PLK2 (NM_006622) Human Untagged Clone
$691.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | PLK2 |
| Synonyms | hPlk2; hSNK; SNK |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_006622 |
| Insert Size | 2058 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_006622.1, NP_006613.1 |
| RefSeq Size | 2972 bp |
| RefSeq ORF | 2058 bp |
| Locus ID | 10769 |
| UniProt ID | Q9NYY3 |
| Cytogenetics | 5q11.2 |
| Domains | pkinase, POLO_box, S_TKc, TyrKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Summary | The protein encoded by this gene is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen and fetal tissues, and its expression is inducible by serum, suggesting that it may also play an important role in cells undergoing rapid cell division. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2011 Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longer isoform (1). |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
"NM_006622" in other vectors (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC202499 | PLK2 (Myc-DDK-tagged)-Human polo-like kinase 2 (PLK2) | 10 ug |
$941.00
|
|
| RC202499L1 | Lenti ORF clone of Human polo-like kinase 2 (PLK2), Myc-DDK-tagged | 10 ug |
$1,241.00
|
|
| RC202499L2 | Lenti ORF clone of Human polo-like kinase 2 (PLK2), mGFP tagged | 10 ug |
$1,241.00
|
|
| RC202499L3 | Lenti ORF clone of Human polo-like kinase 2 (PLK2), Myc-DDK-tagged | 10 ug |
$1,241.00
|
|
| RC202499L4 | Lenti ORF clone of Human polo-like kinase 2 (PLK2), mGFP tagged | 10 ug |
$1,241.00
|
|
| RG202499 | PLK2 (tGFP-tagged) - Human polo-like kinase 2 (PLK2) | 10 ug |
$1,141.00
|
|
| SC323362 | PLK2 (untagged)-Kinase deficient mutant (K111M) of Human polo-like kinase 2 (Drosophila) (PLK2) | 10 ug |
$942.00
|
|
Citations
Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system
Inglis, Chereau, Brigham et al
J Biol Chem (2009) 284 (5), 2598-2602 DOI: 10.1074/jbc.C800206200
Inglis, Chereau, Brigham et al
J Biol Chem (2009) 284 (5), 2598-2602 DOI: 10.1074/jbc.C800206200
AI Summary: OriGene products contributed to this study by providing PLK2 shRNA constructs used for specific knockdown of PLK2 expression, enabling the authors to demonstrate the role of PLK2 in alpha-synuclein phosphorylation at Ser-129.
Showing 1-1 of 1 papers.
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