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KAT7 (NM_007067) Human Untagged Clone

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SKU
SC115703
KAT7 (untagged)-Human MYST histone acetyltransferase 2 (MYST2), transcript variant 1
  $570.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol KAT7
Synonyms HBO1; HBOA; MYST2; ZC2HC7
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC115703 sequence for NM_007067 edited (data generated by NextGen Sequencing)
ATGCCGCGAAGGAAGAGGAATGCAGGCAGTAGTTCAGATGGAACCGAAGATTCCGATTTT
TCTACAGATCTCGAGCACACAGACAGTTCAGAAAGTGATGGCACATCCCGACGATCTGCT
CGAGTCACCCGCTCCTCAGCCAGGCTAAGCCAGAGTTCTCAAGATTCCAGTCCTGTTCGA
AATCTGCAGTCTTTTGGCACTGAGGAGCCTGCTTACTCTACCAGAAGAGTGACCCGTAGT
CAGCAGCAGCCTACCCCAGTGACACCGAAAAAATACCCTCTTCGGCAGACTCGTTCATCT
GGTTCAGAAACTGAGCAAGTGGTTGATTTTTCAGATAGAGAAACTAAAAATACAGCTGAT
CATGATGAGTCACCGCCTCGAACTCCAACTGGAAATGCGCCTTCTTCTGAGTCTGACATA
GACATCTCCAGCCCCAATGTATCTCACGATGAGAGCATTGCCAAGGACATGTCCCTGAAG
GACTCAGGCAGTGATCTCTCTCATCGCCCCAAGCGCCGTCGCTTCCATGAAAGCTACAAC
TTCAATATGAAGTGTCCTACACCAGGCTGTAACTCTCTAGGACACCTTACAGGAAAACAT
GAGAGACATTTCTCCATCTCAGGATGCCCACTGTATCATAACCTCTCAGCTGACGAATGC
AAGGTGAGAGCACAGAGCCGGGATAAGCAGATAGAAGAAAGGATGCTGTCTCACAGGCAA
GATGACAACAACAGGCATGCAACCAGGCACCAGGCACCAACGGAGAGGCAGCTTCGATAT
AAGGAAAAAGTGGCTGAACTCAGGAAGAAAAGAAATTCTGGACTGAGCAAAGAACAGAAA
GAGAAATATATGGAACACAGACAGACCTATGGGAACACACGGGAACCTCTTTTAGAAAAC
CTGACAAGCGAGTATGACTTGGATCTTTTCCGAAGAGCACAAGCCCGGGCTTCAGAGGAT
TTGGAGAAGTTAAGGCTGCAAGGCCAAATCACAGAGGGAAGCAACATGATTAAAACAATT
GCTTTTGGCCGCTATGAGCTTGATACCTGGTATCATTCTCCATATCCTGAAGAATATGCA
CGGCTGGGACGTCTCTATATGTGTGAATTCTGTTTAAAATATATGAAGAGCCAAACGATA
CTCCGCCGGCACATGGCCAAATGTGTGTGGAAACACCCACCTGGTGATGAGATATATCGC
AAAGGTTCAATCTCTGTGTTTGAAGTGGATGGCAAGAAAAACAAGATCTACTGCCAAAAC
CTGTGCCTGTTGGCCAAACTTTTTCTGGACCACAAGACATTATATTATGATGTGGAGCCC
TTCCTGTTCTATGTTATGACAGAGGCGGACAACACTGGCTGTCACCTGATTGGATATTTT
TCTAAGGAAAAGAATTCATTCCTCAACTACAACGTCTCCTGTATCCTTACTATGCCTCAG
TACATGAGACAGGGCTATGGCAAGATGCTTATTGATTTCAGTTATTTGCTTTCCAAAGTC
GAAGAAAAAGTTGGCTCCCCAGAACGTCCACTCTCAGATCTGGGGCTTATAAGCTATCGC
AGTTACTGGAAAGAAGTACTTCTCCGCTACCTGCATAATTTTCAAGGCAAAGAGATTTCT
ATCAAAGAAATCAGTCAGGAGACGGCTGTGAATCCTGTGGACATTGTCAGCACTCTGCAA
GCCCTTCAGATGCTCAAATACTGGAAGGGAAAACACCTAGTTTTAAAGAGACAGGACCTG
ATTGATGAGTGGATAGCCAAAGAGGCCAAAAGGTCCAACTCCAATAAAACCATGGATCCC
AGCTGCTTAAAATGGACCCCTCCCAAGGGCACTTAA

Clone variation with respect to NM_007067.4
5' Read Nucleotide Sequence
>OriGene 5' read for NM_007067 unedited
TTTGTATACGACTCATATAGGCGGCNCGCGATTCGGCACGAGGGTTCCTGCTGCTGCCGC
CGCTGCCCGAATCGGAACCGTCGGGCCGCAGCCGCCGGCAATGCCGCGAAGGAAGAGGAA
TGCAGGCAGTAGTTCAGATGGAACCGAAGATTCCGATTTTTCTACAGATCTCGAGCACAC
AGACAGTTCAGAAAGTGATGGCACATCCCGACGATCTGCTCGAGTCACCCGCTCCTCAGC
CAGGCTAAGCCAGAGTTCTCAAGATTCCAGTCCTGTTCGAAATCTGCAGTCTTTTGGCAC
TGAGGAGCCTGCTTACTCTACCAGAAGAGTGACCCGTAGTCAGCAGCAGCCTACCCCAGT
GACACCGAAAAAATACCCTCTTCGGCAGACTCGTTCATCTGGTTCAGAAACTGAGCAAGT
GGTTGATTTTTCAGATAGAGAAACTAAAAATACAGCTGATCATGATGAGTCACCGCCTCG
AACTCCAACTGGAAATGCGCCTTCTTCTGAGTCTGACATAGACATCTCCAGCCCCAATGT
ATCTCACGATGAGAGCATTGCCAAGGACATGTCCCTGAAGGACTCAGGCAGTGATCTCTC
TCATCGCCCCAAGCGCCGTCGCTTCCATGAAAGCTACAACTTCAATATGAAGTGTCCTAC
ACCAGGCTGTAACTCTCTAGGACACCTTACAGGAAAACATGAGAGACATTTCTCCATCTC
AGGATGCCCACTGTATCATAACCTCTCAGCTGACGAATGGCANGGTGAGAGCACAGAGCC
GGGATAAGCAGATAGAAGAAAGGATGCTGTCTCACAGGCAGAATGACAACACAGGCATGG
CACNNCAGCACCAGCACCACGGNAGAGGCAGCTTCGTATAGGGAAAAAGTGGNCTGACTC
AGAGAAAAGAATTCTGGACTGAGCAAGACAGAAGAGATATATGAAA
3' Read Nucleotide Sequence
>OriGene 3' read for NM_007067 unedited
GAGTCGAGTTTTTTTTTTTTTTTTTTGAGCAGAGACATGCTTTATTGAGGAGTAGATATA
GAAGAGCACATTCTACCACATGTGGGGAAGGGTTTAGCTTCTGTAAAAGGCCTTTATCCC
TTAAGAAAACCCCTAGTGAAGTTGCTTTTTGATAAATTTTAACAGTGACACTGAAACTGG
AGGGGAGCTGCCACTGAACATGCTTAAAATTAGCTCCCCCAACCCACAGTGAATATAAGT
AGTGTACAGAGATGACAAGAGAAAGGCACAAATGACCGGAGTCAGGGATTGTGGTGAGGG
CTCCACATGAAGACAGCATGTTGGAGGAGACCAAGTTGGGAAGGGTGACATGTCATACAT
CAAAAGTTGCCCCAAGATAGCAGGTTATAATGGGCTAGAGAGAAATTAGAGGGAACATCT
CTTCCTTCACTTGAACAACACCAAAAATAGAAGACCAGAGAATAGAAGGATGGTGACAAA
TCCCAAAAAGGAAATGGAGGAGGAGTTCGTGGAAGGGCAGAAGCACTTTAATCCTANAGG
GANGGTGAGGCACTGTTGAAAAGAAGAGCANACTTTGGCAGGNGTGGCCATTCTGCCTTG
CTGAGTCATGGGCTGAGATCGGAAGTCACTTTCATCATTTTCTACTTCTCCAGGGCACTC
AGACAAATCAGTGATGGTATATGGAAGTACAGATGTACTGTATCAGACTAGTGGNAGTGA
AAAGGTTNCTGCAGTATATTAACCAGTTATATGCAGCATGAAAGGGAAAGTGGACATTAC
TTTTGCACCTGCAACGTAAAAAGTGGGATAANGAGAGAAGGAATATTACTAGTGAGTCTT
TACNGTGAGCAAAAAGTGTATTCGTTCCTTTCACNAAACACTGCCCTGNCACTGNCACAA
GTGACTCAATAAACCAGAACCACACCCTTCATCTTTCTNCATTCATCAGACAATATTGCT
ATACATGACAGCCCTGGGACTCTTCAAGATTNGCCTTGTTAGCCAACGATCAAAAAGTCT
CTATCAATGAAAATAAGCAA
Restriction Sites NotI-NotI |
ACCN NM_007067
Insert Size 3600 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_007067.3, NP_008998.1
RefSeq Size 3600 bp
RefSeq ORF 1836 bp
Locus ID 11143
UniProt ID O95251
Cytogenetics 17q21.33
Domains MOZ_SAS, zf-C2H2, zf-C2HC
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Summary The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed. provided by RefSeq, Oct 2016
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
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Documents
Resources
"NM_007067" in other vectors (6)
SKU Description Size Price
RC207554 KAT7 (Myc-DDK-tagged)-Human MYST histone acetyltransferase 2 (MYST2), transcript variant 1 10 ug
$569.00
RC207554L1 Lenti ORF clone of Human MYST histone acetyltransferase 2 (MYST2), transcript variant 1, Myc-DDK-tagged 10 ug
$869.00
RC207554L2 Lenti ORF clone of Human MYST histone acetyltransferase 2 (MYST2), transcript variant 1, mGFP tagged 10 ug
$869.00
RC207554L3 Lenti ORF clone of Human MYST histone acetyltransferase 2 (MYST2), transcript variant 1, Myc-DDK-tagged 10 ug
$869.00
RC207554L4 Lenti ORF clone of Human MYST histone acetyltransferase 2 (MYST2), transcript variant 1, mGFP tagged 10 ug
$869.00
RG207554 KAT7 (tGFP-tagged) - Human MYST histone acetyltransferase 2 (MYST2), transcript variant 1 10 ug
$489.00 $769.00

file-alt Citations

LPS promotes HBO1 stability via USP25 to modulate inflammatory gene transcription in THP-1 cells
Long, Lai, Li et al
Biochim Biophys Acta Gene Regul Mech (2018) 1861 (9), 773-782 DOI: 10.1016/j.bbagrm.2018.08.001
Cited by 25
AI Summary: OriGene products, specifically the anti-HBO1 antibody (TA324435) and USP25 cDNA clone (RC208636), were used in this study to detect HBO1 protein levels and to overexpress USP25, respectively, enabling the investigation of their roles in LPS-induced inflammatory gene transcription in THP-1 cells.
FigureFigure
Genetic alterations and oncogenic pathways associated with breast cancer subtypes
Hu, Stern, Ge et al
Mol Cancer Res (2009) 7 (4), 511-22 DOI: 10.1158/1541-7786.MCR-08-0107
AI Summary: OriGene products, specifically the MYST2 cDNA clone, were used in this study to experimentally test and validate the oncogenic potential of MYST2 in breast cancer cell growth assays.
Showing 1-2 of 2 papers.
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