SDS (NM_006843) Human Untagged Clone

SKU SC115837

SDS (untagged)-Human serine dehydratase (SDS)

Product Data

• Type: Human Untagged Clone
• Target Symbol: SDS
• Synonyms: SDH
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115837 sequence for NM_006843 edited (data generated by NextGen Sequencing); ATGATGTCTGGAGAACCCCTGCACGTGAAGACCCCCATCCGTGACAGCATGGCCCTGTCC; AAAATGGCCGGCACCAGCGTCTACCTCAAGATGGACAGTGCCCAGCCCTCCGGCTCCTTC; AAGATCCGGGGCATTGGGCACTTCTGCAAGAGGTGGGCCAAGCAAGGCTGTGCACATTTT; GTCTGCTCCTCGGCGGGCAACGCAGGCATGGCGGCTGCATATGCGGCCAGGCAACTCGGC; GTCCCCGCCACCATCGTGGTGCCCAGCACCACACCTGCTCTCACCATTGAGCGCCTCAAG; AATGAAGGTGCCACAGTCAAGGTGGTGGGTGAGTTATTGGATGAAGCCTTCGAGCTGGCC; AAGGCCCTAGCGAAGAACAACCCGGGTTGGGTCTACATTCCCCCCTTTGATGACCCCCTC; ATCTGGGAAGGCCACGCTTCCATCGTGAAAGAGCTGAAGGAGACACTGTGGGAAAAGCCG; GGGGCCATCGCGCTGTCAGTGGGCGGCGGGGGCCTGCTGTGTGGAGTGGTCCAGGGGCTG; CAGGAGGTGGGCTGGGGGGACGTGCCTGTCATCGCCATGGAGACTTTTGGTGCCCACAGC; TTCCACGCTGCCACCACCGCAGGCAAACTTGTCTCCCTGCCCAAGATCACCAGTGTTGCC; AAGGCCCTGGGCGTGAAGACTGTGGGGGCTCAGGCCCTGAAGCTGTTTCAGGAACACCCC; ATTTTCTCTGAAGTTATCTCGGACCAGGAGGCTGTGGCCGCCATTGAGAAGTTCGTGGAT; GATGAGAAGATCCTGGTGGAGCCCGCCTGCGGGGCAGCCCTGGCCGCTGTCTATAGCCAC; GTGATCCAGAAGCTCCAACTGGAGGGGAATCTCCGAACCCCGCTGCCATCCCTCGTGGTC; ATCGTCTGCGGGGGCAGCAACATCAGCCTGGCCCAGCTGCGGGCGCTCAAGGAACAGCTG; GGCATGACAAATAGGTTGCCCAAGTGA; ; Clone variation with respect to NM_006843.2;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006843 unedited; ATTTTGTAATACGACTTACTATAGGGCGGCCGCGAATTCGGCACGAGCCGTCCTCAGCCC; CCTCTCTTCGTGGGCTATCTACTCAGTTGATCCCTCCCTCGCTGGCTTGGCTCTGACTCC; TGCTCAGACCCATCACCTTTGCCGGGAATGATGTCTGGAGAACCCCTGCACGTGAAGACC; CCCATCCGTGACAGCATGGCCCTGTCCAAAATGGCCGGCACCAGCGTCTACCTCAAGATG; GACAGTGCCCAGCCCTCCGGCTCCTTCAAGATCCGGGGCATTGGGCACTTCTGCAAGAGG; TGGGCCAAGCAAGGCTGTGCACATTTTGTCTGCTCCTCGGCGGGCAACGCAGGCATGGCG; GCTGCATATGCGGCCAGGCAACTCGGCGTCCCCGCCACCATCGTGGTGCCCAGCACCACA; CCTGCTCTCACCATTGAGCGCCTCAAGAATGAAGGTGCCACAGTCAAGGTGGTGGGTGAG; TTATTGGATGAAGCCTTCGAGCTGGCCAAGGCCCTAGCGAAGAACAACCCGGGTTGGGTC; TACATTCCCCCCTTTGATGACCCCCTCATCTGGGAAGGCCACGCTTCCATCGTGAAAGAG; CTGAAGGAGACACTGTGGGAAAAGCCGGGGGCCATCGCGCTGTCAGTGGGCGGCGGNGGC; CTGCTGTGTGGAGTGGTCCAGGGGCTGCAGGAGGTGGGCTGNGGGGACGTGCCTGTCATC; GCCATGGAGACTTTTGGTGCCCACAGCTTCCACGCTGCCACCACCGCAGGCAAACTTGTC; TCCCTGCCCCAGATCACCAGTGTTGCCAAGGCCCTGGGCGTGAAGACTGTGGGGGCTCAN; GCCCTGAAGCTGNTTCANGAACACCCCCATTTCTCTGAAGNTATCTCGNACAGNAGGGCT; GTGCCGNCATTGAGAAGTTCGTGGATGATGAGAAGATCCTGNTGGAGCCCGNNCTGCGGG; CAGCCCTGGCCGCTGNCTTAGCCCACGTGAAC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006843 unedited; NNNNTTTTGACTTGNACCCGCGGCCGCATNCTAGNGATCGGTTTTTTTTTTTTTTTTTTT; TTTGGTTCATAAATATATTTTATTTTTCAATGAAAAATTTGCACATTAGAAAAATAGTAA; GGGTCAGGGGTGGGCTTCCTGGGAGGATGGCTGAGATAGTTCCTCAACCCTGGTTGGTGG; CCCTGTTGACCTTCACTGGGAACAAGTTCAGGGGCGAGGTCACAGCTTTGAGGAATTCCT; CACTGCTGTGATTCAGGTCTCTCCTGTCCACCCTGCTCTGGGTACCTGGTGTGTTACTTG; TGGGCACTTGTCACGCCAGCAAGTTGGCTAAGGATGGGCACAGAGCAGTCACACAGATAC; CAAAAAGGTCCAATTCATAGCCTCGCTGGCTGCCGACCTTTGGCCTCTGCATAGTGGGCT; CCTGATAACAAGAAGTTAACCTGCACCCAGGCCACAGGTGCTCAGCCAAACATACGACGA; GGCGCTGGATAAAACTCCAGCCCCTCCAGGGGTCTCTTGGGCTAGGAGAGCACAGATCGG; TAAGGGGTCCGTCCTCACTTGGGCAACCTATTTGTCATGCCCAGCTGTTCCTTGAGCGCC; CGCAGCTGGGCCAGGCTGATGTTGCTGCCCCCGCAGACGATGACCCACGAGGATGGCAGC; GGGGTTCGGAGATTCCCCTCCAGTTGGAGCTTCTGGATCACGTGGCTATAGACAGCGGCC; AGGGCTGCCCCGCNAGCGGGCTCCACCAGGATCTTCTCATCATCCACGAACTTCTCATGG; CGGCCACAGCCTCCTGGTCCGAGATAACTCAGAGAAATGGGGTGTTCCTGAAACAGCTTC; AGGGCCTGAGCCCCCCAGTCTTCACGCCCNAGGCCTTGGCACACTGGTGATCTTGGNCAG; GNNAGACAGTTGC;
• Restriction Sites: NotI-NotI
• ACCN: NM_006843
• Insert Size: 1630 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_006843.2, NP_006834.2
• RefSeq Size: 1620 bp
• RefSeq ORF: 987 bp
• Locus ID: 10993
• UniProt ID: P20132
• Cytogenetics: 12q24.13
• Domains: PALP
• Protein Pathways: Cysteine and methionine metabolism, Glycine, Metabolic pathways, serine and threonine metabolism
• Summary: This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008]