ETS2 (NM_005239) Human Untagged Clone
SKU
SC116866
ETS2 (untagged)-Human v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (ETS2)
$457.00
5 Days*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | ETS2 |
| Synonyms | ETS2IT1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_005239 |
| Insert Size | 2560 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_005239.4, NP_005230.1 |
| RefSeq Size | 3672 bp |
| RefSeq ORF | 1410 bp |
| Locus ID | 2114 |
| UniProt ID | P15036 |
| Cytogenetics | 21q22.2 |
| Domains | ETS, SAM_PNT |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Dorso-ventral axis formation |
| Summary | This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2012 Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter protein (isoform 1). |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_005239" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC207377 | ETS2 (Myc-DDK-tagged)-Human v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (ETS2) | 10 ug |
$457.00
|
|
| RC207377L1 | Lenti ORF clone of Human v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (ETS2), Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC207377L2 | Lenti ORF clone of Human v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (ETS2), mGFP tagged | 10 ug |
$757.00
|
|
| RC207377L3 | Lenti ORF clone of Human v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (ETS2), Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC207377L4 | Lenti ORF clone of Human v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (ETS2), mGFP tagged | 10 ug |
$757.00
|
|
| RG207377 | ETS2 (tGFP-tagged) - Human v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (ETS2) | 10 ug |
$489.00
$657.00
|
|
Citations
ETS2 mediated tumor suppressive function and MET oncogene inhibition in human non-small cell lung cancer
Kabbout, Garcia, Fujimoto et al
Clin Cancer Res (2013) 19 (13), 3383-95 DOI: 10.1158/1078-0432.CCR-13-0341
Kabbout, Garcia, Fujimoto et al
Clin Cancer Res (2013) 19 (13), 3383-95 DOI: 10.1158/1078-0432.CCR-13-0341
AI Summary: OriGene products, specifically the ETS2 shRNA (TG314889) and ETS2 cDNA (RC211368), were used in this study to manipulate ETS2 expression in lung cancer cells, enabling the researchers to investigate the tumor suppressive function of ETS2 and its role in inhibiting the MET oncogene in non-small cell lung cancer.
Involvement of V-Ets erythroblastosis virus E26 oncogene homolog 2 in regulation of transcription activity of MDR1 gene
Wang, Zeng, Luo et al
Acta Biochim. Biophys. Sin. (Shanghai) (2012) 44 (9), 752-8 DOI: 10.1093/abbs/gms058
Wang, Zeng, Luo et al
Acta Biochim. Biophys. Sin. (Shanghai) (2012) 44 (9), 752-8 DOI: 10.1093/abbs/gms058
Cited by 4
AI Summary: OriGene's ETS2 expression vector was used in this study to investigate the role of ETS2 in regulating MDR1 gene transcription and P-glycoprotein expression in cancer cells.
Snippet: Brunswick, USA). ETS2 expression vector was purchased from Origene Company (Rockville, USA). Reverse transcription-polymerase chain reaction. Total RNA was extracted from cells or tissue with TRIzol reagent (Invitrogen). The
Up-regulation of Bcl-xl by hepatocyte growth factor in human mesothelioma cells involves ETS transcription factors
Cao, Littlejohn, Rodarte et al
Am J Pathol (2009) 175 (5), 2207-16 DOI: 10.2353/ajpath.2009.090070
Cao, Littlejohn, Rodarte et al
Am J Pathol (2009) 175 (5), 2207-16 DOI: 10.2353/ajpath.2009.090070
Cited by 21
AI Summary: In this study, OriGene products ETS-2 cDNA (RC207825) and PU.1 cDNA (RC201054) were used for transient expression in mesothelioma cell lines to investigate their roles in regulating Bcl-xl promoter activity and expression.
Showing 1-3 of 3 papers.
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