CD48 (NM_001778) Human Untagged Clone

SKU SC119012

CD48 (untagged)-Human CD48 molecule (CD48)

Product Data

• Type: Human Untagged Clone
• Target Symbol: CD48
• Synonyms: BCM1; BLAST; BLAST1; hCD48; mCD48; MEM-102; SLAMF2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001778 edited; GAATTCGGCACGAGGCTGTCTCCTGCGTTGCTGGGAAGTTCTGGAAGGAAGCATGTGCTC; CAGAGGTTGGGATTCGTGTCTGGCTCTGGAATTGCTACTGCTGCCTCTGTCACTCCTGGT; GACCAGCATTCAAGGTCACTTGGTACATATGACCGTGGTCTCCGGCAGCAACGTGACTCT; GAACATCTCTGAGAGCCTGCCTGAGAACTACAAACAACTAACCTGGTTTTATACTTTCGA; CCAGAAGATTGTAGAATGGGATTCCAGAAAATCTAAGTACTTTGAATCCAAATTTAAAGG; CAGGGTCAGACTTGATCCTCAGAGTGGCGCACTGTACATCTCTAAGGTCCAGAAAGAGGA; CAACAGCACCTACATCATGAGGGTGTTGAAAAAGACTGGGAATGAGCAAGAATGGAAGAT; CAAGCTGCAAGTGCTTGACCCTGTACCCAAGCCTGTCATCAAAATTGAGAAGATAGAAGA; CATGGATGACAACTGTTATCTGAAACTGTCATGTGTGATACCTGGCGAGTCTGTAAACTA; CACCTGGTATGGGGACAAAAGGCCCTTCCCAAAGGAGCTCCAGAACAGTGTGCTTGAAAC; CACCCTTATGCCACATAATTACTCCAGGTGTTATACTTGCCAAGTCAGCAATTCTGTGAG; CAGCAAGAATGGCACGGTCTGCCTCAGTCCACCCTGTACCCTGGCCCGGTCCTTTGGAGT; AGAATGGATTGCAAGTTGGCTAGTGGTCACGGTGCCCACCATTCTTGGCCTGTTACTTAC; CTGAGATGAGCTCTTTTAACTCAAGCGAAACTTCAAGGCCAGAAGATCTTGCCTGTTGGT; GATCATGCTCCTCACCAGGACAGAGACTGTATAGGCTGACCAGAAGCATGCTGCTGAATT; ATCAACGAGGATTTTCAAGTTAACTTTTAAATACTGGTTATTATTTAATTTTATATCCCT; TTGTTGTTTTCTAGTACACAGAGATATAGAGATACACATGCTTTTTTCCCACCCAAAATT; GTGACAACATTATGTGAATGTTTTATTATTTTTTAAAATAAACATTTGATATAATTATCA; ATTAACTGAAAAAAAAAAAAAAAAAACTCGAC;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001778 unedited; NTAAGGTTACGATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCTGTC; TCCTGCGTTGCTGGGAAGTTCTGGAAGGAAGCATGTGCTCCAGAGGTTGGGATTCGTGTC; TGGCTCTGGAATTGCTACTGCTGCCTCTGTCACTCCTGGTGACCAGCATTCAAGGTCACT; TGGTACATATGACCGTGGTCTCCGGCAGCAACGTGACTCTGAACATCTCTGAGAGCCTGC; CTGAGAACTACAAACAACTAACCTGGTTTTATACTTTCGACCAGAAGATTGTAGAATGGG; ATTCCAGAAAATCTAAGTACTTTGAATCCAAATTTAAAGGCAGGGTCAGACTTGATCCTC; AGAGTGGCGCACTGTACATCTCTAAGGTCCAGAAAGAGGACAACAGCACCTACATCATGA; GGGTGTTGAAAAAGACTGGGAATGAGCAAGAATGGAAGATCAAGCTGCAAGTGCTTGACC; CTGTACCCAAGCCTGTCATCAAAATTGAGAAGATAGAAGACATGGATGACAACTGTTATC; TGAAACTGTCATGTGTGATACCTGGCGAGTCTGTAAACTACACCTGGTATGGGGACAAAA; GGCCCTTCCCAAAGGAGCTCCAGAACAGTGTGCTTGAAACCACCCTTATGCCACATAATT; ACTCCAGGTGTTATACTTGCCAAGTCAGCAATTCTGTGAGCAGCAAGAATGGCACGGTCT; GCCTCAGTCCACCCTGTACCCTGACACCGTCCTTTGGAGTAGAATGGATTGCAAGTTGGC; TAGTGGTCACGGTGCACACCATTCTTGGGCCTGTACTTACCTGAGATGAGCTCTTTTAAA; CTCAGCGAAACTTCAAGGCCAGNAAGATCTTGCCTGATGGNTGATCATGCTCCTCACCAG; A;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001778 unedited; GCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCAGTTAATTGATAATTATATCAAATG; TTTATTTTAAAAAATAATAAAACATTCACATAATGTTGTCACAATTTTGGGTGGGAAAAA; AGCATGTGTATCTCTATATCTCTGTGTACTAGAAAACAACAAAGGGATATAAAATTAAAT; AATAACCAGTATTTAAAAGTTAACTTGAAAATCCTCGTTGATAATTCAGCAGCATGCTTC; TGGTCAGCCTATACAGTCTCTGTCCTGGTGAGGAGCATGATCACCAACAGGCAAGATCTT; CTGGCCTTGAAGTTTCGCTTGAGTTAAAAGAGCTCATCTCAGGTAAGTAACAGGCCAAGA; ATGGTGGGCACCGTGACCACTAGCCAACTTGCAATCCATTCTACTCCAAAGGACCGGGCC; AGGGTACAGGGTGGACTGAGGCAGACCGTGCCATTCTTGCTGCTCACAGAATTGCTGACT; TGGCAAGTATAACACCTGGAGTAATTATGTGGCATAAGGGTGGTTTCAAGCACACTGTTC; TGGAGCTCCTTTGGGAAGGGCCTTTTGTCCCCATACCAGGTGTAGTTTACAGACTCGCCA; GGTATCACACATGACAGTTTCAGAAACAGTTGTCATCCATGTCTTCTATCTTCTCAATTT; TGATGACAGGCTTGGGTACAGGGTCAAGCACTTGCAGCTTGATCTTCCATTCTTGCTCAT; TCCCAGNCTTTTTCAACACCCTCATGATGTAGGTGCCTGTGGCCTCTTCTGGACCTAGAG; ATGACAGTGCGCACTCTGAGATCAGTCTGACCCTGCTTTAATTTGGATCAAAGACTAGAT; TTCTTGATCCATCTCAATCTCTGTGCAAGTTAAACAGTTAATGTTGTAGTTTCAGCAGCT; TTAGAAAGTAAAGTCCGTGCTGCGGAACACGGATATGCCCAAGACCTGATGTTGTACCGG; AGGACCAGCCCCTT;
• Restriction Sites: NotI-NotI
• ACCN: NM_001778
• Insert Size: 1120 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001778.2, NP_001769.2
• RefSeq Size: 1099 bp
• RefSeq ORF: 732 bp
• Locus ID: 962
• UniProt ID: P09326
• Cytogenetics: 1q23.3
• Domains: IG
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Natural killer cell mediated cytotoxicity
• Summary: This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]; Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter protein (isoform 1).