCAGGCTGAGTGCAGCAGCGAGCTGTACACGG
AGGCATCAGGCTACATCTNCAGCCTGGAGTACCCTCGGTCCTACCCCCCTGACCTGCGCT
GCAACTACAGCATCCGGGTGGAGCGGNGCCTCACCCTGCACCTCAAGTTCCTGGAGCCTT
TTGATATGATGACCACCANCAGTACACTGGCCCTATGACCAGCTACAGATCTATGCCAAC
GGGAAGAACATTGGCGAGGTCTGTGGGAAGCAAAAGCGCCCCGACCTCGACACAGCAGAT
3' Read Nucleotide Sequence
>OriGene 3' read for NM_001733 unedited
GCCGCAATTTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTGCACACTGGCATTTCTC
ATAAAACTTTATTTGGAAAAAGTTATATTCAATGACCCAATGGTATCAAAGTGGAAGAGG
AAAGTGACAACTAGAGATTGATAACTATATCCTCTGCAATCCTCAAAAGAAAGAAAGGGG
CCCTTTGGGTTGTTTCAGGTAAAGTACATCAATGGGACTACAGGAAAGAGAATTTCACAC
ACGGTCTTTCTGCATCAGTAATTTTAATAGAGACTCTTAGTGGTTATCAACAACTGGGCA
GTTGTTTTTTGTTTTTTTTTTCCACACTGCTCTCTGGATTCGAACCTAGTGAATTCTGGG
CTCAGTCCTCCTCCTCCATCTCTTTCTTGATCCAGTCCACGTAGTTGAGCACTTTGGTGT
AAAAGCCATAGCCCCTGCTGCACCCGATGCCCCAGGACACGATGCCCGTGGCCACCCAGC
GATCAGTGTTCGGGTCCCTTACTGCAAAAACGCCCCCACTATCCCCCTGGCAGGCGTCCT
GCTTTAGAGATGGGTGTCCAGCACAGAACATGTTTTGAGAGAACACATCCATCCTATTCT
TTCCCCGGAGCCAGTTCTCACAGGCCTGTGGATTAGCTACGGGCAGACGGACAAACCTGA
GGTCATGAGCAATCTTCTCCTTCATGACCCCGAAGCCACTGACATAGCCCATCAAGGCCC
AGTCGTAAAAGGTATCCTTGTCACGGAGGCAAATGGGGAAGAAGGTTGGGACCCCAGGTG
ACACTATTTTTCCAGCTCCAGCAGGGCGATGTCCCCCTCCAAAATTGTAGACTCATCCTG
CACGGAGTCCGGGTGGACCCTGACCCTGCGGAAGGGGGAATTCCTCACTCATGAGCCCTC
TCCATTTGTGTGGCCAAGACCACTTCCAAAGGCGTGCTTTCCGCTCCGTTCCCTGGAAAC
AGGGGGGGCCCTTTTAGAAC
Restriction Sites NotI-NotI |
ACCN NM_001733
Insert Size 2340 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001733.4, NP_001724.3
RefSeq Size 2526 bp
RefSeq ORF 2118 bp
Locus ID 715
UniProt ID P00736
Cytogenetics 12p13.31
Domains CCP, CUB, EGF, EGF_CA, Tryp_SPc
Protein Families Druggable Genome, Protease
Protein Pathways Complement and coagulation cascades, Systemic lupus erythematosus
Summary This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome. provided by RefSeq, Dec 2018
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Documents
Resources
"NM_001733" in other vectors (6)
SKU Description Size Price
RC223007 C1R (Myc-DDK-tagged)-Human complement component 1, r subcomponent (C1R) 10 ug
$646.00
RC223007L1 Lenti ORF clone of Human complement component 1, r subcomponent (C1R), Myc-DDK-tagged 10 ug
$946.00
RC223007L2 Lenti ORF clone of Human complement component 1, r subcomponent (C1R), mGFP tagged 10 ug
$946.00
RC223007L3 Lenti ORF clone of Human complement component 1, r subcomponent (C1R), Myc-DDK-tagged 10 ug
$946.00
RC223007L4 Lenti ORF clone of Human complement component 1, r subcomponent (C1R), mGFP tagged 10 ug
$946.00
RG223007 C1R (tGFP-tagged) - Human complement component 1, r subcomponent (C1R) 10 ug
$789.00 $846.00

file-alt Citations

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