CTNS (NM_004937) Human Untagged Clone
$457.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | CTNS |
| Synonyms | CTNS-LSB; PQLC4; SLC66A4 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_004937 |
| Insert Size | 2550 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_004937.1, NP_004928.1 |
| RefSeq Size | 2611 bp |
| RefSeq ORF | 1104 bp |
| Locus ID | 1497 |
| UniProt ID | O60931 |
| Cytogenetics | 17p13.2 |
| Domains | CTNS |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Lysosome |
| Summary | This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2009 Transcript Variant: This variant (2) differs in the 5' UTR, 3' UTR and 3' coding region, compared to variant 1, resulting in an isoform (2) with a distinct and shorter C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
"NM_004937" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC213151 | CTNS (Myc-DDK-tagged)-Human cystinosis, nephropathic (CTNS), transcript variant 2 | 10 ug |
$457.00
|
|
| RC213151L3 | Lenti ORF clone of Human cystinosis, nephropathic (CTNS), transcript variant 2, Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC213151L4 | Lenti ORF clone of Human cystinosis, nephropathic (CTNS), transcript variant 2, mGFP tagged | 10 ug |
$757.00
|
|
| RG213151 | CTNS (tGFP-tagged) - Human cystinosis, nephropathic (CTNS), transcript variant 2 | 10 ug |
$489.00
$657.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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