Factor D (CFD) (NM_001928) Human Untagged Clone
$300.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | Factor D |
| Synonyms | ADIPSIN; ADN; DF; PFD |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_001928 |
| Insert Size | 1020 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001928.2, NP_001919.2 |
| RefSeq Size | 1173 bp |
| RefSeq ORF | 762 bp |
| Locus ID | 1675 |
| UniProt ID | P00746 |
| Cytogenetics | 19p13.3 |
| Domains | Tryp_SPc |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades |
| Summary | This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. provided by RefSeq, Nov 2015 Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1). |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001928" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC209272 | CFD (Myc-DDK-tagged)-Human complement factor D (adipsin) (CFD) | 10 ug |
$289.00
$300.00
|
|
| RC209272L3 | Lenti ORF clone of Human complement factor D (adipsin) (CFD), Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC209272L4 | Lenti ORF clone of Human complement factor D (adipsin) (CFD), mGFP tagged | 10 ug |
$600.00
|
|
| RG209272 | CFD (tGFP-tagged) - Human complement factor D (adipsin) (CFD) | 10 ug |
$500.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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