RAB7 (RAB7A) (NM_004637) Human Untagged Clone

CAT#: SC117240

RAB7A (untagged)-Human RAB7A, member RAS oncogene family (RAB7A)


  "NM_004637" in other vectors (6)

Reconstitution Protocol

USD 450.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol RAB7
Synonyms CMT2B; PRO2706; RAB7
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC117240 sequence for NM_004637 edited (data generated by NextGen Sequencing)
ATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGG
AAGACATCACTCATGAACCAGTATGTGAATAAGAAATTCAGCAATCAGTACAAAGCCACA
ATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAG
ATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGT
GCAGACTGCTGCGTTCTGGTATTTGATGTGACTGCCCCCAACACATTCAAAACCCTAGAT
AGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAACTTCCCATTT
GTTGTGTTGGGAAACAAGATTGACCTCGAAAACAGACAAGTGGCCACAAAGCGGGCACAG
GCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAGGCCATC
AACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACTTAAGCAGGAAACGGAGGTG
GAGCTGTACAACGAATTTCCTGAACCTATCAAACTGGACAAGAATGACCGGGCCAAGGCC
TCGGCAGAAAGCTGCAGTTGCTGA

Clone variation with respect to NM_004637.5
>OriGene 5' read for NM_004637 unedited
TGTATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCC
GAATTCGGCACGAGGATAAAGCCTGAGGCGGCGGCAGCGGCGGAGTTGGCGGCTTGGAGA
GCTCGGGAGAGTTCCCTGGAACCAGAACTTGGACCTTCTCGCTTCTGTCCTCCGTTTAGT
CTCCTCCTCGGCGGGAGCCCTCGCGACGCGCCCGGCCCGGAGCCCCCAGCGCAGCGGCCG
CGTTTGAAGGATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTC
TGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAATAAGAAATTCAGCAATCAGTA
CAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGT
CACAATGCAGATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTT
CTACAGAGGTGCAGACTGCTGCGTTCTGGTATTTGATGTGACTGCCCCCAACACATTCAA
AACCCTAGATAGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAA
CTTCCCATTTGTTGTGTCTGGGAAACAAGATCGACCCTCGAAACCAGACAGTGGCCACAA
AAGCGGCACAGGCCTGTTGCTACAGCAAAAACCACATTCCCTACTTTGAGACCAGTGCCA
CAGAAGCCATCCACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACCTTAGCATG
AAACGGAGGTGGAGCTGTACACCGAATTTCCTGACCTATCAACTGGACAAGAATGCCCGG
GCCAAGGCTCNGCANAAAGCTGCACTTGCTGAGGGGCCTTGAGAGTTGACCCAGATCCTT
TCAAACCAGGACCACGTAAGCGCTCAACCAATTCCCTT
>OriGene 3' read for NM_004637 unedited
TGACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTAACAAGGGTCTTGGTCAATTTTATTGGCATTGGG
TTCATTTTTTTACAAAAAAACTCACCCCACCCCCTAAAATGTAAACCTTTGGAAAAAGGA
AAAGTGCTCCGTTAAACAAGCTACAATGCAGGGGCGAAATTCTCTAGGAAGGGAGCAAAA
CTGCCAGGGTTCCAACCAAAGAAAGAGGTTAATTAATAATGGGCAATATTGGGGAAATGG
GTGGGGAAAANAGAAAAAGCTCCGCTAACCTAAGAAACCACAACCCTGAAAGGAGCGCCT
TCTAGAACAAAGGTAAAATCACTAGGACAGATCTGTTAAGGTTTTCCTTTCACTCTTGTA
NAAAATGCTGATCTAACGGGAGTTTTGAGTGTGGGGCAGGGGGGAAAAAAAAGAAAGAAA
TGAGAATTTAATTTTTGAAATACGGGATTTATCCATCGACATACCACTGTATATGCAAAT
CACGTTTTGGAAAATTANACACGGAAGGGACCTGACGTTTTCCCCTGAAAAATGAAAAGC
TTTTTGCTCTTAGTCTTTGATAAAGGCGACATAATCTTGGGTTACTGACAGAATACTGCC
GCTACCGGGATTTCCAATCTGAGTACACCTTGAATCCAACAGGGTTAACCCTCCCCTTAA
GGGCTGTTTTCAGGACTAAAACCTTATCAAGAATTTTTACCTAATTAACATTTTATTGGG
GCTTTTTTGCATGTCCTAAAAACTTTTCTAAAAACTTCCTTATAAAGGGTCTGAAAAAGA
CTTGTTTTTAAAGTACACCCTTACGATGATCTCCAAATCNCCTGAAAATGGGGTAACCTT
ATGGGCTGGGCCCACACTCCAGGGGTCCCTTAGGGGGGGGAAGGGGGGANACACCCNGAC
TTAAAATCCGTTTA
Restriction Sites NotI-NotI     
ACCN NM_004637
Insert Size 2100 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_004637.5, NP_004628.4
RefSeq Size 2240 bp
RefSeq ORF 624 bp
Locus ID 7879
UniProt ID P51149
Cytogenetics 3q21.3
Protein Families Druggable Genome
Gene Summary RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]

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