MPP3 (NM_001932) Human Untagged Clone

SKU SC118952

MPP3 (untagged)-Human membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) (MPP3), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: MPP3
• Synonyms: DLG3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001932, the custom clone sequence may differ by one or more nucleotides; ; ; ATGCCAGTGCTATCGGAGGACTCTGGTTTGCATGAAACCCTGGCCCTGCTGACCTCCCAGCTCAGACCTG; ACTCCAACCACAAGGAGGAGATGGGCTTCCTGAGGGATGTTTTCAGTGAAAAAAGCCTCAGTTACTTAAT; GAAGATTCATGAGAAGCTTCGCTATTATGAAAGGCAAAGTCCAACCCCAGTTCTGCACAGCGCTGTGGCC; CTCGCTGAGGACGTGATGGAGGAGTTGCAGGCCGCCTCCGTGCACAGTGATGAGAGGGAGCTGCTCCAGC; TGCTGTCCACCCCGCACCTGAGGGCTGTGCTCATGGTACATGACACGGTTGCCCAGAAGAATTTTGACCC; CGTTCTCCCGCCTCTGCCTGACAATATCGATGAGGATTTTGATGAGGAATCGGTGAAGATCGTCCGCTTG; GTGAAGAACAAGGAACCCCTGGGTGCCACCATCCGGCGGGACGAGCACTCAGGGGCTGTTGTGGTGGCCA; GGATCATGCGAGGAGGCGCAGCAGACAGGAGCGGCCTGGTCCACGTTGGAGATGAGCTCCGAGAAGTGAA; CGGGATCGCAGTCCTGCACAAGCGGCCCGACGAGATCAGCCAGATTCTGGCCCAGTCCCAGGGATCCATC; ACCCTAAAAATCATCCCAGCCACCCAGGAGGAAGATCGCTTAAAGGAGAGCAAGGTGTTCATGCGCGCCC; TCTTCCACTACAACCCTCGGGAGGACCGGGCCATCCCTTGCCAGGAGGCGGGCCTGCCCTTCCAGCGCAG; GCAGGTCCTGGAGGTGGTGAGCCAGGACGACCCCACGTGGTGGCAGGCCAAGCGAGTCGGGGACACCAAC; CTTCGAGCCGGCCTCATCCCCTCCAAGGGGTTCCAGGAGAGACGACTAAGCTACCGGAGAGCCGCGGGCA; CCCTGCCGAGCCCCCAGAGCCTCAGGAAGCCCCCCTATGATCAGCCTTGTGACAAAGAGACCTGTGACTG; TGAGGGCTACCTCAAAGGGCACTATGTGGCTGGTCTTCGGAGGAGCTTCCGGCTGGGCTGTAGGGAGAGA; CTGGGTGGCTCGCAGGAAGGAAAGATGTCCTCCGGAGCTGAGTCTCCGGAGCTGCTGACTTACGAAGAGG; TGGCCAGGTACCAACACCAGCCCGGAGAGCGGCCCCGCCTGGTGGTTCTGATCGGGTCTCTGGGAGCCCG; ACTGCACGAGCTGAAGCAAAAGGTGGTGGCTGAGAACCCACAGCACTTTGGCGTCGCTGTTCCACATACC; ACCAGGCCCCGAAAGAGCCATGAGAAGGAAGGAGTGGAATATCACTTTGTGTCTAAGCAAGCATTTGAGG; CCGACTTACATCACAACAAGTTCCTGGAACATGGTGAATATAAGGAAAATCTGTATGGAACCAGCCTGGA; GGCCATTCAGGCTGTTATGGCCAAAAACAAAGTTTGTTTGGTGGATGTGGAGCCAGAAGCACTGAAACAA; CTGAGGACCTCAGAATTTAAACCCTATATTATATTTGTAAAGCCTGCAATTCAGGAAAAAAGAAAAACGC; CACCTATGTCCCCAGCTTGTGAGGACACAGCAGCCCCATTTGATGAGCAGCAGCAAGAGATGGCCGCTTC; TGCCGCCTTCATAGACCGGCATTACGGGCACCTGGTAGACGCCGTGCTGGTGAAGGAGGATCTCCAGGGT; GCCTACAGCCAGCTCAAAGTGGTCTTAGAGAAGCTGAGCAAGGACACTCACTGGGTACCTGTTAGTTGGG; TCAGGTAA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001932 unedited; NGCGTTCGCATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCGGCGGC; CCAGGCTCTGGGCACTCGCGCGGCTCCCGTTCGCGNGACACACATCCCGGCGCGACGAGG; TTCCTTCGGAGAGCGAGCGGGAGTCGGTGCTCGGCCTCCTGCGGGGAGCAGCCCGAGGAA; TCTGCAGGGAGAGGTCGGGAGGTGACAACGCCAGCATGCCAGTGCTATCGGAGGACTCTG; GTTTGCATGAAACCCTGGCCCTGCTGACCTCCCAGCTCAGACCTGACTCCAACCACAAGG; AGGAGATGGGCTTCCTGAGGGATGTTTTCAGTGAAAAAAGCCTCAGTTACTTAATGAAGA; TTCATGAGAAGCTTCGCTATTATGAAAGGCAAAGTCCAACCCCAGTTCTGCACAGCGCTG; TGGCCCTCGCTGAGGACGTGATGGAGGAGTTGCAGGCCGCCTCCGTGCACAGTGATGAGA; GGGAGCTGCTCCAGCTGCTGTCCACCCCGCACCTGAAGGCTGTGCTCATGGTACATGACA; CGGTTGCCCAGAAGAATTTTGACCCCGTTCTCCCGCCTCTGCCTGACATATCGATGAAGA; TTTTGATGAGGAATCGGTGAAGATCGTCCGCTTGGTGAAGAAACAAGGAACCCCTGGTGC; CACCATCNCGCGGNACGAGCACTCAGGNGCTGTTGTGGTGGCCAGNATCATGNNCGAGAG; CGCAGCAGACAGAGCGGCCCTGGTCCACGTTGGAAATGAGCTNCGAGAAATGAACGGGGA; TCGCATTCCTGCACAAGCGGGCCCGACGAGATCAGCCAGATTCTGGCCCAGTCCCAGGGA; TCCATTACCCTAAAAATCCTCCCAGCCACCCAGGAGGAAGAATCCTTAAAGGAAACCAAG; TGTTCATGCC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001932 unedited; TATGTACTCGGCCGCATTCTANGATCGAGTTTTTTCTTTTTTTTTTTTTTTTTTTTTTTT; TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCAGGGCCAACTTGCCTGGGATACTTTAAA; AAAAGAAATGGGTTGTTTTCTGATATGCCCCTTTCAAATCATGATCCAAAGAGGGGCAGG; GAAAAACAACAGACAAAAACCAACAACAAATTTTTTTTCCCACTTATACTTTTTTGGAGG; AGGGAATTTGGGGAAAATTTTCTCCCTTTTTGCCCTTGAAATTCCTTGGGGGAAAAATGA; GGGAGTCTGGACTAAATGATTTTCAAGGGCCCGTCCAATTTGGATGTTCTGGGAAAAAGT; TACCTGACCCAACTAAAAGGTACCCAGGGGGGGTCCTTGCTCAACTTTTTTAAAACCACT; TTGAGCTGGGTGGAGGCCCCCTGGAAATCCTCCTTTACCAACACGGGGTTTACCAGGTGC; CCGTAATGCCGGTCTATTAAGGGGGGAAAAGCGGCCATTTTTTGGTGGTGGTCATAAAAA; GGGGCTGGTGTGTCCTCACAAGCTGGGGACATAGGGGGGGTTTTTTTTTTTTCCTGAATT; GCAGGCTTTACAAATATAATATAGGGTTTAAATTCTGAGGCCCTCAATTGTTTCAAGGCT; TTTGGGTCCACATCCACCACAAAAACTTTGTTTTTGGGCCTAACAGCCTGAATGGGCCCC; AGGCTGGTTCCTAAAGATTTTTCCTTAATTCCCATGTTTCACGAATTTTTTGGATGAAGT; CGGCCCAAAGCTTGTTTAAACAAAGGGAATTCCCCCCTCCTTTTAGGGTCTTTGGGCCGG; GGGGGTTTTTAAAAAAAAAAAAAGCTGGCAAAAATTTCCTTCTAACCCGGGGCCGCACGG; GTTAGGCCCCTTTGGAGTTACGGCGGTGGTTT;
• Restriction Sites: NotI-NotI
• ACCN: NM_001932
• Insert Size: 3000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001932.2, NP_001923.2
• RefSeq Size: 3012 bp
• RefSeq ORF: 1758 bp
• Locus ID: 4356
• UniProt ID: Q13368
• Cytogenetics: 17q21.31
• Domains: Guanylate_kin, GuKc, L27, PDZ, SH3
• Protein Families: Druggable Genome
• Summary: This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (1) encodes the shortest isoform (1).