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MEK6 (MAP2K6) (NM_002758) Human Untagged Clone

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SKU
SC118432
MAP2K6 (untagged)-Human mitogen-activated protein kinase kinase 6 (MAP2K6)
  $457.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol MEK6
Synonyms MAPKK6; MEK6; MKK6; PRKMK6; SAPKK-3; SAPKK3
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF sequence for NM_002758 edited
ATGTCTCAGTCGAAAGGCAAGAAGCGAAACCCTGGCCTTAAAATTCCAAAAGAAGCATTT
GAACAACCTCAGACCAGTTCCACACCACCTAGAGATTTAGACTCCAAGGCTTGCATTTCT
ATTGGAAATCAGAACTTTGAGGTGAAGGCAGATGACCTGGAGCCTATAATGGAACTGGGA
CGAGGTGCGTACGGGGTGGTGGAGAAGATGCGGCACGTGCCCAGCGGGCAGATCATGGCA
GTGAAGCGGATCCGAGCCACAGTAAATAGCCAGGAACAGAAACGGCTACTGATGGATTTG
GATATTTCCATGAGGACGGTGGACTGTCCATTCACTGTCACCTTTTATGGCGCACTGTTT
CGGGAGGGTGATGTGTGGATCTGCATGGAGCTCATGGATACATCACTAGATAAATTCTAC
AAACAAGTTATTGATAAAGGCCAGACAATTCCAGAGGACATCTTAGGGAAAATAGCAGTT
TCTATTGTAAAAGCATTAGAACATTTACATAGTAAGCTGTCTGTCATTCACAGAGACGTC
AAGCCTTCTAATGTACTCATCAATGCTCTCGGTCAAGTGAAGATGTGCGATTTTGGAATC
AGTGGCTACTTGGTGGACTCTGTTGCTAAAACAATTGATGCAGGTTGCAAACCATACATG
GCCCCTGAAAGAATAAACCCAGAGCTCAACCAGAAGGGATACAGTGTGAAGTCTGACATT
TGGAGTCTGGGCATCACGATGATTGAGTTGGCCATCCTTCGATTTCCCTATGATTCATGG
GGAACTCCATTTCAGCAGCTCAAACAGGTGGTAGAGGAGCCATCGCCACAACTCCCAGCA
GACAAGTTCTCTGCAGAGTTTGTTGACTTTACCTCACAGTGCTTAAAGAAGAATTCCAAA
GAACGGCCTACATACCCAGAGCTAATGCAACATCCATTTTTCACCCTACATGAATCCAAA
GGAACAGATGTGGCATCTTTTGTAAAACTGATTCTTGGAGACTAA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_002758 unedited
GGTTGCACATTTTGTATACGACTCACTCATAGGGCGGCCGCGATTCGGCACGAGGTGTAG
CTGCAGCACAGCCTTCCCTAACGTTGCAACTGGGGNGAAAAATCACTTTCCAGTCTGTTT
TGCAAGGTGTGCATTTCCATCTTGATTCCCTGAAAGTCCATCTGCTGCATCGGTCAAGAG
AAACTCCACTTGCATGAAGATTGCACGCCTGCAGCTTGCATCTTTGTTGCAAAACTAGCT
ACAGAAGAGAAGCAAGGCAAAGTCTTTTGTGCTCCCCTCCCCCATCAAAGGAAAGGGGAA
AATGTCTCAGTCGAAAGGCAAGAAGCGAAACCCTGGCCTTAAAATTCCAAAAGAAGCATT
TGAACAACCTCAGACCAGTTCCACACCACCTAGAGATTTAGACTCCAAGGCTTGCATTTC
TATTGGAAATCAGAACTTTGAGGTGAAGGCAGATGACCTGGAGCCTATAATGGAACTGGG
ACGAGGTGCGTACGGGGTGGTGGAGAAGATGCGGCACGTGCCCAGCGGGCAGATCATGGC
AGTGAAGCGGATCCGAGCCACAGTAAATAGCCAGGAACAGAAACGGCTACTGATGGATTT
GGATATTTCCATGAGGACGGTGGACTGTCCATTCACTGTCACCTTTTATGGCGCACTGTT
TCGGGAGGGTGATGTGTGGATCTGCATGGAGCTCATGGATACATCACTAGATAAATTCTA
CAAACAAGTTATTGATAAAGGCCACGACATTCCAGAGGACATCTTAGGNAAAAATAGCAG
TTCTATTGTAAAAGCATTAGAACATTTACATAGTAAGCTGTCTGTCATTCACAGAGACGT
CAAGCCTTCTTATGTACTCATCAATGCTCTCCGGTCAGTGAAGATGTGCGATTNTGGAAT
CAGTGGCTCCTTGTGGGACCTGTTGCTAAAC
Restriction Sites NotI-NotI |
ACCN NM_002758
Insert Size 1850 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_002758.2, NP_002749.2
RefSeq Size 2924 bp
RefSeq ORF 1005 bp
Locus ID 5608
UniProt ID P52564
Cytogenetics 17q24.3
Domains pkinase, S_TKc, TyrKc
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Amyotrophic lateral sclerosis (ALS), Fc epsilon RI signaling pathway, GnRH signaling pathway, MAPK signaling pathway, Toll-like receptor signaling pathway
Summary This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. provided by RefSeq, Jul 2008
Transcript Variant: This variant (1) differs from variant 2 in its 5' terminus which contains an upstream in-frame translational start codon. Thus, this variant encodes isoform 1 that is 56 aa longer at N-terminus than isoform 2.
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Documents
Resources
"NM_002758" in other vectors (6)
SKU Description Size Price
RC204481 MAP2K6 (Myc-DDK-tagged)-Human mitogen-activated protein kinase kinase 6 (MAP2K6) 10 ug
$457.00
RC204481L1 Lenti ORF clone of Human mitogen-activated protein kinase kinase 6 (MAP2K6), Myc-DDK-tagged 10 ug
$757.00
RC204481L2 Lenti ORF clone of Human mitogen-activated protein kinase kinase 6 (MAP2K6), mGFP tagged 10 ug
$757.00
RC204481L3 Lenti ORF clone of Human mitogen-activated protein kinase kinase 6 (MAP2K6), Myc-DDK-tagged 10 ug
$757.00
RC204481L4 Lenti ORF clone of Human mitogen-activated protein kinase kinase 6 (MAP2K6), mGFP tagged 10 ug
$757.00
RG204481 MAP2K6 (tGFP-tagged) - Human mitogen-activated protein kinase kinase 6 (MAP2K6) 10 ug
$489.00 $657.00

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