MEK6 (MAP2K6) Rabbit Polyclonal Antibody

SKU TA321524

Anti-MAP2K6 Rabbit Polyclonal Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: Mouse muscle tissue; IHC: 25-100; Positive control: Human liver cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 31-297 amino acids of human mitogen-activated protein kinase kinase 6
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 37 kDa
• Gene Name: mitogen-activated protein kinase kinase 6
• Database Link:
  NP_002749
  P52564
• Background: This gene encodes a member of the dual specificity protein kinase family; which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases; also known as extracellular signal-regulated kinases (ERKs); act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway; this gene is involved in many cellular processes such as stress induced cell cycle arrest; transcription activation and apoptosis.
• Synonyms: MAPKK6; MEK6; MKK6; PRKMK6; SAPKK-3; SAPKK3

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Fc epsilon RI signaling pathway, GnRH signaling pathway, MAPK signaling pathway, Toll-like receptor signaling pathway