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S2P (MBTPS2) (NM_015884) Human Untagged Clone

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SKU
SC114571
MBTPS2 (untagged)-Human membrane-bound transcription factor peptidase, site 2 (MBTPS2)
  $726.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol S2P
Synonyms BRESEK; IFAP; KFSD; KFSDX; OI19; OLMSX; S2P
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC114571 sequence for NM_015884 edited (data generated by NextGen Sequencing)
ATGATTCCGGTGTCGCTGGTGGTGGTGGTGGTGGGTGGCTGGACTGTCGTCTACCTGACC
GACTTGGTGCTGAAGTCATCTGTCTATTTTAAACATTCTTATGAAGACTGGCTGGAAAAC
AACGGACTGAGCATCTCCCCTTTCCACATAAGATGGCAAACTGCTGTTTTCAATCGTGCC
TTTTACAGTTGGGGACGGCGGAAAGCAAGGATGCTTTACCAATGGTTCAATTTTGGAATG
GTGTTTGGCGTAATTGCCATGTTTAGCTCATTTTTTCTCCTTGGAAAAACGCTGATGCAG
ACTTTGGCACAAATGATGGCTGACTCTCCCTCTTCTTATTCTTCCTCCTCTTCTTCCTCT
TCCTCCTCTTCTTCCTCTTCCTCTTCTTCATCTTCTTCCTCTTCCTCGCTTCACAATGAA
CAGGTGTTACAAGTTGTGGTTCCTGGTATAAATTTACCCGTCAATCAACTGACCTATTTC
TTCACGGCAGTTCTCATTAGTGGTGTTGTACATGAAATTGGACATGGGATAGCAGCTATT
AGGGAACAAGTTCGATTTAATGGCTTTGGGATTTTTCTCTTCATTATTTATCCTGGAGCA
TTTGTTGATCTGTTCACCACTCATTTGCAACTTATATCGCCAGTCCAGCAGCTAAGGATA
TTTTGTGCAGGTATCTGGCATAATTTTGTCCTTGCACTCTTGGGTATTTTAGCTCTTGTT
CTCCTCCCAGTAATTCTCTTGCCATTTTACTACACTGGAGTTGGGGTGCTCATCACTGAA
GTTGCTGAGGACTCTCCTGCCATTGGACCCAGAGGCCTTTTTGTGGGAGACCTTGTCACC
CATCTACAGGATTGTCCTGTTACTAATGTGCAAGATTGGAATGAATGTTTAGATACCATC
GCCTATGAGCCCCAAATTGGTTACTGTATAAGTGCATCAACTTTACAGCAGTTAAGTTTC
CCAGTTAGAGCATACAAACGACTAGATGGTTCAACTGAATGCTGTAACAATCACAGCCTC
ACAGATGTGTGCTTTTCCTACAGAAATAATTTTAATAAGCGTTTGCATACATGTCTTCCT
GCCCGGAAAGCAGTTGAAGCAACTCAAGTTTGCAGAACCAATAAAGACTGTAAAAAAAGC
TCAAGTTCAAGTTTCTGTATAATACCTTCTTTGGAAACTCACACTCGCTTAATAAAAGTA
AAACACCCACCTCAGATTGATATGTTATACGTAGGACATCCTCTGCATCTTCACTACACA
GTGAGCATCACCAGTTTTATCCCACGTTTTAACTTTCTAAGCATAGATCTGCCAGTGGTT
GTGGAGACATTTGTCAAGTACCTGATTTCCCTCTCAGGAGCTCTGGCTATTGTTAATGCA
GTACCCTGCTTTGCTTTGGATGGACAATGGATTCTAAACTCTTTCTTGGATGCCACCCTT
ACCTCAGTGATTGGAGACAATGATGTCAAAGATCTAATAGGGTTTTTCATCTTGCTGGGT
GGCAGTGTACTTTTGGCTGCCAATGTGACCCTGGGACTCTGGATGGTTACAGCACGGTAA

Clone variation with respect to NM_015884.3
5' Read Nucleotide Sequence
>OriGene 5' read for NM_015884 unedited
TACGACTCCTATAGGCGGCCGCGACTTCGGCACGAGGGCTGGGGCTGTAAGGCGCGCGCG
GTCAGCTGTTGGCGGTGCAGGGAGGAAGACGCCGGGGCTCGCCTTCCCTCCTCTGCCGCC
GCTGCCGCCATGATTCCGGTGTCGCTGGTGGTGGTGGTGGTGGGTGGCTGGACTGTCGTC
TACCTGACCGACTTGGTGCTGAAGTCATCTGTCTATTTTAAACATTCTTATGAAGACTGG
CTGGAAAACAACGGACTGAGCATCTCCCCTTTCCACATAAGATGGCAAACTGCTGTTTTC
AATCGTGCCTTTTACAGTTGGGGACGGCGGAAAGCAAGGATGCTTTACCAATGGTTCAAT
TTTGGAATGGTGTTTGGCGTAATTGCCATGTTTAGCTCATTTTTTCTCCTTGGAAAAACG
CTGATGCAGACTTTGGCACAAATGATGGCTGACTCTCCCTCTTCTTATTCTTCCTCCTCT
TCTTCCTCTTCCTCCTCTTCTTCCTCTTCCTCTTCTTCATCTTCTTCCTCTTCCTCGCTT
CACAATGAACAGGTGTTACAAGNTTGTGGTTCCTGGTATAAATTTACCCGTCAATCAACT
GACCTATTTCTTCACGGCAGTTCTCATTAGTGGGTGTNGTACATGAANATGGACATGGGA
TAGCAGCTATTAGGGAACAAGTTCGATTTAATGGCTTTGGGGATTTTTCTCTTATTATTT
ATCCTGGAGCATTTNGTGGATCTGTTCACCACTCATTTGCACTTATATTCGCAGTCCAGC
ACTAAGATAATTTGTGCAGTATCTGCATAATTTTGTCCTGACTCTGGGGAATTTAGCTTT
GGTCTCTCCAGAATTCTTTGCATTTAAACTGGAGAGGGGGGGCCATACTGAGTGCTGAGG
ACTTCTCCTTGACAAGCCTTTTTGGGAAAACTTACCCTTCAAGATGTCTGTCTATGGGAG
ATGGAAAAGGTTAACCCCA
3' Read Nucleotide Sequence
>OriGene 3' read for NM_015884 unedited
CCAAATTGTGTGTATTGACCCCATATAACGCTTTAATTAAAAACATGCTTAGTTCATGCA
ATCAAATTAATTATATAAGTATTTCATGGCATTCTCCAGCTCTATACTTGAACAGGTCTG
ACTGAGCATTACTATGCTAATGTACTCTGATCCCAAATGATTGTCTACCTAAAAATAGAA
CAAATACTGTATTTTCTGGAATAAACCAATAATTTTTATGGTTTTAGTACTGGTATTAAC
TGATGACCCAAGTCATTAATAAAATGTTAAAATTATATTCAACATCTAATTACTGTTAAG
GCAAATTTGTAATACAATCTAAAAAGTTTCTTAAAAATGATTAAAAAGTTTTAGTGCTTA
CAGAGCAACTCAATAATCTGAAAAAGGTAACCCCATGGAATACATCACTCAGTAAAGAAG
TTGGATAGATGGCTATTAATGAGTTATTGCCCTTAGTCACTTCTGAGTATACAAGAGAAG
CATGTATTTTCCATCAAAGAAACAGCAAGCTCATATACTCCTAGGACCAATAGCTTCACA
CTGGCCTGCTGACTCCCCAAATTTCCCAGGGCTGCATCTCCACTCCAAAAGACCTCAAAG
CAGGCGTGGCTCTTCTGGGCTCAAGAATCAGTTCCCAAGCCCTGGAAAATCCACGTGTGT
ACTCACGTATAGCCATTCTCACTATACTACCAAGTCTTCTGTGGACCCAGAGAGGTAGCT
TAGGAGAGAGACAGAANAACAGGACTAGGTACTTAATAACCTGACACAGGAAAACATGGG
AGCCGCTGGTGAGGACAGAGTATGGCTCAGAGTTTAAGGTCATTGCTTCTTGGAGACAGA
AACCCAGNAGCTAGGCCCCAGATGTCCTGAGCAGCACAGGAAAGATGTTTACCCTGGAAG
GTTTCCN
Restriction Sites NotI-NotI |
ACCN NM_015884
Insert Size 3000 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_015884.1, NP_056968.1
RefSeq Size 1759 bp
RefSeq ORF 1560 bp
Locus ID 51360
UniProt ID O43462
Cytogenetics Xp22.12
Domains Peptidase_M50
Protein Families Druggable Genome, Protease, Transmembrane
Summary This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.provided by RefSeq, Aug 2009
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Documents
Resources
"NM_015884" in other vectors (6)
SKU Description Size Price
RC218791 MBTPS2 (Myc-DDK-tagged)-Human membrane-bound transcription factor peptidase, site 2 (MBTPS2) 10 ug
$725.00
RC218791L1 Lenti ORF clone of Human membrane-bound transcription factor peptidase, site 2 (MBTPS2), Myc-DDK-tagged 10 ug
$1,025.00
RC218791L2 Lenti ORF clone of Human membrane-bound transcription factor peptidase, site 2 (MBTPS2), mGFP tagged 10 ug
$1,025.00
RC218791L3 Lenti ORF clone of Human membrane-bound transcription factor peptidase, site 2 (MBTPS2), Myc-DDK-tagged 10 ug
$1,025.00
RC218791L4 Lenti ORF clone of Human membrane-bound transcription factor peptidase, site 2 (MBTPS2), mGFP tagged 10 ug
$1,025.00
RG218791 MBTPS2 (tGFP-tagged) - Human membrane-bound transcription factor peptidase, site 2 (MBTPS2) 10 ug
$925.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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