OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

VAPB (NM_004738) Human Untagged Clone

Be the first to review this product
SKU
SC117187
VAPB (untagged)-Human VAMP (vesicle-associated membrane protein)-associated protein B and C (VAPB), transcript variant 1
  $300.00
In Stock*
Bulk Requests & Clone Modifications

Frequently Bought Together (4)

TA808674 VAPB mouse monoclonal antibody, clone OTI4D8 (formerly 4D8) 100 ul
$447.00
CC100003 DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
5 x 200 ul
$170.00
PRIMER Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
100 pmol
$59.00
TF81001 TurboFectin Transfection Reagent (1 mL in 1 vial)
1 ml in 1 vial
$530.00

Other products for "VAPB or NM_004738"

Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol VAPB
Synonyms ALS8; VAMP-B; VAP-B
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for NM_004738, the custom clone sequence may differ by one or more nucleotides


ATGGCGAAGGTGGAGCAGGTCCTGAGCCTCGAGCCGCAGCACGAGCTCAAATTCCGAGGTCCCTTCACCG
ATGTTGTCACCACCAACCTAAAGCTTGGCAACCCGACAGACCGAAATGTGTGTTTTAAGGTGAAGACTAC
AGCACCACGTAGGTACTGTGTGAGGCCCAACAGCGGAATCATCGATGCAGGGGCCTCAATTAATGTATCT
GTGATGTTACAGCCTTTCGATTATGATCCCAATGAGAAAAGTAAACACAAGTTTATGGTTCAGTCTATGT
TTGCTCCAACTGACACTTCAGATATGGAAGCAGTATGGAAGGAGGCAAAACCGGAAGACCTTATGGATTC
AAAACTTAGATGTGTGTTTGAATTGCCAGCAGAGAATGATAAACCACATGATGTAGAAATAAATAAAATT
ATATCCACAACTGCATCAAAGACAGAAACACCAATAGTGTCTAAGTCTCTGAGTTCTTCTTTGGATGACA
CCGAAGTTAAGAAGGTTATGGAAGAATGTAAGAGGCTGCAAGGTGAAGTTCAGAGGCTACGGGAGGAGAA
CAAGCAGTTCAAGGAAGAAGATGGACTGCGGATGAGGAAGACAGTGCAGAGCAACAGCCCCATTTCAGCA
TTAGCCCCAACTGGGAAGGAAGAAGGCCTTAGCACCCGGCTCTTGGCTCTGGTGGTTTTGTTCTTTATCG
TTGGTGTAATTATTGGGAAGATTGCCTTGTAG

5' Read Nucleotide Sequence
>OriGene 5' read for NM_004738 unedited
GCTTTGCGGATTTGTAATCCGACTTACTATAGGGNCGGCACGCGCAATTCGGCACGAGGC
GCCCTCGCCCTCCGCCCCTGCGCCTGCACCGCGTAGACCGACCCCCCCCCCCATCGCGCC
CACCCGGTAGAGGACCCCCGCCCGTGCCCCGACCGGTCCCCGCCTTTTTGTAAAACTTAA
AGCGGGCGCAGCATTAACGCTTCCCGCCCCGGTGACCTCTCATGGGTCTCCCCGCCAAAG
GTGCTCCGCCGCTAAGGAACATGGCGAAGGTGGAGCAGGTCCTGAGCCTCGAGCCGCAGC
ACGAGCTCAAATTCCGAGGTCCCTTCACCGATGTTGTCACCACCAACCTAAAGCTTGGCA
ACCCGACAGACCGAAATGTGTGTTTTAAGGTGAAGACTACAGCACCACGTAGGTACTGTG
TGAGGCCCAACAGCGGAATCATCGATGCAGGGGCCTCAATTAATGTATCTGTGATGTTAC
AGCCTTTCGATTATGATCCCAATGAGAAAAGTAAACACAAGTTTATGGTTCAGTCTATGT
TTGCTCCAACTGACACTTCAGATATGGAAGCAGTATGGAAGGAGGCAAAACCGGAAGACC
TTATGGATTCAAAACTTAGATGTGTGTTTGAATTGCCAGCAGAGAATGATAAACCACATG
ATGTAGAAATAAATAAAATTATATCCACAACTGCATCANAGACAGANACACCAATAGTGT
CTAAGTCTCTGAGTTCTTCTTTGGATGACACCGAAAGTAAGAAAGTTATGGAAGAATGCT
AGATGCTGNCAGGTGAGCTCANATGCTACGGGAGGAGAACAAGCAGTTCAAGGAAAGAGA
TGGACTGCNGATGATGAAGACAGTGCAGAGCATCAGCCCCATTGCAGCATTAGCCCCCAC
TGGGAAGGAAGAATGCCNNTANCACCCNGCTCTTGGCTCTGGTAGGGTTGGTCCTTATCG
TAGGAGTATNTATG
3' Read Nucleotide Sequence
>OriGene 3' read for NM_004738 unedited
TTTATTATAATTTTTCTTTTCAGAATGCTACATAGTCAAACAGAACTGGGTTGGTCTTTT
ATGGCATAAAATTAATTCACAGTCAAACTCTCAACTAGTACTAGAAGGATTCGCTGAAGA
GTTTCTCTCTTCCCTTGCTCCCCACCCACAACTGCTGGTGCCCTCGCTTCTAACCCTCTG
CAGCCCGATCCATTTGTCCTGACTCCAGGCTAGGTCCCCAAGGGGAGGTCAGGCTCAGAC
TTGGACCTGGGCGCTGGAAGTGTGAGTAATGGTTGAGAGGTGGTATAAGAACAATCTAGA
AGACTGACTACTCTTCATTAAAAAAGGTAACCTAGAGTTGACTGTCACTACTGAGAATTT
CCCTCCCTATGACAGTTGTTATTTACTGACCCAGAAAAAACACTTCCTGGCAGCTCTTCT
CCAGCATCCCAATAAACCCCACCTCCACATGACCAGACTCTCCAGAGACAGAGGAGCCCA
CAGCCCTCCAGCAGCAATACCAGTTCACCCAACAGAGTTCAGCAGCACGCAGCATTAACT
GTACTCTTGTGACAATAAGAAAACATGAGATGAAATACATTAAATAAGTTAAATATGCAT
TAAACATCTCTGAATAACAGTTTGACTTCACTACATGAACCAATACAAATTTAGCTTGGT
CCCTTTAAGTGAACAAAGCACTGCCATNTATTTCCAAAGCGCTGGGTCAATCAGTCAACA
CACGCCTCTCACTTATGACGAGTACGTCTGATGCTGNCACAGTGCAATTCCTTTTGGCTT
CTGACTCTGNTCATCAGTCCCAAGGAGCTGATGGCTTGGACAGAAACTGAGACAGGNAAA
GCAGNCTGGCCCGGNAGTGGGCCACGTNNGGGACTACTGTGTGNAGCTGACCGNNACTCC
CACATGCTGGGNCTCAGCTCCCCAGGGCCAGCACCACAGGCGAGGAGGGTTTCATTNTAG
AGAGGTATCCAGCTCTGTACCAGGCCTACATGNTAAATGACNTACATTTGCATGNGGCAT
ACTAAGGGTTCCCCTGCATATAAGACTA
Restriction Sites NotI-NotI |
ACCN NM_004738
Insert Size 2440 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_004738.3, NP_004729.1
RefSeq Size 3689 bp
RefSeq ORF 732 bp
Locus ID 9217
UniProt ID O95292
Cytogenetics 20q13.32
Domains MSP_domain
Protein Families Transmembrane
Summary The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking. provided by RefSeq, Jul 2008
Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
"NM_004738" in other vectors (6)
SKU Description Size Price
RC200517 VAPB (Myc-DDK-tagged)-Human VAMP (vesicle-associated membrane protein)-associated protein B and C (VAPB), transcript variant 1 10 ug
$450.00
RC200517L1 Lenti ORF clone of Human VAMP (vesicle-associated membrane protein)-associated protein B and C (VAPB), transcript variant 1, Myc-DDK-tagged 10 ug
$750.00
RC200517L2 Lenti ORF clone of Human VAMP (vesicle-associated membrane protein)-associated protein B and C (VAPB), transcript variant 1, mGFP tagged 10 ug
$750.00
RC200517L3 Lenti ORF clone of Human VAMP (vesicle-associated membrane protein)-associated protein B and C (VAPB), transcript variant 1, Myc-DDK-tagged 10 ug
$750.00
RC200517L4 Lenti ORF clone of Human VAMP (vesicle-associated membrane protein)-associated protein B and C (VAPB), transcript variant 1, mGFP tagged 10 ug
$750.00
RG200517 VAPB (tGFP-tagged) - Human VAMP (vesicle-associated membrane protein)-associated protein B and C (VAPB), transcript variant 1 10 ug
$650.00

file-alt Citations

Amyotrophic lateral sclerosis-related VAPB P56S mutation differentially affects the function and survival of corticospinal and spinal motor neurons
Aliaga, Lai, Yu et al
Hum. Mol. Genet. (2013)
Cited by 72
AI Summary: OriGene's QuikChange Site-Directed Mutagenesis Kit was used to generate the VAPB P56S mutation, enabling the study of its effects on motor neuron function and survival in the ALS8 mouse model.
Snippet: first detected at 2 months of age, and this gait abnormality was persistent without significant deterioration through their life span (Fig. 2E-F). In contrast, no significant ... (OriGene Technologies Inc, Rockville, MD) using the QuikChange Site-Directed
VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis
De Vos, Mórotz, Stoica et al
Hum. Mol. Genet. (2012) 21 (6), 1299-311 DOI: 10.1093/hmg/ddr559
Cited by 591
AI Summary: In this study, OriGene products including the VAPB expression plasmid (RC213751) and VAPB shRNA (TF313693) were used to manipulate VAPB levels in cells, enabling the authors to investigate VAPB’s interaction with PTPIP51 and its role in regulating calcium homeostasis between the endoplasmic reticulum and mitochondria.
Snippet: We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. Find out more Skip Navigation.
FigureFigureFigure
Showing 1-2 of 2 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products