CSNK2A2 (NM_001896) Human Untagged Clone

SKU SC118969

CSNK2A2 (untagged)-Human casein kinase 2, alpha prime polypeptide (CSNK2A2)

Product Data

• Type: Human Untagged Clone
• Target Symbol: CSNK2A2
• Synonyms: CK2A2; CK2alpha'; CSNK2A1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001896 edited; ATGCCCGGCCCGGCCGCGGGCAGCAGGGCCCGGGTCTACGCCGAGGTGAACAGTCTGAGG; AGCCGCGAGTACTGGGACTACGAGGCTCACGTCCCGAGCTGGGGTAATCAAGATGATTAC; CAACTGGTTCGAAAACTTGGTCGGGGAAAATATAGTGAAGTATTTGAGGCCATTAATATC; ACCAACAATGAGAGAGTGGTTGTAAAAATCCTGAAGCCAGTGAAGAAAAAGAAGATAAAA; CGAGAGGTTAAGATTCTGGAGAACCTTCGTGGTGGAACAAATATCATTAAGCTGATTGAC; ACTGTAAAGGACCCCGTGTCAAAGACACCAGCTTTGGTATTTGAATATATCAATAATACA; GATTTTAAGCAACTCTACCAGATCCTGACAGACTTTGATATCCGGTTTTATATGTATGAA; CTACTTAAAGCTCTGGATTACTGCCACAGCAAGGGAATCATGCACAGGGATGTGAAACCT; CACAATGTCATGATAGATCACCAACAGAAAAAGCTGCGACTGATAGATTGGGGTCTGGCA; GAATTCTATCATCCTGCTCAGGAGTACAATGTTCGTGTAGCCTCAAGGTACTTCAAGGGA; CCAGAGCTCCTCGTGGACTATCAGATGTATGATTATAGCTTGGACATGTGGAGTTTGGGC; TGTATGTTAGCAAGCATGATCTTTCGAAGGGAACCATTCTTCCATGGACAGGACAACTAT; GACCAGCTTGTTCGCATTGCCAAGGTTCTGGGTACAGAAGAACTGTATGGGTATCTGAAG; AAGTATCACATAGACCTAGATCCACACTTCAACGATATCCTGGGACAACATTCACGGAAA; CGCTGGGAAAACTTTATCCATAGTGAGAACAGACACCTTGTCAGCCCTGAGGCCCTAGAT; CTTCTGGACAAACTTCTGCGATACGACCATCAACAGAGACTGACTGCCAAAGAGGCCATG; GAGCACCCATACTTCTACCCTGTGGTGAAGGAGCAGTCCCAGCCTTGTGCAGACAATGCT; GTGCTTTCCAGTGGTCTCACGGCAGCACGATGA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001896 unedited; GGGGGGGCAACTTTTCTTCCTCCCCCNGGGTCAGAATTGTAAACGACTCACTATAGGCGG; CCGCGAATCGGCACCAGCCCGCGCCCCCAGCCCGCCCGCCCCCGCGGGCCCGGCCTGGCG; CGGCCGCCCGCCGCCGCGCTCCTCCTCCTCCTCCTCCAGCGCCCGGCGGCCCGCTGCCTC; CTCCGCCCGACGCCCCGCGTCCCCCGCCGCGCCGCCGCCGCCACCCTCTGCGCCCCGCGC; CGCCCCCCGGTCCCGCCCGCCATGCCCGGCCCGGCCGCGGGCAGCAGGGCCCGGGTCTAC; GCCGAGGTGAACAGTCTGAGGAGCCGCGAGTACTGGGACTACGAGGCTCACGTCCCGAGC; TGGGGTAATCAAGATGATTACCAACTGGTTCGAAAACTTGGTCGGGGAAAATATAGTGAA; GTATTTGAGGCCATTAATATCACCAACAATGAGAGAGTGGTTGTAAAAATCCTGAAGCCA; GTGAAGAAAAAGAAGATAAAACGAGAGGTTAAGATTCTGGAGAACCTTCGTGGTGGAACA; AATATCATTAAGCTGATTGACACTGTAAAGGACCCCGTGTCAAAGACACCAGCTNTGGTA; TTTGAATATATCAATAATACAGATTNTAAGCAACTCTACCAGATCCTGACAGACTNTGAT; ATCCGGNTNTATATGTATGAACTACTTAAAGCTCTGGATTACTGCCACAGCCAGGGAATC; ATGCACAGGGATGTGAAACCTCANCATGTCATGATAGATCACAACAGAAAAGCTGCGACT; GAAGATTGGGGTCTGGCAGAAATCTATCATCCTGCTCCAGAGTACAATGTTCGTGTAGCC; CTCAGGTACCTCAGGGGACAGNAGCTCCTCGTGACTATCAGAAGNATGAATATAGCCTGA; ACTGTGGGAGTTTGGGCTGTATGTTACCAAGCATGATCTTTCGAGGGACCATTNCTNCTG; GCCAGNACACTATGACAGCTGTTCCATTG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001896 unedited; NCCGTCTTACATNACCGCGCCGCAATCTANGATCGGTTTTTTTTTTTTTTTTTTTTCTTT; TAAAACCTTTTATTCAATAATATATACTCTTTAAAATAATAATATGTAACTGGCCGCCAT; GCCACATACTGCGCCCGTCCCCCCACTGTGGAGTCTGTGGTCAGCTAGTTAGCGTGGTTT; GCTGGAAAAACAGGCGGCCACGGGACGAGTTGAGGGGCTCGGGGAGCAACAGTAACCAAC; AACATTCTGCATACCCTTCACATTCCCCATGCTTTCTGGGTCGGGAAGAAGTCAACAGGA; AGCCAAAGGCAAGTGAGCCTTTTACATTCGGAAGTGAGGTTTGATATACGGTGGTGGGCT; GCCCTTCGCTTGGTCTAGTTCGTGCTCGCCAAACCTGCCACCGTTTTGTGTCTGCTCACG; GAACGTGATCTCTCTATACGCGTTAAGACGTTTGATTTGGTTCTTGTTCTGCTTATGGAA; AAGTGGGAGAACCGCAACAGACCCGTCGCTTTCCAGTCTTCATCGTGCTGCCGTGAGACC; ACTGGAAAGCACAGCATTGTCTGCACAAGGCTGGGACTGCTCCTTCACCACAGGGTAGAA; GTATGGGTGCTCCATGGCCTCTTTGGCAGTCAGTCTCTGTTGATGGTCGTATCGCANAAG; TTTGTCCACGATATCTAGGGCCTCAGGGCTGACAAAGTGTCTGTTCTCACTATGGATAAA; AGTTTCCCAGCGTTTTCCGTGAATGTTTGTCCCAAGGATATCGTTGGAAGTGGGGGATCT; AGGTCTATGTGGATACCTCTTCAAATACCCCTACAAGTTCTCTTGTTCCCAGAACCCTTG; GCATTGCCAACCAAGCTGGTCATAGTTGTCCCTGTCCCTGGGAAG;
• Restriction Sites: NotI-NotI
• ACCN: NM_001896
• Insert Size: 1700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001896.2, NP_001887.1
• RefSeq Size: 1674 bp
• RefSeq ORF: 1053 bp
• Locus ID: 1459
• UniProt ID: P19784
• Cytogenetics: 16q21
• Domains: pkinase, S_TKc, TyrKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Adherens junction, Tight junction, Wnt signaling pathway
• Summary: This gene encodes the alpha', or alpha 2, catalytic subunit of the protein kinase enzyme, casein kinase 2 (CK2). Casein kinase 2 is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha', and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11. [provided by RefSeq, Aug 2017]