FGF2 (NM_002006) Human Untagged Clone
$450.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | FGF2 |
| Synonyms | BFGF; FGF-2; FGFB; HBGF-2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | Please inquire | |
| ACCN | NM_002006 |
| Insert Size | 867 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_002006.3, NP_001997.4 |
| RefSeq Size | 6803 bp |
| RefSeq ORF | 867 bp |
| Locus ID | 2247 |
| UniProt ID | P09038 |
| Cytogenetics | 4q28.1 |
| Domains | FGF |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton |
| Summary | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. provided by RefSeq, Jul 2008 Transcript Variant: This transcript may encode multiple distinct isoforms through the use of alternative translation start codons (PMID: 17131363). This record represents use of the 5' most non-AUG start codon and encodes the longest (34-kDa) isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_002006" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC217426 | FGF2 (Myc-DDK-tagged)-Human fibroblast growth factor 2 (basic) (FGF2) | 10 ug |
$450.00
|
|
| RC217426L1 | Lenti ORF clone of Human fibroblast growth factor 2 (basic) (FGF2), Myc-DDK-tagged | 10 ug |
$750.00
|
|
| RC217426L2 | Lenti ORF clone of Human fibroblast growth factor 2 (basic) (FGF2), mGFP tagged | 10 ug |
$750.00
|
|
| RC217426L3 | Lenti ORF clone of Human fibroblast growth factor 2 (basic) (FGF2), Myc-DDK-tagged | 10 ug |
$750.00
|
|
| RC217426L4 | Lenti ORF clone of Human fibroblast growth factor 2 (basic) (FGF2), mGFP tagged | 10 ug |
$750.00
|
|
| RG217426 | FGF2 (tGFP-tagged) - Human fibroblast growth factor 2 (basic) (FGF2) | 10 ug |
$650.00
|
|
Citations
Non-viral gene delivery embedded in biomimetically mineralized matrices for bone tissue engineering
Acri, Laird, Jaidev et al
Tissue Eng Part A (2020)
Acri, Laird, Jaidev et al
Tissue Eng Part A (2020)
AI Summary: OriGene contributed pFGF-2 plasmid (No. SC118884) and pBMP-2 plasmid (No. SC119392) to this study, enabling the investigation of growth factor gene delivery for enhanced bone regeneration in biomimetically mineralized matrices.
Snippet: 13031 open read frame [ORF] ref LC337019.1;Addgene, Watertown, MA) and the pFGF-2 and pBMP-2 were purchased from OriGene (Rockville, MD;FGF-2 plasmid No. SC118884 ORF ref NM_002006.3, BMP-2 plasmid No;- plasmid #13031 ORF ref LC337019.1) and the pFGF-2 and pBMP-2 were purchased from OriGene (Rockville, MD, FGF-2 plasmid #SC118884 ORF ref NM_002006.3, BMP-2 plasmid #SC119392 ORF ref NM_001200.1). …
A Multi-Functional Implant Induces Bone Formation in a Diabetic Model
Khorsand, Acri, Do et al
Adv Healthc Mater (2020) 9 (18), e2000770 DOI: 10.1002/adhm.202000770
Khorsand, Acri, Do et al
Adv Healthc Mater (2020) 9 (18), e2000770 DOI: 10.1002/adhm.202000770
Cited by 17
AI Summary: OriGene Technologies supplied the plasmid DNA encoding BMP-2 and FGF-2, which were essential components used for gene delivery to promote bone regeneration in the diabetic rat model described in the study.
Snippet: Abstract Patients with diabetes mellitus (DM) have defective healing of bone fractures. It was previously shown that nonviral gene delivery of plasmid DNA (pDNA) that independently encodes bone mor...;INS from bovine pancreas powder and 1𝛼,25- dihydroxyvitamin D3 (activated VD3) were acquired from Sigma-Aldrich. Branched PEI (molecular weight: 25 kDa) and the GenElute HP endotoxinfree plasmid maxi...
Regeneration of bone using nanoplex delivery of FGF-2 and BMP-2 genes in diaphyseal long bone radial defects in a diabetic rabbit model
Khorsand, Nicholson, Do et al
J Control Release (2017) 248, 53-59 DOI: 10.1016/j.jconrel.2017.01.008
Khorsand, Nicholson, Do et al
J Control Release (2017) 248, 53-59 DOI: 10.1016/j.jconrel.2017.01.008
Showing 1-3 of 3 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
