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TSPAN6 (NM_003270) Human Untagged Clone

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SKU
SC118090
TSPAN6 (untagged)-Human tetraspanin 6 (TSPAN6)
  $300.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol TSPAN6
Synonyms T245; TM4SF6; TSPAN-6
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC118090 sequence for NM_003270 edited (data generated by NextGen Sequencing)
ATGGCGTCCCCGTCTCGGAGACTGCAGACTAAACCAGTCATTACTTGTTTCAAGAGCGTT
CTGCTAATCTACACTTTTATTTTCTGGATCACTGGCGTTATCCTTCTTGCAGTTGGCATT
TGGGGCAAGGTGAGCCTGGAGAATTACTTTTCTCTTTTAAATGAGAAGGCCACCAATGTC
CCCTTCGTGCTCATTGCTACTGGTACCGTCATTATTCTTTTGGGCACCTTTGGTTGTTTT
GCTACCTGCCGAGCTTCTGCATGGATGCTAAAACTGTATGCAATGTTTCTGACTCTCGTT
TTTTTGGTCGAACTGGTCGCTGCCATCGTAGGATTTGTTTTCAGACATGAGATTAAGAAC
AGCTTTAAGAATAATTATGAGAAGGCTTTGAAGCAGTATAACTCTACAGGAGATTATAGA
AGCCATGCAGTAGACAAGATCCAAAATACGTTGCATTGTTGTGGTGTCACCGATTATAGA
GATTGGACAGATACTAATTATTACTCAGAAAAAGGATTTCCTAAGAGTTGCTGTAAACTT
GAAGATTGTACTCCACAGAGAGATGCAGACAAAGTAAACAATGAAGGTTGTTTTATAAAG
GTGATGACCATTATAGAGTCAGAAATGGGAGTCGTTGCAGGAATTTCCTTTGGAGTTGCT
TGCTTCCAACTGATTGGAATCTTTCTCGCCTACTGCCTCTCTCGTGCCATAACAAATAAC
CAGTATGAGATAGTGTAA

Clone variation with respect to NM_003270.2
5' Read Nucleotide Sequence
>OriGene 5' read for NM_003270 unedited
AATTTTCGGATTTGTAAACACGACTTCACTATAGGGCGGACCGCCAATTCGGCACGAGGG
CAGGGTCTCGGGCTAGTCATGGCGTCCCCGTCTCGGAGACTGCAGACTAAACCAGTCATT
ACTTGTTTCAAGAGCGTTCTGCTAATCTACACTTTTATTTTCTGGATCACTGGCGTTATC
CTTCTTGCAGTTGGCATTTGGGGCAAGGTGAGCCTGGAGAATTACTTTTCTCTTTTAAAT
GAGAAGGCCACCAATGTCCCCTTCGTGCTCATTGCTACTGGTACCGTCATTATTCTTTTG
GGCACCTTTGGTTGTTTTGCTACCTGCCGAGCTTCTGCATGGATGCTAAAACTGTATGCA
ATGTTTCTGACTCTCGTTTTTTTGGTCGAACTGGTCGCTGCCATCGTAGGATTTGTTTTC
AGACATGAGATTAAGAACAGCTTTAAGAATAATTATGAGAAGGCTTTGAAGCAGTATAAC
TCTACAGGAGATTATAGAAGCCATGCAGTAGACAAGATCCAAAATACGTTGCATTGTTGT
GGTGTCACCGATTATAGAGATTGGACAGATACTAATTATTACTCAGAAAAAGGATTTCCT
AAGAGTTGCTGTAAACTTGAAGATTGTACTCCACAGAGAGATGCAGACAAAGTAAACAAT
GAAGGTTGTTTTATAAAGGTGATGACCATTATAGAGTCAGAAATGGGAGTCGTTGCAGGA
ATTTCCTTTGGAGTTGCTTGCTTCCAACTGATTGGAATCTTTCTCGCCTACTGCCTCTCT
CGTGCCATAACANATAACCAGTATGAGATAGTGTAACCCAATGTATCTGTGGGCCTATTC
CTCTCTACCTTTAAGGACATTTAGGGTCCCCCCTGTGAATTAAAAAAGTGCTTGNCTGNA
GAACTGACACACTACTTACTGATAN
3' Read Nucleotide Sequence
>OriGene 3' read for NM_003270 unedited
CGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTACTTCATTTACAATTTACTAACTCTTCCAGTGTTTCAAAGGGATACA
GGGTTTCAACGATCTAACATGAATGGGATAAAAGGGGGACTTAAAACATAGCAAACATAC
CTTTTGATTGAATCACCCCACTGCGAGCACGGATCTTGATTGAATCACCCTATTGGGGTA
GTTTTAGGGCTACATACATCTTGATTGAATCAACCTACTGGGGTAGTTTTTTGGGCTATC
AAAAAGTAGGGTTGGCAGTTCTCCACCCAAGCAACTTTTTAATTCACAGGGGGGACCCTA
AATGTCCTTAAAGGGAAAGAGGAATAGGCCCACAAATACATTGGGTTACACTATCTCATA
CTGGTTATTTGTTATGGCACCAAAGAGGCAGTAGGCGAAAAAAATTCCAATCAGTTGGAA
GCAAGCAACTCCAAAGGAAATTCCTGCAACGACTCCCATTTCTGACTCTATAATGGGCAT
CACCTTTATAAAACAACCTTCATTGGTTACTTTGCCTGCATCCCTCTGGGGAGAACAATC
TTCAAGTTTACAACAACTCTTAAGAAATCCTTTTTCTGAGAATAATTAGAATCTGCCCCA
TCTCTATAATCGGGGACACCCCAACCATGCAACCGTATTTGGAATCTCTGCCTACTGGCT
GGGCTTCTATAAACCTCCTGGAAAGGTATACTGCCTCAAAACCCTTCTCCATATTAATTT
TTAAAGCTGGTCTTAAATCCCATGTCTGGAAACCAAATCTTCGATGGCGGCGACCCTTTC
GCCAAAAAAACCAGAGTCAAAACCTTTGCCTACCGTTTTAGCCTCCCGGCCAAACCTCGG
GGGGACCAAACCACCCAGGGGGCCCAAGAATAATGCCGGTCCCTTCCATGAGCCCAAGGG
GC
Restriction Sites ECoRI-NOT |
ACCN NM_003270
Insert Size 1220 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_003270.2, NP_003261.1
RefSeq Size 2069 bp
RefSeq ORF 738 bp
Locus ID 7105
UniProt ID O43657
Cytogenetics Xq22.1
Domains transmembrane4
Protein Families Transmembrane
Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. provided by RefSeq, Jul 2013
Transcript Variant: This variant (1) encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
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Documents
Resources
"NM_003270" in other vectors (7)
SKU Description Size Price
RC202014 TSPAN6 (Myc-DDK-tagged)-Human tetraspanin 6 (TSPAN6) 10 ug
$300.00
RC202014L1 Lenti ORF clone of Human tetraspanin 6 (TSPAN6), Myc-DDK-tagged 10 ug
$600.00
RC202014L2 Lenti ORF clone of Human tetraspanin 6 (TSPAN6), mGFP tagged 10 ug
$600.00
RC202014L3 Lenti ORF clone of Human tetraspanin 6 (TSPAN6), Myc-DDK-tagged 10 ug
$600.00
RC202014L4 Lenti ORF clone of Human tetraspanin 6 (TSPAN6), mGFP tagged 10 ug
$600.00
RG202014 TSPAN6 (tGFP-tagged) - Human tetraspanin 6 (TSPAN6) 10 ug
$500.00
SC323749 TSPAN6 (untagged)-Human tetraspanin 6 (TSPAN6) 10 ug
$300.00

file-alt Citations

Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus
Bonaparte, Dimitrov, Bossart et al
Proc Natl Acad Sci U S A (2005) 102 (30), 10652-7 DOI: 10.1073/pnas.0504887102
Cited by 488
AI Summary: OriGene contributed to this study by providing expression vectors (OriGene TrueClone cDNA clones) for the top candidate genes, enabling the identification of human ephrin-B2 (EFNB2) as a functional receptor for Hendra and Nipah viruses.
Showing 1-1 of 1 papers.
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