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CD299 (CLEC4M) (NM_014257) Human Untagged Clone

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SKU
SC115079
CLEC4M (untagged)-Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1
  $457.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol CD299
Synonyms CD209L; CD299; DC-SIGN2; DC-SIGNR; DCSIGNR; HP10347; L-SIGN; LSIGN
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_014257 edited
TGAGGATCAGAGGGTGGAAAATAAAAGCTGTGGTCCCCAGGAGTCCTGAACATCTGGGGA
CAGCGGGAAAACATGAGTGACTCCAAGGAACCAAGGGTGCAGCAGCTGGGCCTCCTGGAA
GAAGATCCAACAACCAGTGGCATCAGACTTTTTCCAAGAGACTTTCAATTCCAGCAGATA
CATGGCCACAAGAGCTCTACAGGGTGTCTTGGCCATGGCGCCCTGGTGCTGCAACTCCTC
TCCTTCATGCTCTTGGCTGGGGTCCTGGTGGCCATCCTTGTCCAAGTGTCCAAGGTCCCC
AGCTCCCTAAGTCAGGAACAATCCGAGCAAGACGCAATCTACCAGAACCTGACCCAGCTT
AAAGCTGCAGTGGGTGAGCTCTCAGAGAAATCCAAGCTGCAGGAGATCTACCAGGAGCTG
ACCCAGCTGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAATCCAAGCTGCAGGAGATCTAC
CAGGAGCTGACCCGGCTGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAATCCAAGCTGCAG
GAGATCTACCAGGAGCTGACCCGGCTGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAATCC
AAGCTGCAGGAGATCTACCAGGAGCTGACCCGGCTGAAGGCTGCAGTGGGTGAGTTGCCA
GAGAAATCCAAGCTGCAGGAGATCTACCAGGAGCTGACGGAGCTGAAGGCTGCAGTGGGT
GAGTTGCCAGAGAAATCCAAGCTGCAGGAGATCTACCAGGAGCTGACCCAGCTGAAGGCT
GCAGTGGGTGAGTTGCCAGACCAGTCCAAGCAGCAGCAAATCTATCAAGAACTGACCGAT
TTGAAGACTGCATTTGAACGCCTGTGCCGCCACTGTCCCAAGGACTGGACATTCTTCCAA
GGAAACTGTTACTTCATGTCTAACTCCCAGCGGAACTGGCACGACTCCGTCACCGCCTGC
CAGGAAGTGAGGGCCCAGCTCGTCGTAATCAAAACTGCTGAGGAGCAGAACTTCCTACAG
CTGCAGACTTCCAGGAGTAACCGCTTCTCCTGGATGGGACTTTCAGACCTAAATCAGGAA
GGCACGTGGCAATGGGTGGACGGCTCACCTCTGTCACCCAGCTTCCAGCGGTACTGGAAC
AGTGGAGAACCCAACAATAGCGGGAATGAAGACTGTGCGGAATTTAGTGGCAGTGGCTGG
AACGACAATCGATGTGACGTTGACAATTACTGGATCTGCAAAAAGCCCGCAGCCTGCTTC
AGAGACGAATAGTTGTTTCCCTGCTAGCCTCAGCCTCCATTGTGGTATAGCAGAACTTCA
CCCACTTGTAAGCCAGCGCTTCTTCTCTCCATCCTTGGACCTTCACAAATGCCCTGAGAC
GGTTCTCTGTTCGATTTTTCATCCCCTATGAACCTGGGTCTTATTCTGTCCTTCTGATGC
CTCCAAGTTTCCCTGGTGTAGAGCTTGTGTTCTTGGCCCATCCTTGGAGCTTTATAAGTG
ACCTGAGTGGGATGCATTTAGGGGGCGGGCTTGGTATGTTGTATGAATCCACTCTCTGTT
CCTTTTGGAGATTAGACTATTTGGATTCATGTGTAGCTGCCCTGTCCCCTGGGGCTTTAT
CTCATCCATGCAAACTACCATCTGCTCAACTTCCAGCTACACCCCGTGCACCCTTTTGAC
TGGGGACTTGCTGGTTGAAGGAGCTCATCTTGCAGGCTGGAAGCACCAGGGAATTAATTC
CCCCAGTCAACCAATGGCATCCAGAGAGGGCATGGAGGCTCCATACAACCTCTTCCACCC
CCACATCTTTCTTTGTCCTATACATGTCTTCCATTTGGCTGTTTCTGAGTTGTAGCCTTT
ATAATAAAGTGGTAAATGTTGTAACTGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_014257 unedited
NGGACGTTCACATTTGTAAACGACTCATATAGGGCGGCCGCGATTCCCGGGATTGAGGAT
CAGAGGGTGNGAAAATAAAAGCTGTGGTCCCCAGGAGTCCTGACATCTGGGGACAGCGGG
AAAACATGAGTGACTCCAAGGAACCAAGGGTGCAGCAGCTGGGCCTCCTGGAAGAAGATC
CAACAACCAGTGGCATCAGACTTTTTCCAAGAGACTTTCAATTCCAGCAGATACATGGCC
ACAAGAGCTCTACAGGGTGTCTTGGCCATGGCGCCCTGGTGCTGCAACTCCTCTCCTTCA
TGCTCTTGGCTGGGGTCCTGGTGGCCATCCTTGTCCAAGTGTCCAAGGTCCCCAGCTCCC
TAAGTCAGGAACAATCCGAGCAAGACGCAATCTACCAGAACCTGACCCAGCTTAAAGCTG
CAGTGGGTGAGCTCTCAGAGAAATCCAAGCTGCAGGAGATCTACCAGGAGCTGACCCAGC
TGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAATCCAAGCTGCAGGAGATCTACCAGGAGC
TGACCCGGCTGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAATCCAAGCTGCAGGAGATCT
ACCAGGAGCTGACCCGGCTGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAATCCAAGCTGC
AGGAGATCTACCAGGAGCTGACCCGGCTGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAAT
CCAAGCTGCAGGAGATCTACCAGGAGCTGACGGAGCTGAAGGCTGCAGTGGGTGAGTTGC
CAGAGAAATCCAAGCTGCANGAGATCTACCAGGAGCTGACCCAGCTGAANGCTGCAGTGG
GTGAGTTGCCAGACCAGTCCAAGCAGCAGCAAATCTATCAAGAACTGACCGATTGNGAGA
CTGCA
Restriction Sites Please inquire |
ACCN NM_014257
Insert Size 1930 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_014257.3, NP_055072.3
RefSeq Size 1930 bp
RefSeq ORF 1200 bp
Locus ID 10332
UniProt ID Q9H2X3
Cytogenetics 19p13.2
Protein Families Druggable Genome, Transmembrane
Summary This gene encodes a C-type lectin that functions in cell adhesion and pathogen recognition. This receptor recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including tuberculosis mycobacteria, and viruses including Ebola, hepatitis C, HIV-1, influenza A, West Nile virus and the SARS-CoV acute respiratory syndrome coronavirus. The protein is organized into four distinct domains: a C-terminal carbohydrate recognition domain, a flexible tandem-repeat neck domain of variable length, a transmembrane region and an N-terminal cytoplasmic domain involved in internalization. This gene is closely related in terms of both sequence and function to a neighboring gene, CD209 (Gene ID: 30835), also known as DC-SIGN. The two genes differ in viral recognition and expression patterns, with this gene showing high expression in endothelial cells of the liver, lymph node and placenta. Polymorphisms in the tandem repeat neck domain are associated with resistance to SARS infection. provided by RefSeq, May 2020
Transcript Variant: This variant (1) encodes the longest isoform (1).
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"NM_014257" in other vectors (6)
SKU Description Size Price
RC207947 CLEC4M (Myc-DDK-tagged)-Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1 10 ug
$457.00
RC207947L1 Lenti ORF clone of Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1, Myc-DDK-tagged 10 ug
$757.00
RC207947L2 Lenti ORF clone of Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1, mGFP tagged 10 ug
$757.00
RC207947L3 Lenti ORF clone of Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1, Myc-DDK-tagged 10 ug
$757.00
RC207947L4 Lenti ORF clone of Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1, mGFP tagged 10 ug
$757.00
RG207947 CLEC4M (tGFP-tagged) - Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1 10 ug
$489.00 $657.00

file-alt Citations

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