OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

IRF2 (NM_002199) Human Untagged Clone

Be the first to review this product
SKU
SC118745
IRF2 (untagged)-Human interferon regulatory factor 2 (IRF2)
  $457.00
In Stock*
Bulk Requests & Clone Modifications

Frequently Bought Together (3)

CC100003 DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
5 x 200 ul
$170.00
PRIMER Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
100 pmol
$59.00
TF81001 TurboFectin Transfection Reagent (1 mL in 1 vial)
1 ml in 1 vial
$530.00

Other products for "IRF2 or NM_002199"

Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol IRF2
Synonyms IRF-2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for NM_002199, the custom clone sequence may differ by one or more nucleotides


ATGCCGGTGGAAAGGATGCGCATGCGCCCGTGGCTGGAGGAGCAGATAAACTCCAACACGATCCCGGGGC
TCAAGTGGCTTAACAAGGAAAAGAAGATTTTTCAGATCCCCTGGATGCATGCGGCTAGACATGGGTGGGA
TGTGGAAAAAGATGCACCACTCTTTAGAAACTGGGCAATCCATACAGGAAAGCATCAACCAGGAGTAGAT
AAACCTGATCCCAAAACATGGAAGGCGAATTTCAGATGCGCCATGAATTCCTTGCCTGATATTGAAGAAG
TCAAGGATAAAAGCATAAAGAAAGGAAATAATGCCTTCAGGGTCTACCGAATGCTGCCCCTATCAGAACG
GCCTTCTAAGAAAGGAAAGAAACCAAAGACAGAAAAAGAAGACAAAGTTAAGCACATCAAGCAAGAACCA
GTTGAGTCATCTCTGGGGCTTAGTAATGGAGTAAGTGATCTTTCTCCTGAGTATGCGGTCCTGACTTCAA
CTATAAAAAATGAAGTGGATAGTACGGTGAACATCATAGTTGTAGGACAGTCCCATCTGGACAGCAACAT
TGAGAATCAAGAGATTGTCACCAATCCGCCAGACATTTGCCAAGTTGTAGAGGTGACCACTGAGAGCGAC
GAGCAGCCGGTCAGCATGAGCGAGCTCTACCCTCTGCAGATCTCCCCCGTGTCTTCCTATGCAGAAAGCG
AAACGACTGATAGTGTGCCCAGCGATGAAGAGAGTGCCGAGGGGCGGCCACACTGGCGGAAGAGGAATAT
TGAAGGCAAACAGTACCTCAGCAACATGGGGACTCGAGGCTCCTACCTGCTGCCCGGCATGGCGTCCTTC
GTCACTTCCAACAAACCGGACCTCCAGGTCACCATCAAAGAGGAGAGCAATCCGGTGCCTTACAACAGCT
CCTGGCCCCCTTTTCAAGACCTCCCCCTTTCTTCCTCCATGACCCCAGCATCCAGCAGCAGTCGGCCAGA
CCGGGAGACCCGGGCCAGCGTCATCAAGAAAACATCGGATATCACCCAGGCCCGCGTCAAGAGCTGTTAA

5' Read Nucleotide Sequence
>OriGene 5' read for NM_002199 unedited
ATTTAGAATTTGTAAACGACTTACTATAGGCGGCCGACGAATTCGCACGAGGCTGGACTG
TTCTCAGGCAAGCCGGGGAGTAACTTTTAGTTTTGCTCCTGCGATTATTCAACTGACGGG
CTTTCATTTCCATTTCACACACCCTAGCAACACTTATACCTTGCGGAATTGTATTGGTAG
NCGTGAAAAAAGCACACTGAGAGGGCACCATGCCGGTGGAAAGGATGCGCATGCGCCCGT
GGCTGGAGGAGCAGATAAACTCCAACACGATCCCGGGGCTCAAGTGGCTTAACAAGGAAA
AGAAGATTTTTCAGATCCCCTGGATGCATGCGGCTAGACATGGGTGGGATGTGGAAAAAG
ATGCACCACTCTTTAGAAACTGGGCAATCCATACAGGAAAGCATCAACCAGGAGTAGATA
AACCTGATCCCAAAACATGGAAGGCGAATTTCAGATGCGCCATGAATTCCTTGCCTGATA
TTGAAGAAGTCAAGGATAAAAGCATAAAGAAAGGAAATAATGCCTTCAGGGTCTACCGAA
TGCTGCCCCTATCAGAACGGCCTTCTAAGAAAGGAAAGAAACCAAAGACAGAAAAAGAAG
ACAAAGTTAAGCACATCAAGCAAGAACCAGTTGAGTCATCTCTGGNGCTTAGTAATGGAG
TAAGTGATCTTTCTCCTGAGTATGCGGTCCTGACTTCAACTATAAAAAATGAAGTGGATA
GTACGGTGAACATCATAGTTGTAGGACAGTCCCATCTGGACAGCAACATTGAGAATCAAG
AGATTGTCACCAATCCGCCAGACATTTGCCAAGTTGTAGAGGTGACCACTGAGAGCGACG
AGCAGCCGGTCAGCATGAGCGAGCTCTACCCTCTGCAGATCTCCCCCGTGTCCTTCTATG
CAGAAGCGAACGACTGATAGTG
3' Read Nucleotide Sequence
>OriGene 3' read for NM_002199 unedited
AAAGATTAAACTATGATATTCATATTNGCATTTATTATNCAATNCCACAGGGAAAATCTG
ATTGCTACATGAGCTCATAAAAGCTTTTTTCACCTTTACAAAATTAAAAAAAAAAATGTG
CCACAAGGATGTAATAACAACTGCTGATAAACAAGAAAAGGAATCTTAAAATTATAAATT
TGCTGTAGAAAAGATAAAAAACAATTATATTTTATTTAGAATTTTACCTTGAATAAAATA
TTCCCCTGTATAAAAAATAAAAAAGCTTGCTCTGGTTAGAATTAGAGTATTTTTGTCTTC
AAATCTGGGAATTTGCATAATATTTCCATGATACTTTTTCCTTTGTACCGCGTGGCATTC
AAGCATAGCAGATTAGAAGGATTTTTTTTAAAGCAGTCTGAAAATGGGACATCTGTAGAG
AAATTCATTTCCTTCTTCTCCTCCGGATGTGGAATGGAAGCTTTGAGGGAAGGAAAAGTA
GGAAAAGAGCGGGATGGGATGGGATGGGATGGGATGGGATGGGATAGGAAGAGAGGCTGG
GGAATGGGCAGAGAAGGGGGTGCTGAGTGTGCTGTGAGATAGAGCAAGATCACAAGAGCG
CCTATCTGTTAGTGCTTTAAGATAAGGTGCAGAAGCAGACTGCAATGTCGCTAGTGCTGC
CTATGTACATATTACAAGGAATAAAAATTCCACCTAGTTCACATTATCTCGTCCCGTCTG
AGGCATCCACTTCCACCTTGCTTGCCCTGACCGTAGGCAATGCAGCACCCTCCACTGCCC
TCGTTGGGCCTTGAAACTTCAGTGAGCACCCCCTGGGGGTATCCAACCGGCTTTTAAAAA
CCAAACCCCTATCAAAGGGGCTGGAGCCCTCGGGTCAAAGAGAAACTTCCACTCTTGGAT
CCGGACACACAACACCCACGCCCCCACGGTTAGGGTTCTCTTCCTTACTTTGCTATAATC
CGCGCGCGCCGTCCTTAATATTATTTCTCTCCCCCCCACAAACCTCCACGTGTCTCAACC
CCCTTCGTTCAGTTAAGGCCTCCTTTTCTT
Restriction Sites NotI-NotI |
ACCN NM_002199
Insert Size 2390 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_002199.2, NP_002190.1
RefSeq Size 2223 bp
RefSeq ORF 1050 bp
Locus ID 3660
UniProt ID P14316
Cytogenetics 4q35.1
Domains IRF
Protein Families Druggable Genome, Transcription Factors
Summary IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. provided by RefSeq, Jul 2008
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
"NM_002199" in other vectors (7)
SKU Description Size Price
RC202102 IRF2 (Myc-DDK-tagged)-Human interferon regulatory factor 2 (IRF2) 10 ug
$457.00
RC202102L1 Lenti ORF clone of Human interferon regulatory factor 2 (IRF2), Myc-DDK-tagged 10 ug
$757.00
RC202102L2 Lenti ORF clone of Human interferon regulatory factor 2 (IRF2), mGFP tagged 10 ug
$757.00
RC202102L3 Lenti ORF clone of Human interferon regulatory factor 2 (IRF2), Myc-DDK-tagged 10 ug
$757.00
RC202102L4 Lenti ORF clone of Human interferon regulatory factor 2 (IRF2), mGFP tagged 10 ug
$757.00
RG202102 IRF2 (tGFP-tagged) - Human interferon regulatory factor 2 (IRF2) 10 ug
$489.00 $657.00
SC322374 IRF2 (untagged)-Human interferon regulatory factor 2 (IRF2) 10 ug
$457.00

file-alt Citations

Lupus-associated endogenous retroviral LTR polymorphism and epigenetic imprinting promote HRES-1/Rab4 expression and mTOR activation
Godavarthy, Kelly, Jimah et al
JCI Insight (2019) 5 (1) DOI: 10.1172/jci.insight.134010
Cited by 25
AI Summary: OriGene contributed to this study by providing the IRF2 cDNA clone (Cat. No. SC118745), which was used to investigate the regulatory role of IRF2 in HRES-1/Rab4 expression and its impact on mTOR activation in lupus.
Snippet: digestion. The ORFs were cloned into the EcoRI and SalI sites of the multiple cloning site within pAAV-IRES-hrGFP plasmid. The ORF for IRF2 was purchased from Origene (Cat. No. SC118745, pCMVXL5 containing IRF2 cDNA). After ligation, plasmids were transfected
Immune mediators regulate CFTR expression through a bifunctional airway-selective enhancer
Zhang, Leir, Harris
Mol. Cell. Biol. (2013) 33 (15), 2843-53 DOI: 10.1128/MCB.00003-13
Cited by 1
AI Summary: OriGene’s IRF1 (SC118744) and IRF2 cDNA clones were used in this study to overexpress these transcription factors in airway epithelial cells, enabling the authors to investigate their roles in regulating CFTR gene expression.
Snippet: RNAiMAX (Life Technologies, Grand Island, NY) per the manufacturer's protocol. Cells 130 were harvested 72 hrs after transfection to isolate whole cell lysate and total RNA. 131 cDNA clones of IRF1 (SC118744, OriGene Technologies Rockville, MD), IRF2 132
Dysregulation of interferon regulatory factors impairs the expression of immunostimulatory molecules in hepatitis C virus genotype 1-infected hepatocytes
Larrea, Riezu-Boj, Aldabe et al
Gut (2013)
Cited by 22
AI Summary: In this study, OriGene products including the IRF2 expression plasmid (OriGene, RC210614) and IRF2 siRNA (OriGene, SR300095) were used to manipulate IRF2 levels in Huh7 cells, enabling the authors to demonstrate that IRF2 regulates IL-7 and IL-15Rα expression in the context of hepatitis C virus infection.
Snippet: Menu. Search BMJ Group Search BMJ Group.
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
Guichard, Amaddeo, Imbeaud et al
Nat. Genet. (2012) 44 (6), 694-8 DOI: 10.1038/ng.2256
Cited by 1460
AI Summary: OriGene’s pCMV6-AC-IRF2 plasmid was used to overexpress IRF2 in cell lines, enabling functional analysis of IRF2’s tumor suppressor role in hepatocellular carcinoma.
Snippet: IRF2 overexpression was performed by transfection of cell lines with the pCMV6-AC plasmid containing the IRF2 coding sequence (Origene) with Lipofectamine LTX (Invitrogen). Results were compared to those obtained with empty pCMV6-AC.
Showing 1-4 of 4 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products