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FBXL7 (NM_012304) Human Untagged Clone

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SKU
SC115444
FBXL7 (untagged)-Human F-box and leucine-rich repeat protein 7 (FBXL7)
  $457.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol FBXL7
Synonyms FBL6; FBL7
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC115444 sequence for NM_012304 edited (data generated by NextGen Sequencing)
ATGGGCGCGAACAATGGCAAACAGTACGGCAGTGAGGGCAAAGGCAGCTCGAGCATCTCA
TCTGACGTGAGTTCAAGTACAGATCACACGCCCACTAAAGCCCAGAAGAATGTGGCTACC
AGCGAAGACTCCGACCTGAGCATGCGCACACTGAGCACGCCCAGCCCAGCCCTGATATGT
CCACCGAATCTCCCAGGATTTCAGAATGGAAGGGGCTCGTCCACCTCCTCGTCCTCCATC
ACCGGGGAGACGGTGGCCATGGTGCACTCCCCGCCCCCGACCCGCCTCACACACCCGCTC
ATCCGGCTCGCCTCCAGACCCCAGAAGGAGCAGGCCAGCATAGACCGGCTCCCGGACCAC
TCCATGGTGCAGATCTTCTCCTTCCTGCCCACCAACCAGCTGTGCCGCTGCGCGCGAGTG
TGCCGCCGCTGGTACAACCTGGCCTGGGACCCGCGGCTCTGGAGGACTATCCGCCTGACG
GGCGAGACCATCAACGTGGACCGCGCCCTCAAGGTGCTGACCCGCAGACTCTGCCAGGAC
ACCCCCAACGTGTGTCTCATGCTGGAAACCGTAACTGTCAGTGGCTGCAGGCGGCTCACA
GACCGAGGGCTGTACACCATCGCCCAGTGCTGCCCCGAACTGAGGCGACTGGAAGTCTCA
GGCTGTTACAATATCTCCAACGAGGCCGTCTTTGATGTGGTGTCCCTCTGCCCTAATCTG
GAGCACCTGGATGTGTCAGGATGCTCCAAAGTGACCTGCATCAGCTTGACCCGGGAGGCC
TCCATTAAACTGTCACCCTTGCATGGCAAACAGATTTCCATCCGCTACCTGGACATGACG
GACTGCTTCGTGCTGGAGGACGAAGGCCTGCACACCATCGCGGCGCACTGCACGCAGCTC
ACCCACCTCTACCTGCGCCGCTGCGTCCGCCTGACCGACGAAGGCCTGCGCTACCTGGTG
ATCTACTGCGCCTCCATCAAGGAGCTGAGCGTCAGCGACTGCCGCTTCGTCAGCGACTTC
GGCCTGCGGGAGATCGCCAAGCTGGAGTCCCGCCTGCGGTACCTGAGCATCGCGCACTGC
GGCCGGGTCACCGACGTGGGCATCCGCTACGTGGCCAAGTACTGCAGCAAGCTGCGCTAC
CTCAACGCGAGGGGCTGCGAGGGCATCACGGACCACGGTGTGGAGTACCTCGCCAAGAAC
TGCACCAAACTCAAATCCCTGGATATCGGCAAATGCCCTTTGGTATCCGACACGGGCCTG
GAGTGCCTGGCCCTGAACTGCTTCAACCTCAAGCGGCTCAGCCTCAAGTCCTGCGAGAGC
ATCACCGGCCAGGGCTTGCAGATCGTGGCCGCCAACTGCTTTGACCTCCAGACGCTGAAT
GTCCAGGACTGCGAGGTCTCCGTGGAGGCCCTGCGCTTTGTCAAACGCCACTGCAAGCGC
TGCGTCATCGAGCACACCAACCCGGCTTTCTTCTGA

Clone variation with respect to NM_012304.3
5' Read Nucleotide Sequence
>OriGene 5' read for NM_012304 unedited
AAAATTTTGTAATACGACTCACTATAGGGCGGCCCGCGATTCGGCACGAGGGTCGGGCGG
GCTTTCCTCGGGCCGAGCGCGCAGGACGTGCGCCGCAGCTATGGAGTGTCCCGGGAGACG
GCGGGCATGACGGCTACAGGATGGGCGCGAACAATGGCAAACAGTACGGCAGTGAGGGCA
AAGGCAGCTCGAGCATCTCATCTGACGTGAGTTCAAGTACAGATCACACGCCCACTAAAG
CCCAGAAGAATGTGGCTACCAGCGAAGACTCCGACCTGAGCATGCGCACACTGAGCACGC
CCAGCCCAGCCCTGATATGTCCACCGAATCTCCCAGGATTTCAGAATGGAAGGGGCTCGT
CCACCTCCTCGTCCTCCATCACCGGGGAGACGGTGGCCATGGTGCACTCCCCGCCCCCGA
CCCGCCTCACACACCCGCTCATCCGGCTCGCCTCCAGACCCCAGAAGGAGCAGGCCAGCA
TAGACCGGCTCCCGGACCACTCCATGGTGCAGATCTTCTCCTTCCTGCCCACCAACCAGC
TGTGCCGCTGCGCGCGAGTGTGCCGCCGCTGGTACAACCTGGCCTGGGACCCGCGGCTCT
GGAGGACTATCCGCCTGACGGGCGAGACCATCAACGTGGACCGCGCCCTCAAGGTGCTGA
CCCGCAGACTCTGCCAGGACACCCCCAACGTGTGTCTCATGCTGGAAACCGTAACTGTCA
GTGGCTGCAGGCGGCTCACAGACCGAGGGCTGTACACCATCGCCCAGTGCTGCCCCGAAC
TGANGCGACTGGAAGTCTCAGGCTGTTACAATATCTNCCAACGAGCCCGCTTTGATGTTG
TGTCCCTCTGNCCTAATCTGGAGCACCTGGATGTGTTCAGATGCTNCCAAAGTGACCTGC
ATCAGCTTGACCCCGGGAGCCTNCATNAAACTGTCACCCTTGCATGGCAAACAGATTCCA
TN
3' Read Nucleotide Sequence
>OriGene 3' read for NM_012304 unedited
TATAGCTATGCNACCGCGGCCGCAATCTAGNGATCGGGTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTACGAACATATTGCTTTATTTCTTGGTAGAAAATTAAGGCTTTCTAAAT
TCATACAGCACGCAGGGATTTGAACATTAGAATTAAAAAACAACAACAACAAACAATGAG
CATTCAATTTAGCAGAGCCAGGAAGGAAGCAATGTTTTAAAACAGATAAATTTCCTAGGG
AGACCTTTGGTTTGGTCTCCAAAAATCTGCTGAGCTGTTTCCCCAGTAACCTCCATCATA
GATTCCCACCCCAAGGGAGAACAGAATGGATGAACAGGAGACTGGGAGAAAAGAAAAAAC
TGGCAAGACGGTATGTGCTGGGCAATCAGTGGGAACAGTCAGCTTTGTCTCATGTTTGGA
AAACAGTTTAGGGGATGCGGCCAGGGATTCATTCTCTGGATCTCCCTGCTCATTCTCAGA
GTATTAAACCAGCTCACTCGGAAGACCCCAGGGCCAAGGATTAGGGACAATCCTTTGTGA
CACCCAAATCCTGAAACTTCAAATAGGGTCACAAGTCACAGAGCTGAGGAATGCTGCCTT
CAACTTCTTTCATGGTTTTAAACTCTGTGGCTTTCACTAGATCCTGGCCTAGCTAAATGA
TTCATTTCCCCCATGGCACAGGAGCCTTGATTACACATGTAAATTTGATGATTGTTGATT
GGGACGGCACGCCATGATGTTTCGAAAGAAAACCTTCTGGGGCAGAAACCAACTTNATAA
CACTTAACCTTTTCNATCCCCCACAAAAAAACAACAGTTTGCCCACGCACCCTTACAGNA
GGAGTGGATGTGCGCAAGGGTGGTCTAACNTTGACAAATTCACCATAACTGGCTTGGAGA
TCGCAAAGGTTTCGGATTGGGAAAATGGGCATTCTGGAGAAAAAATAAAGTGAGTGATTC
CACCGCACAAAAGGTGGGG
Restriction Sites NotI-NotI |
ACCN NM_012304
Insert Size 4420 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_012304.3, NP_036436.1
RefSeq Size 4562 bp
RefSeq ORF 1476 bp
Locus ID 23194
UniProt ID Q9UJT9
Cytogenetics 5p15.1
Domains F-box, LRR, LRR_CC
Protein Families Druggable Genome
Summary This gene encodes a member of the F-box protein family which is characterized by a 42-48 amino acid motif, the F-box, which binds to the S-phase kinase-associated protein 1 (Skp1) protein. The F-box proteins constitute one of the four subunits of E3 ubiquitin protein ligases called SCFs (SKP1-Cul1-F-box), which play a role in phosphorylation-dependent ubiquitination of proteins. The F-box proteins are divided into 3 subfamilies based on the other domain in the protein: F-box proteins that also have a WD-40 domain (Fbws subfamily), F-box proteins that also have leucine-rich repeats (Fbls subfamily) and F-box proteins that contain other motifs or lack known protein-interaction domains (Fbxs subfamily). The protein encoded by this gene belongs to the Fbls subfamily. Alternative splicing results in multiple transcript variants of this gene. provided by RefSeq, May 2013
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
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Documents
Resources
"NM_012304" in other vectors (6)
SKU Description Size Price
RC210441 FBXL7 (Myc-DDK-tagged)-Human F-box and leucine-rich repeat protein 7 (FBXL7) 10 ug
$457.00
RC210441L1 Lenti ORF clone of Human F-box and leucine-rich repeat protein 7 (FBXL7), Myc-DDK-tagged 10 ug
$757.00
RC210441L2 Lenti ORF clone of Human F-box and leucine-rich repeat protein 7 (FBXL7), mGFP tagged 10 ug
$757.00
RC210441L3 Lenti ORF clone of Human F-box and leucine-rich repeat protein 7 (FBXL7), Myc-DDK-tagged 10 ug
$757.00
RC210441L4 Lenti ORF clone of Human F-box and leucine-rich repeat protein 7 (FBXL7), mGFP tagged 10 ug
$757.00
RG210441 FBXL7 (tGFP-tagged) - Human F-box and leucine-rich repeat protein 7 (FBXL7) 10 ug
$489.00 $657.00

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